Emprego dos marcadores de prognóstico no tratamento para o carcinoma invasor de colo

Abstract

The uterine cervix invasive carcinoma represents a major public health problem, mainly in the developing countries. Its treatment, based on radical hysterectomy, radiotherapy and/or chemotherapy presents a considerable morbidity. Prognostic markers should be taken into consideration in the therapeutic planning, so that the results would be optimized, complications reduced, and patients' survival prolonged. Accepted prognostic markers are: stage, tumoral size, histological type, degree of differentiation, lymphovascular invasion, depth of the stromal invasion, presence of lymph nodal metastases, and surgical margins involvement. This study aims at making a literature review concerning the use of theses markers in the therapeutic planning of women with uterine cervix invasive carcinoma. The treatment based on these markers may present better results, with lower ratio of complications and an improvement in the patients' survival.