Insuficiência renal aguda nefrotóxica: prevalência, evolução clínica e desfecho

Pinto, Patricia; Carminatti, Moisés; Lacet, Thiago Bento de Paiva; Rodrigues, Dominique Fonseca; Nogueira, Luiza O.; Bastos, Marcus Gomes; Fernandes, Natália

doi:10.1590/s0101-28002009000300003

Cited by 8 publications

(10 citation statements)

References 26 publications

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“…The medications used in the treatment of the diseases with higher prevalence in this study were antibiotics, diuretics and antihypertensives and ACEI inhibitors. According to the literature, these drugs can enhance renal alterations in patients with RF, or may even lead to the development of the disease ( 3 , 12 ) .…”

Section: Discussionmentioning

confidence: 99%

Predictive factors for renal failure and a control and treatment algorithm

Cerqueira

Tavares

Machado

2014

Rev. Latino-Am. Enfermagem

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Objectives to evaluate the renal function of patients in an intensive care unit, to identify the predisposing factors for the development of renal failure, and to develop an algorithm to help in the control of the disease. Method exploratory, descriptive, prospective study with a quantitative approach.Results a total of 30 patients (75.0%) were diagnosed with kidney failure and the main factors associated with this disease were: advanced age, systemic arterial hypertension, diabetes mellitus, lung diseases, and antibiotic use. Of these, 23 patients (76.6%) showed a reduction in creatinine clearance in the first 24 hours of hospitalization. Conclusion a decline in renal function was observed in a significant number of subjects, therefore, an algorithm was developed with the aim of helping in the control of renal failure in a practical and functional way.

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Section: Discussionmentioning

confidence: 99%

Predictive factors for renal failure and a control and treatment algorithm

Cerqueira

Tavares

Machado

2014

Rev. Latino-Am. Enfermagem

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“…A tabela 5 destaca que 46% dos enfermeiros afirmam que realizam o controle do ajuste das doses dos antibióticos dos pacientes com IRA. Um estudo demonstrou que em 87% dos tratamentos farmacológicos possuíam antibióticos nefrotóxicos (21) .…”

Section: Discussionunclassified

Levantamento do conhecimento dos enfermeiros sobre injúria renal aguda em unidades de internação e unidades de terapia intensivo adulto / Survey of nurses’ knowledge about acute kidney injury in inpatient unit and adult intensive care unit

Silva

Santos

2020

Arq Med Hosp Fac Cienc Med Santa Casa São Paulo

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Objetivo: Levantar o conhecimento do enfermeiro sobre Injúria renal aguda em unidades de internação e unidades de terapia intensiva adulto. Método: Trata-se de um estudo exploratório, descritivo, de corte transversal, com análise de discurso segundo o referencial teórico de Bardin. realizado em um hospital na região central da cidade de São Paulo, com 33 enfermeiros. Resultados: Os participantes do estudo são predominantemente do sexo feminino (94%). A idade média dos participantes foi de 35,8 anos (DP 12,21anos). Dos 33 enfermeiros, 34% graduaram-se no período de 2016 a 2019 e 24% de 2011 a 2015. Dos participantes que possuem especialização, 29% em UTI. Em relação ao entendimento sobre Injúria Renal Aguda (IRA), pouco mais da metade dos enfermeiros responderam de forma condizente com a definição estabelecida na literatura, 55% descreveram que a importância de detectar precocemente a IRA é para se evitar a doença renal crônica, quando questionados sobre as complicações da IRA, o distúrbio hidroeletrolítico apareceu em 19% das respostas e as alterações cardíacas/circulatórias apareceram em 18% e 46% colocaram que se preocupava em verificar as doses dos antibióticos estava ajustadas em caso de IRA. Conclusão: Existe a necessidade de capacitação dos enfermeiros e equipe de enfermagem para alinhar os conceitos, sinais e sintomas, complicações e intervenções para o manejo da IRA em pacientes críticos ou não, melhorando os desfechos e minimizando a morbimortalidade. Palavras chave: Lesão renal aguda, Enfermeiras e Enfermeiros, Enfermagem, Unidades hospitalares, Unidades de terapia intensiva, Conhecimento ABSTRACTObjective: To raise nurses’ knowledge about acute kidney injury in hospitalization units and adult intensive care units. Methodology: This is an exploratory, descriptive, cross-sectional study, with analysis of the according to Bardin’s speech, conducted in a hospital in the central region of São Paulo, with 33 nurses. Results: The study participants are predominantly female (94%). The average age of participants was 35.8 years (SD 12.21 years). Of the 33 nurses, 34% graduated from 2016 to 2019 and 24% from 2011 to 2015. Of the participants with specialization, 29% in ICU. Regarding the understanding of Acute Kidney Injury (AKI), just over half of nurses responded in a manner consistent with the definition established in the literature, 55% described that the importance of early detection of AKI is to prevent chronic kidney disease when asked about the complications of AKI, hydroelectrolytic disorder appeared in 19% of responses, and cardiac / circulatory changes in 18%, and 46% stated that they were concerned to verify that antibiotic doses were adjusted in case of AKI. Conclusion: There is a need for training of nurses and nursing staff to align the concepts, signs and symptoms, complications and interventions for the management of AKI in critically and non-critically ill patients, improving outcomes and minimizing morbidity and mortality.Keywords: Acute kidney injury, Nurses, Nursing, Hospital units, Intensive care units, Knowledge

