Aspects of gastric cancer epidemiology with special reference to Latin America and Brazil

Muñóz, Núbia

doi:10.1590/s0102-311x1997000500013

Cited by 4 publications

(4 citation statements)

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“…High salt intake has been considered an important causative factor for many years [14,15]. However, salt consumption has been reduced in many countries, probably as a result of public health campaigns and improvements in food preservation (refrigeration), leading to the decreased consumption of salty preserved foods [16,17]. Most consistently, adequate intake of fresh fruits and vegetables is associated with decreased risk [18,19].…”

Section: Etiological Hypothesesmentioning

confidence: 99%

The future of gastric cancer prevention

2004

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Despite advances in surgical treatment and chemotherapy, gastric cancer remains a major global health burden. The most recent estimates show that it is the fourth most common cancer and the second most common cause of cancer deaths worldwide. Various etiologic factors have been linked with the disease. It is widely accepted that Helicobacter pylori infection and high salt intake are positively associated with this neoplastic process. Controversial associations have been found with smoking or drinking habits. In contrast, there is convincing evidence that the adequate consumption of fresh fruits and vegetables reduces the risk of gastric cancer. Prevention intervention trials involving antioxidant supplements and anti-H. pylori treatment have shown beneficial effects in preventing the progression of pathologic changes in the gastric mucosa. On the other hand, recent advances related to differences in the genotypes of the bacteria and in human cytokine polymorphisms would allow the design and implementation of large-scale screening programs to identify subjects at the highest risk of gastric cancer. Curing the infection in such subjects and supplying adequate amounts of antioxidants should prevent a neoplastic outcome, and this intervention should be monitored by endoscopic surveillance.

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Section: Etiological Hypothesesmentioning

confidence: 99%

The future of gastric cancer prevention

2004

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“…No Brasil, entre 1980 e 1995, a tendência foi semelhante. Nenhum argumento explica este fenômeno completamente, mas é aceito que o efeito simultâneo da melhoria na preservação de alimentos, queda no consumo de alimentos salgados, e o aumento da ingestão de vegetais frescos e frutas possa, pelo menos parcialmente, ter contribuído para tal tendência 16 . Embora as taxas de mortalidade por câncer de estômago sejam mais altas nas regiões Sul e Sudeste, o declínio das taxas foi também mais intenso nestas duas regiões.…”

Section: Esultados Esultadosunclassified

Mortalidade por câncer no Brasil 1980-1995: padrões regionais e tendências temporais

Filho¹,

Moncau²

2002

Rev. Assoc. Med. Bras.

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Mortality rates by all cancers were heterogeneous in Brazil. The risk of death by cancer was higher in the Southern and Southeastern regions, but was decreasing in these regions, the more developed in the country. The other regions, less developed, had lower mortality rates by cancer, but the rates were on increase. From 1991 to 1995, it was observed the stability of mortality rates from tobacco related cancers, fact less perceived among females.

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“…Stomach cancer is the fourth most common malignant tumor in the world, and although numbers have fallen in recent years, mortality from this cause is still high (1)(2)(3). In Brazil, some studies have shown a reduction in mortality from stomach cancer since the 1980s (4,5), which can be attributed to improved eating habits, food preservation, and treatment of Helicobacter pylori infection (6,7).…”

Section: Introductionmentioning

confidence: 99%