Eficácia do florfenicol e da oxitetraciclina no controle de Aeromonas hydrophila em pacu (Piaractus mesopotamicus)

Carraschi, Silvia Patrícia; Cruz, Claudinei da; Neto, Joaquim Gonçalves Machado; Castro, Maria António; Bortoluzzi, Neida Lucas; Gírio, Ana Cristina Fausto

doi:10.1590/s0102-09352011000300007

Cited by 14 publications

(8 citation statements)

References 16 publications

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“…Certified standards of florfenicol were acquired from Sigma Aldrich (St. Louis, MO, USA). Nile tilapia were exposed to water containing florfenicol at a nominal concentration of 10 mg L −1 , which is equivalent to 1/100 of the LC50 ( Carraschi et al., 2011 ; OECD, 2012 ), which is the dose that fish famers commonly use in transport water to guarantee survival after transport ( Klein et al., 2013 ). Contaminated water from experimental aquariums were sampled (5 mL of water collected in the middle of the water column) for a quantitative description of florfenicol contamination.…”

Section: Methodsmentioning

confidence: 99%

“…Antibiotics are compounds that are administrated to control these fish diseases. In Brazil, two antimicrobials are used in aquaculture: florfenicol and oxytetracycline ( Andrade et al., 2017 ; Carraschi et al., 2011 ; Nunes et al., 2018 ). Florfenicol has been used in Brazil since 2007 ( Orlando et al., 2016 ) and is one of the most widely used in aquaculture throughout the world ( Norambuena et al., 2013 ).…”

Section: Introductionmentioning

confidence: 99%

“…Florfenicol is a veterinary drug that has been widely used to treat infections in fish due to its broad spectrum of action, which acts against both Gram-positive and negative bacteria such as Aeromonas salmonicida , A. hydrophyla , Flavobacterium psychrophilum , Yersinia ruckeri and Vibrio anguillarum ( Carraschi et al., 2011 ). The mechanism of action of this antibiotic is based on its ability to inhibit protein synthesis by binding to the 50S fraction of the bacterial ribosome ( Orlando et al., 2016 ).…”

Section: Introductionmentioning

confidence: 99%

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Evaluation of health and environmental risks for juvenile tilapia (Oreochromis niloticus) exposed to florfenicol

Shiroma

Soares

Cardoso

et al. 2020

Heliyon

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Intensive fish cultivation has a high incidence of infection, which is often controlled by administering antibiotics. Florfenicol (FF) is one of the two antimicrobial drugs permitted for aquaculture in Brazil. Due to their intensive use, potentially harmful effects on aquatic organisms are of great concern. In this sense, we investigated whether the presence of FF in cultivation water could change the health parameters of Nile tilapia. For this, we evaluated hemoglobin, hematocrit, mean corpuscular hemoglobin (MCHC) concentration, mean corpuscular volume (MCV), total plasma protein (TPP), number of circulating red blood cells and leukocytes, as lipid peroxidation levels, catalase activity and glutathione S-transferase activity of fish exposed to 11.72 mg L −1 of FF in water for 48 h. The fish were divided into two groups: Nile tilapia in water with FF or without FF (control). Exposure to FF in cultivation water for a short period didn't change the hematological variables analyzed, but caused changes in liver ROS (Reactive oxygen species) markers of the Nile tilapia, which was revealed by lipid peroxidation levels, catalase activity, and glutathione S-transferase. The 48h exposure period was enough to induce oxidative stress in hepatocytes, causing cellular oxidative damage. Therefore, the antibiotic florfenicol may cause toxicity to organisms and aquatic ecosystems, even at a sublethal concentrations near 1/100 LC50-48h for fish species.

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Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Evaluation of health and environmental risks for juvenile tilapia (Oreochromis niloticus) exposed to florfenicol

Shiroma

Soares

Cardoso

et al. 2020

Heliyon

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“…The survival was better in the treatment with florfenicol in the diet, which shows that concentration of antibiotic used in this experiment was effective for the maintenance survival suitable for the species (Carraschi et al 2011, Andrade et al 2017). According to Carraschi et al (2011), the antibiotic florfenicol supplied in the diet at the concentration of 10.0 mg kg -1 , provided greater survival in pacus (Piaractus mesopotamicus).…”

Section: Discussionmentioning

confidence: 50%

Probiotic, antibiotic and combinations in Nile tilapia juveniles culture

Ferreira

Amorim

Souza

et al. 2019

An. Acad. Bras. Ciênc.

