Prevalência de fluorose dentária em escolares de Marinópolis, São Paulo

Daudt, Liane Esteves; Zechmaister, Débora; Portal, L.N. Desalvo; Neto, Eurico Camargo; Silla, Lúcia Mariano da Rocha; Giugliani, Roberto

doi:10.1590/s0102-311x2002000300032

Cited by 22 publications

(13 citation statements)

References 10 publications

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“…The overall frequency of HbS carriers in the sample was slightly lower than that observed in southern Brazil, a region that shares borders with Uruguay and where a carrier frequency of 1.2% has been reported for newborns (Daudt et al , 2002). In contrast, there was a greater difference between the frequency in the Uruguayan population in the present study and that in populations from northeastern Brazil, where there is a greater contribution from African populations and the frequency of HbS carriers ranges from 5.1% to 11.4% (Azevedo et al , 1980; Bandeira et al , 1999; Adorno et al , 2005).…”

Section: Discussioncontrasting

confidence: 71%

Frequency and spectrum of hemoglobinopathy mutations in a Uruguayan pediatric population

et al. 2013

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Hemoglobinopathies are the most common recessive diseases worldwide but their prevalence in Uruguay has not been investigated. In this study, 397 unrelated outpatient children from the Pereira Rosell Hospital Center (CHPR), as well as 31 selected patients with microcytic anemia and 28 β-thalassemia carriers were analyzed for hemoglobinopathies by using biochemical and molecular biology methods. Parametric and non-parametric methods were used to compare the hematological indices between groups of genotypes. Of the 397 patients in the first group, approximately 1% (0.76% HbS and 0.25% β-thalassemia) had a mutation in the HBB gene and 3.3% had β-thalassemia. These mutations had a heterogeneous distribution that varied according to individual ancestry. HbS was found exclusively in individuals with declared African ancestry and had a carrier frequency of 2.2%. The frequency of α-thalassemia carriers in outpatients of European and African ancestry was 1.2% and 6.5%, respectively. In contrast, the frequency of α-thalassemia carriers in patients with microcytic anemia was 25.8%, significantly higher (p < 0.01) than that observed in the sample as a whole and in Afro-descendants and Euro-descendants. Significant differences were observed in the hematological parameters between individuals with thalassemia genotypes and those with a normal genotype. These results indicate that hemoglobinopathies are a relevant health problem in Uruguay.

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Section: Discussioncontrasting

confidence: 71%

Frequency and spectrum of hemoglobinopathy mutations in a Uruguayan pediatric population

et al. 2013

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“…Fluorosis was observed in cities with and without public water fluoridation supply, which is most likely the result of alternative mechanisms of fluoride ingestion during the tooth formation period. The most prevalent fluorosis levels in the present study were "very light" and "light", which corroborated previous reports (11)(12)(13). Fluorosis occurred in cities without water fluoridation, which suggest exposure to others sources of fluoride, such as dentifrices, mouth rinses, and polivitamins (12).…”

Section: Discussionsupporting

confidence: 92%

“…The most prevalent fluorosis levels in the present study were "very light" and "light", which corroborated previous reports (11)(12)(13). Fluorosis occurred in cities without water fluoridation, which suggest exposure to others sources of fluoride, such as dentifrices, mouth rinses, and polivitamins (12). A lack of knowledge regarding these alternative fluoride sources and the adverse effects of fluoride due to excessive ingestion were shown to be important factors in the occurrence of fluorosis.…”

Section: Discussionsupporting

confidence: 91%

“…The survey of São Paulo State Population Oral Health Conditions in 1998 demonstrated that the average DFMT for 12 year-old children declined from 6.47 in 1986 to 3.72 in 1998 and 2.5 in 2002. Epidemiological surveys in Brazil have shown a decrease in dental caries and an increase in dental fluorosis (10), particularly fluorosis at light and very light levels (11,12). The manifestations associated with dental fluorosis are related to the exposure of the tooth germ to high fluoride ion concentrations during the tooth formation period (13).…”

Section: Introductionmentioning

confidence: 99%

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A comparative analysis of caries and fluorosis among cities with and without public water supply fluoridation in São Paulo State, Brazil

Moimaz¹,

Costa²,

Silva³

et al. 2010

Rev. odonto ciênc. (Online)

