Nitrogenous metabolism in Thoroughbred and Arabian foals from birth to five months of age

Piccione, Giuseppe; Costa, Anna-Maria; Fazio, Francesco; Grasso, Fortunata; Caola, G.

doi:10.1590/s0102-09352006000400012

Cited by 6 publications

(3 citation statements)

References 13 publications

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“…40 Lastly, uric acid concentrations were lower in Thoroughbred and Arabian foals at birth than at 4 weeks of age. 41 In our population, this potential for age-related maturation of other antioxidant mechanisms is supported by the finding that, despite a decrease in plasma AA concentration, the foal's PAC gradually increased during the neonatal period. The explanation for the increased PAC is unlikely to be driven by ingestion of mare's milk, as this was found to contain lower concentrations of AA and retinols, and similar amounts of tocopherols, compared to colostrum.…”

Section: Discussionsupporting

confidence: 63%

Plasma ascorbic acid, antioxidant capacity, and reactive oxygen species in healthy foals

Migliorisi

Hart

Vaughn

et al. 2022

ajvr

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OBJECTIVE To describe ascorbic acid (AA) concentrations, plasma antioxidant capacity (PAC) and markers of oxidative stress, as measured by derivatives of reactive oxygen metabolites (dROMs), in healthy foals at birth and during the first month of life. SAMPLES Venous blood samples were collected from healthy Standardbred (n = 13) and Quarter Horse (n = 10) foals. Plasma AA, PAC, and dROMs were assessed at 3 to 12 hours, 3 days, and 1, 2, and 4 weeks of age. PROCEDURES AA was measured via high-performance liquid chromatography. PAC and dROMs were measured with a free radical analytical system. Comparisons of AA, PAC, and dROMs at different time points were assessed. RESULTS Mean ± standard deviation AA concentrations at 3 to 12 hours (44.7 ± 19.6 μmol/L; P ≤ .01), 1 (48.6 ± 22.5 μmol/L; P ≤ .001), and 2 weeks (41.8 ± 15.8 μmol/L; P ≤ .001) were higher than at 4 weeks of age (28.5 ± 12.7 μmol/L). Both PAC and dROMs significantly increased at different time points compared to 3 to 12 hours of age. CLINICAL RELEVANCE Healthy foals have higher plasma AA concentrations shortly after birth, which then gradually decrease throughout the first month of life, suggesting that AA may represent a key antioxidant in the postnatal period. The concurrent increase in PAC and dROMs suggests that dynamic development of oxidative balance occurs after birth in foals. Development of AA, PAC, and dROM reference ranges in healthy foals could be used to guide therapeutic interventions and monitor during disease states characterized by increased oxidative stress.

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Section: Discussionsupporting

confidence: 63%

Plasma ascorbic acid, antioxidant capacity, and reactive oxygen species in healthy foals

Migliorisi

Hart

Vaughn

et al. 2022

ajvr

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“…Nevertheless, fever (>39C°) only occurred in control foals. The decrease in heart and respiratory rates as well as rectal temperature over time in both groups was expected and resulted from normal ageing of the foals (Piccione and others 2006, Bernard and Barr 2011) as well as familiarisation with handling.…”

Section: Discussionmentioning

confidence: 80%

Rhodococcus equi hyperimmune plasma decreases pneumonia severity after a randomised experimental challenge of neonatal foals

2016

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“…Total proteins values in the neonatal phase of foals were lower compared to adults in the donkey (D'Alessandro et al, 2007) as well as in the horse (Bauer et al, 1985). In the horse the contemporary decrease of urea has been associated to growth requirements of the foal (Bauer et al, 1984;Piccione et al, 2006).…”

Section: Resultsmentioning

confidence: 99%

Values of Energetic, Proteic and Hepatic Serum Profiles in Neonatal Foals of the Martina Franca Donkey Breed

D’Alessandro

Casamassima²,

Palazzo³

et al. 2012

mjas

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The study aimed to investigate in neonatal donkey foals some serum parameters of the energetic (glucose, cholesterol, triglycerides) and proteic (total proteins, urea, albumine, creatinine) metabolism, and hepatic profile (GOT, GGT, alkaline phosphatase, AP, total bilirubin, GPT, LDH), at 12, 36, 60, 84, 108 hrs and 11 days after birth. The research concerned 10 donkey foals of the Martina Franca breed reared under natural conditions in Southern Italy. All foals, in good health conditions during the study, suckled regularly colostrum/milk from their mothers and were handled carefully. Blood was drawn in the morning from the jugular vein. Serum urea creatinine GPT and AP levels varied (0.05 > P < 0.01) with the age of the foals. Within the proteic profile, urea and creatinin levels were higher (0.05 > P < 0.01) at 12 hours after birth, as well as AP (0.05 > P < 0.01) and GPT (P < 0.05) within the hepatic profile. No differences were found for the energetic serum parameters. Significant correlations (0.05 > P < 0.01) were found between all the biochemical metabolities. The present study gives the first reference ranges for serum biochemical concentrations in the authochtonous Martina Franca donkey breed during the neonatal period, constituting basic knowledge for the husbandry system and welfare of foals.

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Nitrogenous metabolism in Thoroughbred and Arabian foals from birth to five months of age

Cited by 6 publications

References 13 publications

Plasma ascorbic acid, antioxidant capacity, and reactive oxygen species in healthy foals

Plasma ascorbic acid, antioxidant capacity, and reactive oxygen species in healthy foals

Rhodococcus equi hyperimmune plasma decreases pneumonia severity after a randomised experimental challenge of neonatal foals

Values of Energetic, Proteic and Hepatic Serum Profiles in Neonatal Foals of the Martina Franca Donkey Breed

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