Prevalência de diabetes mellitus em pacientes renais crônicos sob hemodiálise em Porto Alegre, Brasil

Burmeister, Jayme Eduardo; Mosmann, Camila Borges; Baú, Renata; Rosito, Guido A.

doi:10.1590/s0101-28002012000200003

Cited by 6 publications

(6 citation statements)

References 7 publications

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“…With regard to the prevalence of DM among ESKD patients, the national scenario was illustrated by the 2012 Brazilian Chronic Dialysis Census, 5 revealing that 28.5% of patients on dialysis treatment also have diabetes as an associated comorbidity, which is a slightly lower figure than was found in the present study (33.10%). A study conducted in 2009 in the South of Brazil by Burmeister et al 15 reported that 37.9% of the hemodialysis patients studied also had DM. These epidemiological data suggest that there are significant regional differences in DM rates among hemodialysis patients.…”

Section: Discussionmentioning

confidence: 97%

“…5 However, it should be acknowledged that DM associated with ESKD has been becoming increasingly predominant within the Brazilian epidemiological profile and if the trend continues it will reach worldwide prevalence rates in the next few years. 14,15 Considering the increasing role of diabetes mellitus as a cause of ESKD in our country, and the challenges involved in constructing AVFs in certain groups of patients, the primary objective of this study was to compare the mean duration of patency of occluded AVFs before this event, and the survival rates of arteriovenous fistulas constructed in patients with diabetes mellitus, with the same outcomes in patients who do not have diabetes mellitus, in patients given hemodialysis treatment at the Hospital Santa Casa de Misericórdia de Ponta Grossa (Parana, Brazil).…”

Section: Introductionmentioning

confidence: 99%

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Influência do diabetes mellitus sobre a perviedade da fístula arteriovenosa para hemodiálise

et al. 2015

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ResumoContextoA incapacidade das fístulas arteriovenosas (FAVs) atenderem aos quesitos mínimos para realização da hemodiálise (HD) corresponde a uma das maiores causas de morbidade nos pacientes em terapia renal substitutiva. Identificar os fatores de risco associados com a falência do acesso vascular é fundamental para o manejo e sucesso da terapia hemodialítica.ObjetivoComparar o tempo médio de patência e a sobrevida das fístulas arteriovenosas realizadas nos pacientes portadores de diabetes mellitus com pacientes não portadores de diabetes mellitus (DM) em HD.MétodosTrata-se de um estudo retrospectivo observacional, no qual foram observados os prontuários médicos de todos os pacientes em HD no Hospital Santa Casa de Misericórdia de Ponta Grossa, no período de fevereiro de 2014. Foram analisados dados clínicos referentes à confecção, manutenção e utilização das FAVs como adjuvante na terapia dialítica, comparando o tempo médio de patência das fístulas em uso para HD, bem como a sobrevida das FAVs ocluídas. Os pacientes selecionados foram divididos em dois grupos para comparação, conforme a presença ou ausência de DM.ResultadosOs indivíduos do Grupo DM apresentaram maior média de idade (59,97 ± 10,12), menor tempo de acompanhamento no serviço de hemodiálise (25,42 ± 21,03 meses), menor tempo médio até a oclusão da fístula arteriovenosa (9,03 ± 11,60 meses) e menor média de sobrevida dos acessos vasculares em 24 meses (50,25%).ConclusõesO estudo concluiu que para os pacientes diabéticos houve um menor tempo médio da patência das FAVs e menor taxa de sobrevida dos acessos em 24 meses.

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Section: Discussionmentioning

confidence: 97%

Section: Introductionmentioning

confidence: 99%

Influência do diabetes mellitus sobre a perviedade da fístula arteriovenosa para hemodiálise

et al. 2015

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“…Currently, diabetes, recognized as a socioeconomic disease, is considered one of the main causes for the appearance of kidney diseases in developed countries. Diabetic nephropathy is the main cause of CKD in the world and can lead to death 3 , 4 , 25 , 28 .…”

Section: Discussionmentioning

confidence: 99%

Experimental model of nephropathy associated with diabetes mellitus in mice

Silva

Corazza

et al. 2023

Acta Cir. Bras.

