Histomorfometria das meninges encefálicas de ratos Wistar em diferentes faixas etárias

Abstract

Pesquisa Veterinária Brasileira 30(11):996-1002. Curso de Ciências Biológicas, Universidade Federal de Goiás, Unidade Jatobá, Setor Parque Industrial, Jataí, GO 75800-000, Brazil. E-mail: kpereira@usp.brThe development of the nervous system is very complex and there are few studies about the organization of the brain envoltories related to the encephalus growing. Using the rat as an animal model, it was proposed to evaluate the several structural aspects of paquimeninge and leptomeninge in different ages. It was used 4 groups of different ages and processed according to the techniques of the light and transmission microscopy. It was verified that the adult rats present a higher area of collagen fibers of type I and III, if compared to the others groups. It was found that, the collagen fibers of type III occupy, in all analyzed groups, a higher area when compared to type I fibers. The results reveal that the Weigert Oxona's staining, which shows elastics, elauninics, and oxitalanics fibers, showed a statistically difference when compared to the Weigert's staining and Verhoeff's staining that show elauninics and elastics fibers, respectively. The ultra-structural aspects demonstrated the presence of many fibroblasts and mitochondria in the paquimeninge and also in the leptomeninges of the neonats and adults groups, indicating the high cellular activity and consequently, an intense formation of conjunctive tissue. As collagen fibers of type III acting on the structural maintenance of delicate and expansive tissues, the study shows that the function of the encephalic meninges are not only related to the to resistance to tractions and tensions that the encephalus is subjected. But also the function related to the distensibility of the meningeos and brain vases according to the sanguineous apport in several specific functions of the nervous system. Aceito para publicação em 24 de agosto de 2010.

Macroscopic aspects of Saimiri sciureus dura mater

“…It consists of three layers: Dura mater (pachymeninge), arachnoid membrane and pia mater, both known as leptomeninge (Pereira et al 2010). In the skull, dura mater demonstrates two layers, endosteal and meningeal.…”

Effects of aging on the architecture of the ileocecal junction in rats

“…Furthermore, elastin was thicker and more fragmented in older people, and there was a greater deposition of calcium in the amorphous material. In a study of aging cerebral meninges, reported decreases and increases in the oxytalan fiber contents of mature elaunin and elastic fibers, respectively [46] . In studies on the vas deferens reinforced these findings, stating that there was an increase in elastin during aging [47] .…”

Efeitos da penicilina G na pelve renal de ratos Wistar (Rattus norvegicus albinus) normais e diabéticos

“…(GARDNER; GRAY; O 'RAHILLY, 1988;DI DIO, 1999;DÂNGELO;FATTINI, 2002;MOORE;DALLEY, 2007). Inclusive, segundo Eagle et al (1947) (GOODMAN et al, 1973;REZENDE, 2000;SPINOSA;GÓRNIAK;BERNARDI, 2006;RANG et al, 2007). O conhecimento das penicilinas em relação ao sistema urinário é grandemente baseado em estudos das taxas de depuração da droga pelo rim.…”

“…O conhecimento das penicilinas em relação ao sistema urinário é grandemente baseado em estudos das taxas de depuração da droga pelo rim. As penicilinas se distribuem por vários tecidos, tendo dificuldade de atravessar a barreira hemato-encefálica, não são biotransformadas no organismo, sendo eliminadas pelos rins, 90% por secreção tubular e 10% por filtração glomerular (GOODMAN et al, 1973;BERGERON, 1975;SPINOSA;GÓRNIAK;BERNARDI, 2006;RANG et al, 2007). Estruturalmente, as fibras elásticas estão constituídas por dois componentes distintos, a elastina e as microfibrilas (SMITH, 1976).…”