Isotretinoína, depressão e suicídio

Madeira, Nuno; Santos, Tiago; Santos, Z.; Marques, António

doi:10.1590/s0101-60832012000200007

Cited by 3 publications

(3 citation statements)

References 8 publications

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“…Após a realização da pesquisa, observou-se que a porcentagem de pessoas do sexo feminino e masculino que procuraram pelo tratamento com a isotretinoína era de 60.33% feminino e 35.67% masculino. Esses dados se assemelham a pesquisa realizada por Madeira (2012), onde pesquisou a tolerabilidade da isotretinoína oral. Segundo esse autor, dos pacientes estudados, a maioria eram do sexo feminino, mostrando efetivamente que tanto homens quanto mulheres em proporções semelhantes procuram tratamento para acne.…”

Section: Figura 2 -Renda Mensal Média Dos Entrevistadosunclassified

“…A isotretinoína é comercializada com o nome de Roacutan®, sendo indicada para o tratamento de dermatoses, principalmente na acne nodulocística, na pitiríase rubro pilar, dermatite seborreica, psoríase postular, quimioprevenção do câncer, foliculites e quadros de acne resistentes a terapêuticas anteriores como antibióticos sistêmicos e agentes tópicos (MADEIRA, 2012).…”

Section: Introductionunclassified

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Avaliação do Conhecimento e o Uso de Isotretinoína com Alunos de uma Instituição de Ensino Superior do Município de Anápolis-Goiás

et al. 2021

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A isotretinoína pertence a um grupo de medicamentos chamados resinoides, relacionados à vitamina A, é conhecida por Roacutan®, sendo indicada em diversas dermatoses, principalmente na acne nodulocística. A sua ação baseia-se na diminuição do tamanho das glândulas sebáceas, diminuindo a produção de sebo, possibilitando a inibição da formação de comedões que ocorre pela ação do Propionibacterium acnes, responsável pelo processo inflamatório cutâneo e pela estimulação da produção de anticorpos. Este trabalho teve como objetivo avaliar o conhecimento e o uso de isotretinoína com alunos de uma instituição de ensino superior do município de Anápolis-Goiás. Foi desenvolvido uma pesquisa, com alunos de uma instituição de ensino superior do município de Anápolis, Goiás, através de questionário, semiestruturado. Observou-se que 66.67% dos alunos alcançaram o resultado pretendido e 33.33% não obtiveram êxito quanto ao tratamento, mostrando-se insatisfeitos com a Isotretinoína. Vale ressaltar também que todos os pacientes afirmaram estar cientes dos efeitos nocivos da isotretinoína durante o tratamento. Com a realização deste estudo é possível concluir que ambos os sexos procuram o uso da isotretinoína para tratamento. Desta forma, o estudo realizado buscou conhecer mais sobre o perfil dos usuários desse fármaco, juntamente com os efeitos adversos mais apresentados e se houve recidivas da acne após o uso. Palavras-chave: Retinóides. Roacutan. Pacientes. Abstract Isotretinoin belongs to a group of medicamen called resinoids, related to vitamin A, is known as Roacutan®, being indicated in several dermatoses, mainly in doducteistic acne. Its action is based on the decrease in the size of sebaceous glindils, decreasing the production of sebum, allowing the inhibition of the formation of comesn that occurs by the action of Propionibacterium acnes, responsible for the cutaneo inflamasorous process and the desatimization of antibody production. This study aimed to evaluate the knowledge and use of isotretinoin with alums from a higher education institution of the municipality of Anápolis-Goiás. A research was conducted with alums from a higher education institution in the municipality of Anápolis, Goiás, through a semi-structured questionnaire. It was observed that 66.67% of the students achieved the intended result and 33.33% were unsuccessful in treatment, showing to be dissatisfied with Isotretinoin. It is also worth mentioning that all pacients stated that they were aware of the harmful effects of isotretinoin during treatment. With the implementation of this esudo it is possible to agree that both sexes seek the use of isotretinoin for treatment. Thus, the edudo realiso sought to know more about the profile of users of this drug, along with the most presented adverse effects and whether there was a relapse of acne after use. Keywords: Retinoids. Roacutan. Patients.