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Purpose: Nontransmissible chronic diseases, such as diabetes mellitus (DM) and nephropathy, affect a significant portion of the population, often treated due to injuries that require healing and regeneration. To create an experimental model of associated comorbidities, for healing and regeneration studies, protocols for induction of nephropathy by ischemia and reperfusion (I/R) and induction of DM by injection of streptozotocin (STZ) were associated. Methods: Sixty-four mice ( Mus musculus ), female, adult, Swiss strain, weighing approximately 20 g, were divided into four groups: G1: control (n = 24), G2: nephropathy group (N) (n = 7), G3, DM (n = 9), and G4: N+DM (n = 24). Arteriovenous stenosis (I/R) of the left kidney was performed as the first protocol. The animals received a hyperlipidemic diet for 7 days after the injection of STZ (150 mg/kg, via i.p.) and an aqueous glucose solution (10%) for 24 h. The animals in the G3 and G4 groups were observed for 14 days before receiving the diet and STZ. The evolution of nephropathy was observed using a urine test strip and the DM, through the analysis of blood glucose with a reagent strip on a digital monitor. Results: The ischemic induction protocols of nephropathy and DM with STZ, associated, were sustainable, low-cost, and without deaths. There were alterations compatible with initial renal alterations, in the first 14 days, such as increased urinary density, pH alteration, presence of glucose, proteins and leukocytes, when compared to the control group. DM was confirmed by the presence of hyperglycemia 7 days after induction and its evolution after 14 days. The animals in the G4 group showed constant weight loss when compared to the other groups. It was possible to observe morphological alterations in the kidneys submitted to I/R, regarding coloration, during surgery and after the end of the observation period, in the volume and size of the left kidney, when compared to the contralateral kidney. Conclusions: It was possible to induce nephropathy and DM associated in the same animal, in a simple way, confirmed with rapid tests, without losses, providing a basis for future studies.

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“…Regarding the presence of DM, it is highlighted that it is the main cause of ARF, because persistent hyperglycemia causes damage to nephrons, leading to a diabetic nephropathy condition and reverberating on renal function failure; thus, the use of contrast presents a high risk of evolving to ARF and even death. Patients with DM require attention when performing procedures with contrast, needing evaluation of the renal function in order to minimize severe renal damage [36].…”

Section: Discussionmentioning

confidence: 99%

Risk Factors for Acute Renal Failure after Cardiac Catheterization Most Cited in the Literature: An Integrative Review

Sardinha

Simor

Moura

et al. 2020

IJERPH

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Acute renal failure (ARF) represents 17% of the complications of cardiac catheterization (CC), with a high death rate and longer hospitalization time. The objective of this review is to describe the most cited risk factors for acute kidney failure in the literature. It is a descriptive and exploratory Integrative Literature Review (ILR) with a qualitative approach, using articles published in the Latin American and Caribbean Health Sciences Literature (LILACS) and PubMed databases between the years of 2009 and 2019 in English, Portuguese, and Spanish, including original articles, reviews, and case studies. The search was made using the following descriptors: cardiac catheterism, kidney diseases, risk factors, coronary catheterization, acute kidney injury, acute renal failure, and nephropathies. The organization and analysis of the data was through the application of a questionnaire that was structured by the authors, and the results are presented in a table. For the final sample, 10 articles were sought. The highlighted factors were being elderly, hypertensive, and diabetic; having previous kidney disease, hypotension, heart failure, higher contrast volumes, and types; the use of non-steroidal anti-inflammatory drugs associated to other risk factors; and atrial fibrillation. Atrial fibrillation was the main finding, which has recently been documented. The identification of risk factors provides health professionals with information to plan measures to prevent ARF, minimizing complications, length of stay, and mortality.

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Prevalência de diabetes mellitus em pacientes renais crônicos sob hemodiálise em Porto Alegre, Brasil

Abstract: The prevalence of DM among chronic HD patients in Porto Alegre is higher than what was previously published as a cause of CRF in the country, which indicates the possibility that this etiology of CRF may have been underestimated.

Cited by 6 publications

References 7 publications

Influência do diabetes mellitus sobre a perviedade da fístula arteriovenosa para hemodiálise

Influência do diabetes mellitus sobre a perviedade da fístula arteriovenosa para hemodiálise

Experimental model of nephropathy associated with diabetes mellitus in mice

Risk Factors for Acute Renal Failure after Cardiac Catheterization Most Cited in the Literature: An Integrative Review

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