Indução de resposta inflamatória sistêmica e espessamento de artérias subepicárdicas em um modelo animal de uremia

Carmona, Anthony Augusto; Rigon, Bruno Gleizer da Silva; Barroso, Michel Peter Barchik Salvatierra; Hauser, Aline Borsato; Précoma, Dalton Bertolim; Bucharles, Sérgio Gardano Elias; Noronha, Lúcia de; Pécoits-Filho, Roberto

doi:10.1590/s0101-28002011000400004

J. Bras. Nefrol.

2011

DOI: 10.1590/s0101-28002011000400004

|View full text |Cite

Indução de resposta inflamatória sistêmica e espessamento de artérias subepicárdicas em um modelo animal de uremia

Anthony Augusto Carmona¹,

Bruno Gleizer da Silva Rigon²,

Michel Peter Barchik Salvatierra Barroso³

et al.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2022

Publication Types

Select...

Article1

Relationship

Self Cite0

Independent1

Authors

Journals

Cited by 1 publication

References 21 publications

(24 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

Uremic Toxins and Cardiovascular Risk in Chronic Kidney Disease: What Have We Learned Recently beyond the Past Findings?

Chamieh

Liabeuf

Ziad³

2022

Toxins

View full text Add to dashboard Cite

Patients with chronic kidney disease (CKD) have an elevated prevalence of atheromatous (ATH) and/or non-atheromatous (non-ATH) cardiovascular disease (CVD) due to an array of CKD-related risk factors, such as uremic toxins (UTs). Indeed, UTs have a major role in the emergence of a spectrum of CVDs, which constitute the leading cause of death in patients with end-stage renal disease. The European Uremic Toxin Work Group has identified over 100 UTs, more than 25 of which are dietary or gut-derived. Even though relationships between UTs and CVDs have been described in the literature, there are few reviews on the involvement of the most toxic compounds and the corresponding physiopathologic mechanisms. Here, we review the scientific literature on the dietary and gut-derived UTs with the greatest toxicity in vitro and in vivo. A better understanding of these toxins’ roles in the elevated prevalence of CVDs among CKD patients might facilitate the development of targeted treatments. Hence, we review (i) ATH and non-ATH CVDs and the respective levels of risk in patients with CKD and (ii) the mechanisms that underlie the influence of dietary and gut-derived UTs on CVDs.

show abstract

Uremic Toxins and Cardiovascular Risk in Chronic Kidney Disease: What Have We Learned Recently beyond the Past Findings?

Chamieh

Liabeuf

Ziad³

2022

Toxins

View full text Add to dashboard Cite

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

hi@scite.ai

334 Leonard St

Brooklyn, NY 11211

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Indução de resposta inflamatória sistêmica e espessamento de artérias subepicárdicas em um modelo animal de uremia

Cited by 1 publication

References 21 publications

Uremic Toxins and Cardiovascular Risk in Chronic Kidney Disease: What Have We Learned Recently beyond the Past Findings?

Uremic Toxins and Cardiovascular Risk in Chronic Kidney Disease: What Have We Learned Recently beyond the Past Findings?

Contact Info

Product

Resources

About