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Section: Figura 2 -Renda Mensal Média Dos Entrevistadosunclassified

Section: Introductionunclassified

Avaliação do Conhecimento e o Uso de Isotretinoína com Alunos de uma Instituição de Ensino Superior do Município de Anápolis-Goiás

et al. 2021

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“…[18,23,24] There are warnings that some non-psychoactive drugs can have a side effect of suicidal ideation, like efavirenz, an antiretroviral used in HIV treatment, and isotretinoin, used in skincare treatments in teenagers and young adults with acne. [25,26] Concerning corticosteroids, used in high dosage for treating neuropsychiatric conditions in lupus patients, although they can be related to psychotic breaks, there is some controversy in the literature whether it is indifferent or can increase the risk of suicide, it seems that the worst problem is due to the withdraw process, when the drug can reach levels below the optimum for clinical management, causing suicidal ideation. [2,[27][28][29] Regarding taking a suicidal drug overdose, a large nationwide population-based case-control study was performed in Taiwan.…”

Section: Risk and Protective Factorsmentioning

confidence: 99%

Suicide risk in systemic lupus erythematosus: A narrative review

Barros¹,

Carvalho

2021

DCC

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Introduction: Despite the medical and scientific advances, the disease’s restrictions and the perception of personal and social losses related to its course reinforce fear and generate intense suffering in lupus patients. Psychiatric comorbidities, especially major depressive episodes, are highly prevalent during systemic lupus erythematosus. Among them, suicide is a behavior that is much more common than we believe.Objective: To perform a narrative review on suicidal behavior associated with systemic erythematosus lupus (SLE).Results: Studies have shown an increased risk of suicide among patients with chronic diseases and psychiatric disorders, especially depression. However, suicide cannot be attributed only to a higher prevalence of depression and other mental illnesses. Therefore, it is necessary to learn more about the suicide risk factors present in patients with lupus to work on secondary prevention and avoid the premature loss of lives and the additional suffering of families and surrounding communities. The coordination between the studies on suicidal behavior and its intricate network of individual and sociocultural factors and the studies on this multisystem autoimmune disease with a broad manifestation spectrum, lupus, creates new and essential field research.Conclusions: Non-psychiatrist office-based physicians, health clinics, or wards dedicated to the treatment of SLE should recognize and handle the suicide risk factors on their patients to reduce the suffering caused by this disease.

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Suicide risk in systemic lupus erythematosus: a narrative review

Barros¹,

Araújo²,

Carvalho

2020

cmbio

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Introduction: the restrictions imposed by the disease and the perception of personal and social losses related to its course, despite the medical and scientific advances, reinforce fear and generate intense suffering in lupus patients. Psychiatric comorbidities, especially major depressive episodes, are highly prevailing during the course of systemic lupus erythematosus. Among them, suicide is a behavior that is much more common then we believe. Objective: to perform a narrative review on suicidal behavior associated with systemic erythematosus lupus (SLE). Results: studies have shown an increased risk of suicide among patients with chronic diseases and psychiatric disorder, especially depression. However, suicide occurrence cannot be attributed only to a higher prevalence of depression and other mental illnesses. It is necessary to learn more about the suicide risk factors that can be present in patients with lupus to work on a secondary prevention, and avoid not only the premature loss of lives but also the additional suffering of families and surrounding communities. The coordination between the studies on suicidal behavior and its complex network of individual and sociocultural factors and the studies on this multisystem autoimmune disease with a wide manifestation spectrum, which is lupus, creates a new and important field of research. Conclusion: non-psychiatrist office-based physicians, health clinics, or wards dedicated to the treatment of SLE should be able to recognize and handle the suicide risk factors on their patients in order to reduce the suffering caused by this disease.

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Isotretinoína, depressão e suicídio

Cited by 3 publications

References 8 publications

Avaliação do Conhecimento e o Uso de Isotretinoína com Alunos de uma Instituição de Ensino Superior do Município de Anápolis-Goiás

Avaliação do Conhecimento e o Uso de Isotretinoína com Alunos de uma Instituição de Ensino Superior do Município de Anápolis-Goiás

Suicide risk in systemic lupus erythematosus: A narrative review

Suicide risk in systemic lupus erythematosus: a narrative review

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