Histologia e morfometria em cornos uterinos de cadelas nulíparas, multíparas e tratadas com contraceptivos

Abstract

RESUMO.-Dados histológicos e morfométricos foram obtidos de útero de cadelas nulíparas (n=6), multíparas (n=6) e de cadelas tratadas com contraceptivo (n=6). Para esse fim foram usadas seis amostras de cornos uterinos, em corte médio, para cada grupo. As mensurações das espessuras da parede uterina, endométrio total, miométrio total, miométrio interno, miométrio externo, estrato vascular e diâmetro das glândulas endometriais normais não foram estatisticamente significantes entre as cadelas multí-paras e tratadas, com exceção para a altura do epitélio de glândulas normais. As mensurações das espessuras da parede uterina, endométrio total, miométrio total, miométrio interno, diâmetro das glândulas normais e altura do epité-lio glandular foram significantes, comparando cadelas nulíparas com as multíparas e/ou tratadas, com exceção para as espessuras do miométrio externo e estrato vascular. Diante dos resultados obtidos, pode-se concluir que os dados numéricos confirmam que (1) o uso de anticoncepcionais e sucessivas gestações afetam a estrutura uterina em seu total; (2) (n=6), and bitches treated with contraceptive (n=6). Six samples of uterine horns, cut in average for each group. Measurements of the thickness of the uterine wall, total endometrium, total myometrium, internal myometrium, external myometrium, vascular layer and diameter of normal endometrial glands were not statistically significant between the treated and multiparous bitches, except for the height of the epithelium of normal glands. Measurements of thickness of the uterine wall, total endometrium, total myometrium, myometrium internal diameter and height of the glands of normal glandular epithelium were significant, comparing nulliparous with multiparous bitches and/or treated, except for thickness of the myometrium and vascular outer layer. It can be concluded that (1) the use of contraceptives and successive pregnancies affected uterine structures in its full, (2) the vascular layer and external myometrium were the regions with less variation, (3) morphological changes occurred with the same intensity in the total endometrium and myometrium of treated and multiparous bitches; and (4) the presence of dilated endometrial glands was the difference found in the treated bitches, because they were absent in nulliparous and multiparous ones.INDEX TERMS: Morphometry, uterine horns, endometrium, myometrium, bitches.

Evaluation of cell proliferation and endometrial thickness of bitches in different periods of diestrus

“…In a study by Monteiro et al (2009), it was verified that in nulliparous and multiparous bitches, the endometrial thickness is not statistically different. However, as it is not known whether the metabolic state could interfere with the endometrial thickness of bitches, in this study it was also necessary to analyze the correlation between endometrial thickness and some metabolic indicators.…”

A Saúde Animal E O Uso Do Anticoncepcional

“…Uma única administração desses PGE pode favorecer a ocorrência de hiperplasia ou neoplasia mamária, alterações uterinas, hiperplasia endometrial, atraso no parto, distocia, maceração, malformações, morte fetal e aborto, colocando em risco a vida de fêmeas (ACKERMANN et al, 2014). Além disso, pode ocorrer a masculinização de fêmeas, incontinência urinaria infertilidade, acromegalia, obesidade, disfunções hepáticas, alterações na medula óssea, supressão da glândula adrenal, entre outros (MONTEIRO et al, 2009).…”

The importance of the diestrus stages (early, middle, late) to the diagnosis of the endometrial disease in the bitch

“…Uterine morphometric studies could elucidate endometrial changes related to uterine diseases. Although in canines, there are several studies on morphometry in different tissues, there are few studies on uterine morphometry (Monteiro et al, 2009;Groppetti et al, 2010;Salinas et al, 2017;Gossler et al, 2017), and there are no morphometric studies on END. In this sense, histomorphometric studies on the endometrium could offer exciting data to use as a tool in endometrial diagnosis.…”