Prevalência de adenomas colorretais em pacientes com história familiar para câncer colorretal

Zandoná, Bianca; Carvalho, Luciano Pinto de; Schimedt, Julia; Koppe, Daniela Cerqueira; Koshimizu, Ruy Takashi; Mallmann, Afonso Calil Mury

doi:10.1590/s0101-98802011000200006

Cited by 9 publications

(9 citation statements)

References 23 publications

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“…6,10 In the group with a positive family history for CRC (Group II), 21% had polyps detected, with no statistical difference vs. Group I. These results were similar to those described by Zandoná et al, 19 who evaluated patients with a family history of colorectal cancer compared with patients undergoing colonoscopy with a wide range of indications, showing a percentage of 18% of polyps in the group with a positive family history and 14% in the population with an indication for colonoscopic evaluation.…”

Section: Discussionsupporting

confidence: 87%

“…6,10 In an analysis of types of polyps in Groups I and II, our data were similar (37% and 45% of adenomatous polyps, respectively). Corroborating the results of this study, Zandoná et al 19 confirmed that there was no statistical difference in the prevalence of adenomatous polyps, when comparing patients with a positive family history for CRC vs. symptomatic patients and/or individuals with an indication for colonoscopy.…”

Section: Discussionsupporting

confidence: 83%

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Is prevalence of colorectal polyps higher in patients with family history of colorectal cancer?

Murad-Regadas

Bezerra

Peixoto

et al. 2015

Journal of Coloproctology

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Section: Discussionsupporting

confidence: 87%

Section: Discussionsupporting

confidence: 83%

Is prevalence of colorectal polyps higher in patients with family history of colorectal cancer?

Murad-Regadas

Bezerra

Peixoto

et al. 2015

Journal of Coloproctology

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“…Considerando que as regiões Sul e Sudeste são áreas mais desenvolvidas e industrializadas do Brasil, os aumentos da taxa de mortalidade e do número de óbitos nessas regiões podem estar relacionados aos fatores de risco presentes em países desenvolvidos. Essas diferenças geográficas podem ser atribuídas aos hábitos alimentares e a fatores ambientais que são impostos sobre um fundo de susceptibilidade genética (21,22) . O aumento nas taxas de mortalidade pode estar relacionado com os fatores de riscos associados a essa patologia, tais como idade maior que 50 anos, dieta com alto teor calórico, consumo de carnes vermelhas, sedentarismo, tabagismo e ingestão de álcool (9,12) .…”

Section: Discussionunclassified

Câncer colorretal na população brasileira: taxa de mortalidade no período de 2005-2015

