2009
DOI: 10.1590/s0100-72032009000300002
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Resistência à insulina em mulheres com síndrome dos ovários policísticos modifica fatores de risco cardiovascular

Abstract: POS and IR women present significant differences in several ultrasonographical, seric and anthropometric markers, which point out to higher cardiovascular risk, as compared to women without POS and IR. In face of that, the systematic IR evaluation in POS women may help to identify patients with cardiovascular risk.

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Cited by 21 publications
(14 citation statements)
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“…(28). A study conducted in North East Brazil (29) on women with and without PCOS, indicated an association between AH and this endocrine disease, revealing a 2-fold prevalence of AH in the group with PCOS (18.6 vs. 9.9, P < 0.05). IR and hyperinsulinemia can explain AH pathogenesis in PCOS: they alter vascular smooth muscular cells causing hypertrophy of vascular smooth muscle with reduced compliance, the interference in the endothelium-dependent vasodilatation mechanism, the activation of the renin-angiotensin-aldosterone system and sodium retention.…”
Section: Pcos and Hypertensionmentioning
confidence: 99%
“…(28). A study conducted in North East Brazil (29) on women with and without PCOS, indicated an association between AH and this endocrine disease, revealing a 2-fold prevalence of AH in the group with PCOS (18.6 vs. 9.9, P < 0.05). IR and hyperinsulinemia can explain AH pathogenesis in PCOS: they alter vascular smooth muscular cells causing hypertrophy of vascular smooth muscle with reduced compliance, the interference in the endothelium-dependent vasodilatation mechanism, the activation of the renin-angiotensin-aldosterone system and sodium retention.…”
Section: Pcos and Hypertensionmentioning
confidence: 99%
“…Dessa forma, a CA representa um importante marcador antropométrico para identificar pacientes com risco de DCV. Na SOP, mulheres que apresentam resistência à insulina possuem circunferência da cintura significativamente maior quando comparadas àquelas sem resistência à insulina 38 .…”
Section: Discussionunclassified
“…A associação entre resistência a insulina (RI) e SOP foi primeiramente relatada em 1980 e estudos posteriores manifestaram que a RI é uma característica da SOP, com uma prevalência estimada entre 64 e 79%, considerando-se amostras de mulheres com SOP de outros países, e entre 44,8 e 70,5%, considerando-se uma amostra da região. Mulheres com SOP apresentam risco elevado para dislipidemia, hipertensão e diabetes mellitus tipo 2, sendo que as mulheres com SOP apresentam uma prevalência até 11 vezes maior de síndrome metabólica (MARTINS et al, 2009).…”
Section: Correlações Da Síndrome Do Ovário Policístico Com a Diabetesunclassified