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Purpose: This population-based, cross-sectional study aimed to record the DMFT index for 12 year-old children with dental caries and fluorosis levels in cities with and without public water supply fluoridation.Methods: From the 101 municipalities belonging to the Health Regional Department XV (DRS-XV-SJRP) of the São Paulo state in the Southeast region of Brazil, 85 cities were selected after exclusion of those with incomplete data and less than ten years of fluoridation treatment in 2004. The criteria adopted for the assessment of dental caries and fluorosis levels were based on the guidelines published in the WHO Manual 4th edition. The data were analyzed using Fisher's exact tests at a significance level of 5%.Results: The prevalence of caries in 12 year-old children had no significant association with fluoridated water, and was considered "moderate" and "high" in cities without fluoridation and "low" and "moderate" in cities with fluoridation. A significant association was found between water fluoridation and fluorosis (P=0.001), but not between water fluoridation and the DMFT index (P=0.119).Conclusion: The prevalence of fluorosis was related to water fluoridation in this study. However, fluorosis was also observed in non-fluoridated cities, which may result from fluoride intake through other sources. Resultados: A prevalência de cárie aos 12 anos não teve associação significativa com a água fluoretada e foi considerada "moderada" e "alta" em municípios sem fluoretação e "baixa" e "moderada" nos municípios com fluoretação. A água fluoretada teve associação significativa com fluorose (P=0,001) mas não com o índice CPO-D (P=0,119).Conclusão: Houve associação entre prevalência de fluorose e água fluoretada, mas a fluorose também foi observada em municípios sem fluoretação, possivelmente pelo flúor existente nas diversas fontes de ingestão.

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“…Research conducted in the Gaza Strip, in the Palestinian Territories, showed that 61% of the collections occurred between the 11th and 17th day of life 18 . In Brazil, in Porto Alegre city, the average was 11 days; 19 in Sergipe State 17 days, with 50% of samples being collected in children older than 28 days; 20 in Campina Grande city, the average was 29.8 days, 21 and in Marília, São Paulo State, the average was 27 days 22 …”

Section: Discussionmentioning

confidence: 99%

Scope and efficiency of the newborn screening program in identifying hemoglobin S

Ivo

Araújo

Barbieri

et al. 2014

Revista Brasileira de Hematologia e Hemoterapia

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BackgroundIn 2001, the Brazilian Ministry of Health added hemoglobinopathies to the National Neonatal Screening Program to be implemented in three steps. In order to meet the proposed goals, it is crucial to establish periodic assessments of this program with the aim of monitoring its implementation.ObjectiveTo assess the scope and the efficiency of the stages of the National Newborn Screening Program in identifying hemoglobin S.MethodsA cross-sectional study was developed with the results of the heel prick test using the high performance liquid chromatography method for babies born in Mato Grosso do Sul from 2006 to 2010. The following variables were investigated: year, number of live births, total screening, coverage ratio, prevalence, time between the child birth and the blood collection; age at diagnosis; age at the time of the first consultation; and time between the diagnosis and the first appointment.ResultsOver the five years of the study, the mean coverage rate was 91.77%. The prevalences of hemoglobin FAS and hemoglobin FS were 1.65% and 0.011%, respectively. Blood samples from 43.48% of children were collected from the second to the seventh day. The age at diagnosis was within the first 28 days in 87.80% of the screened children. The lowest mean indices for the first consultation and the time between the diagnosis and the first appointment (58.8 and 46.4 days, respectively) occurred in 2010.ConclusionsThe scope of the National Neonatal Screening Program for hemoglobinopathies is good, with a large number of individuals being tested. Efficiency is a suitable indicator to assess the program steps. Three points are recommended: the training of the individuals involved, studies to assess the assistance provided to the affected child, and genetic counseling to the mothers.© 2014 Associação Brasileira de Hematologia, Hemoterapia e Terapia Celular. All rights reserved.

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Prevalência de fluorose dentária em escolares de Marinópolis, São Paulo

Cited by 22 publications

References 10 publications

Frequency and spectrum of hemoglobinopathy mutations in a Uruguayan pediatric population

Frequency and spectrum of hemoglobinopathy mutations in a Uruguayan pediatric population

A comparative analysis of caries and fluorosis among cities with and without public water supply fluoridation in São Paulo State, Brazil

Scope and efficiency of the newborn screening program in identifying hemoglobin S

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