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This study aimed to evaluate the effect of the commercial probiotic (Saccharomyces cerevisiae), antibiotic (florfenicol), and its combination for Nile tilapia culture. The experiment was arranged in a completely randomized design with five replications, and five treatments diets: Control: water and diet without additives; YD: yeast in the diet (1 g Kg-1); AW: antibiotic in the water (0.002 g L-1); AWYD: antibiotic in the water, and yeast in the diet (0.002 g L-1 and 1 g Kg-1); and AD: antibiotic in the diet (0.01 g kg-1). The growth parameters as total and standard length, weight, weight gain, biomass, Fulton's condition factor, specific growth rate and plasma cortisol of tilapia did not show the difference between the treatments. The survival rates and food conversion rate of fish were greater in treatment with florfenicol included in the diet. The commercial probiotic did not improve growth or survival. The administration of the antibiotic florfenicol in the water needs more studies. The inclusion of the antibiotic in the diet promotes growth and survival in Nile tilapia juvenile.

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“…are opportunistic microorganisms that frequently cause diseases in fish immunosuppressed by adverse environmental conditions, nutritional deficiencies, high stocking densities, excessive manipulation, prolonged transport and mechanical injuries, among others (Figueiredo & Leal, ). Some signs and symptoms associated with this bacteriosis are superficial lesions or ulcers on the skin, haemorrhagic spots along the body, distended abdomen and exophthalmos, and infection may even lead to mortality (Carraschi et al., ; Pavanelli, Eiras, & Takemoto, ).…”

Section: Introductionmentioning

confidence: 99%

Dietary addition of the essential oil from Lippia alba to Nile tilapia and its effect after inoculation with Aeromonas spp.

Souza

Costa

et al. 2018

Aquacult Nutr

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The objective of this study was to evaluate the effect of dietary addition of the essential oil from Lippia alba (EOLA) on growth performance, biochemical and haematological variables and survival after Aeromonas spp. infection of Nile tilapia juveniles (Oreochromis niloticus). Five diets were evaluated with increasing levels of EOLA (0.0 control; 0.25; 0.50; 1.0; and 2.0 ml/kg diet). After 45 days of feeding, the fish were infected with Aeromonas spp. followed by a 14-day period of observation. There was no mortality during growth assessment. The addition of 2.0 ml EOLA/kg diet improved feed conversion ratio and condition factor and increased lysozyme activity and haematocrit (Hct), and decreased plasma globulin levels compared to the control group. The survival of fish infected with Aeromonas spp. was higher in those fed with 2.0 ml EOLA/kg diet than in fish fed with 0.0-0.5 ml EOLA/kg diet. We concluded that the inclusion of 2.0 ml EOLA/kg diet is recommended for Nile tilapia juveniles, because it improved feed conversion, Hct and immunological activity, did not provoke metabolic changes, and increased survival after Aeromonas spp. infection. K E Y W O R D S feed conversion ratio, haematocrit, infection, lysozyme activity, Oreochromis niloticus, Survival S U PP O RTI N G I N FO R M ATI O N Additional supporting information may be found online in the Supporting Information section at the end of the article. How to cite this article: de Souza RC, de Souza EM, da Costa MM, Melo JFB, Baldisserotto B, Copatti CE. Dietary addition of the essential oil from Lippia alba to Nile tilapia and its effect after inoculation with Aeromonas spp.. Aquacult Nutr.

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Eficácia do florfenicol e da oxitetraciclina no controle de Aeromonas hydrophila em pacu (Piaractus mesopotamicus)

Abstract: Eficácia do florfenicol e da oxitetraciclina no controle de Aeromonas hydrophila em pacu (Piaractus mesopotamicus)[Efficacy of the florfenicol and of the oxytetracycline in the control in Aeromonas hydrophila in pacu (Piaractus mesopotamicus)]

Cited by 14 publications

References 16 publications

Evaluation of health and environmental risks for juvenile tilapia (Oreochromis niloticus) exposed to florfenicol

Evaluation of health and environmental risks for juvenile tilapia (Oreochromis niloticus) exposed to florfenicol

Probiotic, antibiotic and combinations in Nile tilapia juveniles culture

Dietary addition of the essential oil from Lippia alba to Nile tilapia and its effect after inoculation with Aeromonas spp.

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