Menezes

Ferreira

Faro

et al. 2016

RBPS

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Colorectal cancer in the Brazilian population: mortality rate in the 2005-2015 period Cáncer colorrectal de la población brasileña: tasa de mortalidad en el período 2005-2015 RESUMO Objetivo: Analisar a taxa de mortalidade por câncer colorretal no Brasil. Métodos: Trata-se de um estudo descritivo, retrospectivo, de série temporal e espacial, realizado no período de janeiro de 2005 a junho de 2015, com base nos dados do Sistema de Informação sobre Mortalidade. Para avaliar a tendência anual de óbitos por região, foi utilizado o teste de Mann-Kendall, e regressões lineares para avaliar o sentido de crescimento. O nível de significância adotado foi de 5%, sendo empregado o software R Core Team 2015. Resultados: A taxa de mortalidade no Brasil foi 7,98 óbitos/100 mil habitantes para o ano de 2014. Maiores taxas foram observadas nas regiões Sul e Sudeste. Quanto ao número de óbitos por sexo, prevaleceu o feminino em todas as regiões brasileiras, destacando-se a região Sudeste. Conclusão: O estudo do câncer colorretal tem sua importância a nível epidemiológico por demonstrar um aumento crescente nos índices de mortalidade. Descritores: Neoplasias Colorretais; Registros de Mortalidade; Mortalidade. ABSTRACT Objective: To analyze the colorectal cancer mortality rate in Brazil. Methods: Descriptive and retrospective spatial time series study conducted from January 2005 to June 2015 using data from the Mortality Information System. The annual trend of deaths by region was assessed using the Mann-Kendall test and linear regressions to evaluate the direction of the growth. The significance level was set at 5% and the software R Core Team 2015 was used. Results: The mortality rate in Brazil was 7.98 deaths/100,000 inhabitants for the year 2014. Higher rates were observed in the South and Southeast regions. Regarding the number of deaths by sex, the female gender prevailed in all Brazilian regions, especially in the Southeast region. Conclusion: The study of colorectal cancer is epidemiologically important as it demonstrates a steady increase in mortality rates. Descriptors: Colorectal Neoplasms; Mortality Registries; Mortality. RESUMEN Objetivo: Analizar la tasa de mortalidad por cáncer colorrectal en Brasil. Métodos: Se trata de un estudio descriptivo, retrospectivo, de serie temporal y espacial realizado entre enero de 2005 y junio de 2015 basado en datos del Sistema de Información sobre Mortalidad. Se utilizó la prueba de Mann-Kendall para valorar la tendencia anual de muertes por región y regresiones lineares para valorar el sentido de crecimiento. El nivel de significación adoptado fue del 5% a través del software R Core Team 2015. Resultados: La tasa de mortalidad en Brasil fue de 7,98 muertes/100 mil habitantes en 2014. Se observaron tasas más elevadas en las regiones del Sur y Sudeste del país. Hubo prevalencia del sexo femenino para el número de muertes por sexo en todas las regiones brasileñas principalmente en la región Sudeste. Conclusión: El estudio del cáncer colorrectal es importante a nivel epidemiológico porq...

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“…7,17 When polyps are detected in the colonoscopy, they should be removed to histological exam, regardless of their size or morphology. 18 Polypectomy reduces the incidence of colorectal cancer from 76% up to 90%. 2 We found and resected polyps in 13 out of 39 patients submitted to colonoscopy that previously presented a positive FOBT.…”

Section: Discussionmentioning

confidence: 99%

Association of fecal occult blood tests results with colonoscopic findings in a general hospital and validation of the screening test

Saraceni¹,

Azevedo²,

Almeida

et al. 2019

Journal of Coloproctology

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Globally, colorectal cancer is the third leading cause of cancer death among men and the second among women, corresponding to about 10% of all cancers. The Brazilian Ministry of Health and National Cancer Institute recommend the screening of colorectal cancer for people over 50 years-old with Fecal Occult Blood Test. Endoscopy is limited to patients with positive screening results. The aim of this study is to evaluate the incidence of malignant or premalignant lesions diagnosed by endoscopy in patients with positive or negative Fecal Occult Blood Test and assess the efficacy of Fecal Occult Blood Test to predict the finding of a malignant colorectal lesion. We carried out a cross-sectional study among patients with a Fecal Occult Blood Test result that were submitted to colonoscopy, in the same hospital, from March 2016 to July 2017. Sensitivity, specificity, positive and negative predictive value of Fecal Occult Blood Test compared to colonoscopy neoplastic findings was calculated. The total of 92 patients were enrolled, 52 (56.5%) were female, Fecal Occult Blood Test was positive in 42.4% of them and in 41 (44.6%) the colonoscopy showed abnormal findings. Polyps were the most frequent alteration, found in 20 patients (21.7%). Among the patients with polyps, 15 (16.3%) had neoplastic and 5 (5.4%) presented non-neoplastic polyps. The Fecal Occult Blood Test sensitivity for detection of neoplastic polyps was 66.7%, specificity 62.3%, positive predictive value 11% and negative predictive value was 94.2%. Considering the need for a screening method, Fecal Occult Blood Test showed to be an effective and reliable screening test that can be applied in public health programs to detect and prevent colorectal cancer.

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Prevalência de adenomas colorretais em pacientes com história familiar para câncer colorretal

Cited by 9 publications

References 23 publications

Is prevalence of colorectal polyps higher in patients with family history of colorectal cancer?

Is prevalence of colorectal polyps higher in patients with family history of colorectal cancer?

Câncer colorretal na população brasileira: taxa de mortalidade no período de 2005-2015

Association of fecal occult blood tests results with colonoscopic findings in a general hospital and validation of the screening test

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