Nanotechnology: meeting the future of Veterinary Parasitology Research

Cruz, Amílcar Arenal; Molento, Marcelo Beltrão

doi:10.1590/s0100-736x2015001000004

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Neurocysticercosis (Ncc)1

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2016

2023

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Cited by 9 publications

(1 citation statement)

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“…Moreover the effectiveness of phytotherapeutic products can be improved, like the recent treatment of antiparasitic silver nano-particles using Cissus quadrangularis against Hippobosca aculata and Rhipicephalus (Boophilus) microplus [42]. Nano-devices also help veterinarians to suggest a correct health management [43]. In Cuba and Brazil some project are currently running using nanopeptides as a preliminary test against ruminant helminths (Haemonchus contortus and Fasciola hepatica).…”

Section: Neurocysticercosis (Ncc)mentioning

confidence: 99%

Immunodiagnosis Tools for Parasitic Diseases

Deepak¹,

Ld²

2016

J Microb Biochem Technol

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Section: Neurocysticercosis (Ncc)mentioning

confidence: 99%

Immunodiagnosis Tools for Parasitic Diseases

Deepak¹,

Ld²

2016

J Microb Biochem Technol

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Drug discovery technologies: Caenorhabditis elegans as a model for anthelmintic therapeutics

Sepúlveda‐Crespo

Reguera

Rojo-Vázquez

et al. 2020

Medicinal Research Reviews

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Helminthiasis is one of the gravest problems worldwide. There is a growing concern on less available anthelmintics and the emergence of resistance creating a major threat to human and livestock health resources. Novel and broad‐spectrum anthelmintics are urgently needed. The free‐living nematode Caenorhabditis elegans could address this issue through automated high‐throughput technologies for the screening of large chemical libraries. This review discusses the strong advantages and limitations for using C elegans as a screening method for anthelmintic drug discovery. C elegans is the best model available for the validation of novel effective drugs in treating most, if not all, helminth infections, and for the elucidation the mode of action of anthelmintic candidates. This review also focuses on available technologies in the discovery of anthelmintics published over the last 15 years with particular attention to high‐throughput technologies over conventional screens. On the other hand, this review highlights how combinatorial and nanomedicine strategies could prolong the use of anthelmintics and control resistance problems.

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