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“…AKI in critically ill patients has a prevalence varying from 20 to 30%, and dialysis is required in around 60% of cases. 7,8 In pregnancy, AKI is still not well studied, and its determinant factors should be better investigated. It is estimated that AKI occur in 1 out of 10,000-20,000 pregnancies in developed countries.…”

Section: Discussionmentioning

confidence: 99%

Acute kidney injury in critically ill obstetric patients: a cross-sectional study in an intensive care unit in Northeast Brazil

Silva¹,

Saintrain²,

Castelo³

et al. 2017

Jornal Brasileiro De Nefrologia

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Lesão renal aguda em pacientes obstétricas gravemente doentes: um estudo transversal em uma unidade de terapia intensiva do nordeste do Brasil Introdução: A lesão renal aguda (LRA) é uma complicação ainda pouco estudada no contexto das pacientes obstétricas, que está associada com aumento da mortalidade. Objetivo: Investigar a frequência e os fatores de risco da LRA entre pacientes obstétricas. Métodos: Foi realizado estudo transversal com todas as pacientes admitidas em uma unidade de terapia intensiva (UTI) devido a complicações obstétricas em Fortaleza, Brasil, no período de janeiro de 2012 a dezembro de 2014. LRA foi definida de acordo com o critério AKIN. Resultados: Foram incluídas 389 pacientes, com idade entre 13 e 45 anos. As principais causas de admissão na UTI foram síndromes hipertensivas da gestação (54,5%), hemorragia e choque hemorrágico (12,3%), cardiopatias (9,0%), insuficiência respiratória (8,2%) e sepse (5,4%). LRA foi encontrada em 92 casos (24%), e esta foi a complicação mais frequente. A mortalidade geral foi de 7,5%, e a mortalidade por LRA foi de 21% (p = 0,0007). Na análise multivariada, os fatores de risco para LRA foram parto cesariano (IC 95% = 0,23-0,85, p = 0,01) e plaquetopenia (IC 95% = 1,50-4,36, p = 0,001). LRA foi um fator de risco independente para óbito (OR = 6,64, IC 95% = 3,11-14,15, p < 0,001). Conclusão: LRA foi a complicação mais frequente em pacientes obstétricas gravemente doentes e esteve associada com aumento da mortalidade. A maioria dos casos esteve associada às síndromes hipertensivas da gravidez, que são complicações passíveis de tratamento durante o pré-natal. ResumoPalavras-chave: gravidez; Insuficiência renal; mortalidade; unidades de terapia intensiva. Introduction: Acute kidney injury (AKI)is a complication still poorly studied in the setting of obstetric patients, which is associated with increased mortality. Objective: The aim of this study was to investigate the frequency and risk factors of AKI among critically ill obstetric patients. Methods: A cross-sectional study was conducted with all patients admitted to an intensive care unit (ICU) due to obstetric complications, in Fortaleza, Brazil, in the period between January 2012 and December 2014. AKI was defined according to AKIN criteria. Results: A total of 389 patients were included, aged between 13 and 45 years. The main causes of ICU admission were pregnancy-related hypertensive syndromes (54.5%), hemorrhage and hemorrhagic shock (12.3%), heart diseases (9.0%), respiratory insufficiency (8.2%) and sepsis (5.4%). AKI was found in 92 cases (24%), and this was the most frequent complication. General mortality was 7.5%, and mortality due to AKI was 21% (p = 0.0007). In the multivariate analysis, risk factors for AKI were cesarian delivery (95% CI = 0.23-0.85, p = 0.01) and thrombocythopenia (95% CI = 1.50-4.36, p = 0.001). AKI was an independent risk factor for death (OR = 6.64, 95% CI = 3.11-14.15, p < 0.001). Conclusion: AKI was the main complication among critically ill obstetric patients and it was a...

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Insuficiência renal aguda nefrotóxica: prevalência, evolução clínica e desfecho

Cited by 8 publications

References 26 publications

Predictive factors for renal failure and a control and treatment algorithm

Predictive factors for renal failure and a control and treatment algorithm

Levantamento do conhecimento dos enfermeiros sobre injúria renal aguda em unidades de internação e unidades de terapia intensivo adulto / Survey of nurses’ knowledge about acute kidney injury in inpatient unit and adult intensive care unit

Acute kidney injury in critically ill obstetric patients: a cross-sectional study in an intensive care unit in Northeast Brazil

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