Peritoneal fluid changes in horses subjected to small colon distension

Expression of inflammation-associated genes in circulating leukocytes collected from horses with gastrointestinal tract disease

“…These changes in horses with nonstrangulating GIT obstruction contrast with the results of a study 20 in which circulating neutrophils from horses with this type of GIT disease were not activated. However, the findings of the present study were consistent with the results of another study 33 in which experimentally induced intraluminal colonic obstruction caused damage to the GIT mucosa and induced inflammatory lesions in remote organs. Furthermore, evidence of the activation of circulating leukocytes in horses with naturally occurring nonstrangulating obstruction has been reported.…”

Expression of cyclooxygenase genes in the jejunum of horses during low-flow ischemia and reperfusion

“…Arterial low-flow ischemia contrasts with models in which complete ischemia is produced and is intended to model intestinal disorders (eg, severe intestinal distension and conditions that develop at the periphery of strangulating lesions) in which partial arterial obstruction is thought to develop. [19][20][21][22] We hypothesized that arterial low-flow ischemia would increase COX-2 gene expression in the jejunum of horses and that expression of traditional housekeeping genes would not remain stable under these experimental conditions.…”