Aspectos epidemiológicos, clínicos e hematológicos de 251 cães portadores de mórula de Ehrlichia spp. naturalmente infectados

Abstract

RESUMORealizou-se um estudo retrospectivo dos aspectos epidemiológicos, sinais clínicos, dados de exame físico e alterações hematológicas da erliquiose em 251 cães naturalmente infectados por Ehrlichia spp. Dos 4407 casos atendidos em hospital veterinário no período de janeiro de 2002 a dezembro de 2003, verificou-se que 251 cães eram portadores de mórula de Ehrlichia spp. em leucócitos de sangue periférico. Destes, 48 foram eliminados das avaliações por apresentarem patologias concomitantes. Nos 203 cães restantes, verificou-se que houve maior ocorrência em fêmeas (61,1%) e que a doença mantevese constante durante todo o período avaliado. Observou-se que 38% encontravam-se na faixa etária entre um e 23 meses e 58,6% eram de raça definida. As principais alterações clínicas observadas foram apatia, anorexia/hiporexia, vômito, secreção oculonasal e esplenomegalia. Cento e cinco cães apresentaram temperatura retal entre 38 e 39,5°C. As alterações observadas com maior frequência no hemograma foram anemia, predominando o tipo normocítica normocrômica (58,2%); desvio nuclear de neutrófilos para a esquerda (67%) e eosinopenia (58,1%).

Risk factors and clinical disorders of canine ehrlichiosis in the South of Bahia, Brazil

“…The main clinical signs observed during clinical examinations were similar to those described by Moreira et al (2003) and Borin et al (2009). Ehrlichia canis may cause variable signs, which make the diagnosis more challenging.…”

“…Early diagnosis of ehrlichiosis is important because this is an emerging zoonotic disease (PEREZ et al, 2006). The diagnostic techniques available include blood smears to view inclusions of corpuscles or morulae (BORIN et al, 2009), serum tests, especially Dot-ELISA and the indirect immunofluorescence assay (IFA) (TRAPP et al, 2006), and molecular techniques such as nested PCR (SOUZA et al, 2010).…”

Occurrence of Ehrlichia canis and Anaplasma platys in household dogs from northern Parana

“…One of the hematological alterations frequently observed in dogs diagnosed with CME is anemia, which is usually normocytic, normochromic, and nonregenerative, suggesting restricted or no bone marrow response (HARRUS et al, 1997;BULLA et al;BORIN et al 2009;GAUNT et al, 2010). These hematological alterations in this anemic disease are probably caused by the combined or isolated effects of the reactions induced by the monocyte-phagocyte system, cell lysis due to the action of the complement system, and suppression of erythropoiesis in the bone marrow are the mechanisms responsible for the table identified as anemic disease (MOREIRA et al, 2003).…”

Abortion and fetal death in bitches due anemia caused by vector-borne diseases

“…These pathogens may have caused weakness and consequently RF. Thrombocytopenia in dogs with leishmaniasis (C6), ehrlichiosis (C1, C7, C13), and anaplasmosis (C1, C7, C13, C19) is expected; however, RF was not previously described as a clinical sign (Borin et al, 2009). The presence of these pathogens induces anemia, which can increase the likelihood of RF.…”

“…The presence of these pathogens induces anemia, which can increase the likelihood of RF. Anemia has been associated with animals chronically infected with multisystemic diseases (anaplasmosis, ehrlichiosis, or leishmaniasis), and clinical signs vary with the severity of the disease and the presence of co-infections (Borin et al, 2009;Ferreira et al, 2014). Genetic diversity of E. canis strains can express different forms of hematological and clinical manifestations of the disease.…”