Reference values for lung function tests: III. Carbon monoxide diffusing capacity (transfer factor)

Neder, J. Alberto; Andreoni, Solange; Peres, Celeide Pinto Aguiar; Nery, Luíz Eduardo

doi:10.1590/s0100-879x1999000600008

Cited by 134 publications

(92 citation statements)

References 17 publications

(25 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Observed values were compared with Brazilian standards. 19,20 All these pulmonary function measurements were executed in Visits 2 and 3 previous to the exercise test (before and 20 min after inhalation of salbutamol, 400 g via metered-dose inhaler) and immediately afterward. IC measures before and after exercise were done to track DH.…”

Section: Methodsmentioning

confidence: 99%

Effects of Expiratory Positive Airway Pressure on Dynamic Hyperinflation During Exercise in Patients With COPD

et al. 2012

View full text Add to dashboard Cite

Section: Methodsmentioning

confidence: 99%

Effects of Expiratory Positive Airway Pressure on Dynamic Hyperinflation During Exercise in Patients With COPD

et al. 2012

View full text Add to dashboard Cite

“…7), and f) cardiopulmonary exercise tests on a cycle ergometer (a square-wave protocol at 25 W for subject familiarization and, after 1 h, a maximal ramp-incremental exercise test). On a different day, g) total and regional body composition was evaluated by dual energy X-ray absorptiometry (DEXA) and h) knee strength measured by isokinetic dynamometry.…”

Section: Protocolmentioning

confidence: 99%

Reference values for lung function tests: II. Maximal respiratory pressures and voluntary ventilation

Neder

Andreoni

Lerario

et al. 1999

Braz J Med Biol Res

Self Cite

761

647

View full text Add to dashboard Cite

The strength of the respiratory muscles can be evaluated from static measurements (maximal inspiratory and expiratory pressures, MIP and MEP) or inferred from dynamic maneuvers (maximal voluntary ventilation, MVV). Although these data could be suitable for a number of clinical and research applications, no previous studies have provided reference values for such tests using a healthy, randomly selected sample of the adult Brazilian population. With this main purpose, we prospectively evaluated 100 non-smoking subjects (50 males and 50 females), 20 to 80 years old, selected from more than 8,000 individuals. Gender-specific linear prediction equations for MIP, MEP and MVV were developed by multiple regression analysis: age and, secondarily, anthropometric measurements explained up to 56% of the variability of the dependent variables. The most cited previous studies using either Caucasian or non-Caucasian samples systematically underestimated the observed values of MIP (P<0.05). Interestingly, the self-reported level of regular physical activity and maximum aerobic power correlates strongly with both respiratory and peripheral muscular strength (knee extensor peak torque) (P<0.01). Our results, therefore, provide a new frame of reference to evaluate the normalcy of some useful indexes of respiratory muscle strength in Brazilian males and females aged 20 to 80.

show abstract

“…DL,CO was measured by the modified Krogh technique (PF-DX System; Medical Graphics Corporation). Absolute values were compared with theoretical values for the adult Brazilian population [13][14][15]. Arterial blood samples were obtained from radial artery puncture in standard anaerobic conditions (ABL 330; Radiometer, Copenhagen, Denmark).…”

Section: Pulmonary Function Testsmentioning

confidence: 99%

A step test to assess exercise-related oxygen desaturation in interstitial lung disease

Corso

Duarte²,

Neder³

et al. 2006

European Respiratory Journal

102

View full text Add to dashboard Cite

A 6-min step test (6MST) may constitute a practical method for routinely assessing effort tolerance and exercise-related oxyhaemoglobin desaturation (ERD) in the primary care of patients with interstitial lung disease.In total, 31 patients (19 males) with idiopathic pulmonary fibrosis (n525) and chronic hypersensitivity pneumonia were submitted, on different days, to two 6MSTs. Physiological responses were compared with those found on maximal and submaximal cycle ergometer tests at the same oxygen uptake (V9O 2 ). Chronic breathlessness was also determined, as measured by the baseline dyspnoea index (BDI).Responses to 6MST were highly reproducible: 1.3¡2.0 steps?min -1 , ¡5 beats?min -1 (cardiac frequency), ¡50 mL?min -1 (V9O 2 ), ¡7 L?min -1 (minute ventilation) and ¡2% (arterial oxygen saturation measured by pulse oximetry (Sp,O 2 )). The number of steps climbed in 6 min was correlated to peak V9O 2 and the BDI. There were significant associations among the tests in relation to presence (change in Sp,O 2 between rest and exercise o4%) and severity (Sp,O 2 ,88%) of ERD. Four patients, however, presented ERD only in response to 6MST. Resting diffusing capacity of the lung for carbon monoxide and alveolar-arterial oxygen tension difference were the independent predictors of the number of steps climbed. A single-stage, self-paced 6-min step test provided reliable and reproducible estimates of exercise capacity and exercise-related oxyhaemoglobin desaturation in interstitial lung disease patients.

show abstract

Reference values for lung function tests: III. Carbon monoxide diffusing capacity (transfer factor)

Cited by 134 publications

References 17 publications

Effects of Expiratory Positive Airway Pressure on Dynamic Hyperinflation During Exercise in Patients With COPD

Effects of Expiratory Positive Airway Pressure on Dynamic Hyperinflation During Exercise in Patients With COPD

Reference values for lung function tests: II. Maximal respiratory pressures and voluntary ventilation

A step test to assess exercise-related oxygen desaturation in interstitial lung disease

Contact Info

Product

Resources

About