Avaliação de métodos alternativos à citologia no rastreamento de lesões cervicais: detecção de DNA-HPV e inspeção visual

Gontijo, Rodrigo Modesto Gadelha; Derchain, Sophie Fm; Roteli-Martins, Cecília Maria; Sarian, Luís Otávio; Bragança, Joana Fróes; Zeferino, Luíz Carlos; Silva, Samara Messias da

doi:10.1590/s0100-72032004000400002

Cited by 3 publications

(3 citation statements)

References 8 publications

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“…Most of cervical cancer cases could be prevented by the adherence to cytopathological examination, with a good coverage screening, quality sample collection and correct analysis [3]. According to the World Health Organization (WHO), with at least 80% of the population screened, with confirmed diagnosis and adequate therapy, there could be a reduction from 60 to 90% of cervical cancer cases.…”

Section: Introductionmentioning

confidence: 99%

Quality of Cervical Cancer Screening at a Family Health Unit in Salvador-BA

2021

Journal of Experimental Pathology

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Introduction: Cytopathological examination is the main method for the screening of cervical cancer, its occurrence can be prevented or minimized through screening, with good coverage, quality of collection and analysis and women's adherence to the examination. Objective: To describe the quality of cytopathological exams performed at a family health unit in Salvador -Bahia during the years 2015 and 2016. Method: A cross-sectional study, of an exploratory descriptive character, was conducted, using a database from a previous study carried out in a health unit in Salvador / BA and approved by the Ethical Committee from State University of Feira de Santana. Results: Preventive gynecological exams of 1,350 women were analyzed, but 330 (24.4%) of them could not be evaluated due to the absence of the report in the health unit and the presence of acellular or hypocellular material that prevented the analysis. From 1020 exams, 45 (3.3%) presented an unsatisfactory sample, without conditions for analysis, while 589 (43.19%) showed only squamous cells. From 392 (29.0%) reports with an adequate study sample, 150 (%) were women with a mean age of 38.49 years. These were located and composed the final sample of the present investigation. Final Considerations: We suggest the need for investments in continuing education for professionals involved in performing cytopathological exams, in order to ensure the right of women to comprehensive and quality health care.

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Section: Introductionmentioning

confidence: 99%

Quality of Cervical Cancer Screening at a Family Health Unit in Salvador-BA

2021

Journal of Experimental Pathology

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“…(5,7,8) O exame citopatológico é o principal método para o diagnóstico precoce das lesões cervicais pré-neoplásicas. (9) Segundo as Diretrizes Brasileiras para o rastreamento do câncer de colo uterino, (3) o rastreio por meio do exame citopatológico deve ser realizado em mulheres a partir dos 25 até 64 anos de idade. Os dois primeiros exames devem ser realizados anualmente e, após dois resultados negativos, os próximos devem ser realizados a cada 3 anos.…”

Section: Introductionunclassified

“…(12,13) Para acompanhamento de mulheres com diagnóstico de ASC, vêm sendo utilizados testes de biologia molecular para detecção do DNA-HPV através dos métodos de captura híbrida e reação em cadeia da polimerase (PCR) vinculados ao exame citopatológico; contudo, no Brasil, a conduta preconizada é a repetição da citologia e realização de colposcopia e biópsia. (9,14) Estudos mostram que cerca de 55% de mulheres com ASC apresentam resultados positivos para HPV, e cerca de 10% a 20% das mulheres com HPV positivo tinham lesão pré-câncer ou câncer. (15) O objetivo do estudo consiste em verificar a prevalência de resultados positivos para ASC na população atendida em um laboratório de Caxias do Sul.…”

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Prevalence of atypias of indetermined meaning and its relationship with papilomavirus in a population of Caxias do Sul

Feijó¹,

Cavagnolli²

2018

Revista Brasileira De Análises Clínicas

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Artigo Original/Original Article Resumo Objetivo: Analisar a prevalência dos resultados positivos para Células Escamosas Atípicas (ASC) em uma população da rede privada em Caxias do Sul e sua associação com o HPV. Métodos: Foram analisados resultados de exames citopatológicos do colo uterino no período de 2015 a 2017. Para presença de HPV foram avaliados os resultados histopatológicos da biópsia e de biologia molecular por reação em cadeia polimerase (PCR). Resultados: A prevalência de ASC foi de 2,48%, sendo que 58% das pacientes realizaram seguimento. A histopatologia mostrou prevalência de HPV, associado às lesões cervicais em 46,4% e 59,4% para ASC-US e ASC-H respectivamente. A prevalência de HPV no teste de PCR foi de 30,4%, sendo os subtipos mais prevalentes o HPV16 e 18. Conclusão: O percentual de exames de ASC em uma população de Caxias do Sul mostrou-se dentro dos valores adequados. Na histopatologia houve uma maior associação de ASC-H com lesões de alto grau e presença de HPV. Isso mostra a necessidade e a importância do seguimento das pacientes com resultados de ASC, principalmente para ASC-H. Palavras-chave Colo do útero; Neoplasias do colo do útero; Células escamosas atípicas

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Quality of Cervical Cancer Screening at a Family Health Unit in Salvador-BA

Coelho

Silva

Santos

et al. 2021

Preprint

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Introduction: Cytopathological examination is the main method for the screening of cervical cancer, its occurrence can be prevented or minimized through screening, with good coverage, quality of collection and analysis and women's adherence to the examination. Objective: To describe the quality of cytopathological exams performed at a family health unit in Salvador - Bahia during the years 2015 and 2016. Method: A cross-sectional study, of an exploratory descriptive character, was conducted, using a database from a previous study carried out in a health unit in Salvador / BA and approved by the Ethical Committee from State University of Feira de Santana. Results: Preventive gynecological exams of 1,350 women were analyzed, but 330 (24.4%) of them could not be evaluated due to the absence of the report in the health unit and the presence of acellular or hypocellular material that prevented the analysis. From 1020 exams, 45 (3.3%) presented an unsatisfactory sample, without conditions for analysis, while 589 (43.19%) showed only squamous cells. From 392 (29.0%) reports with an adequate study sample, 150 (%) were women with a mean age of 38.49 years. These were located and composed the final sample of the present investigation. Final Considerations: We suggest the need for investments in continuing education for professionals involved in performing cytopathological exams, in order to ensure the right of women to comprehensive and quality health care.

show abstract

Avaliação de métodos alternativos à citologia no rastreamento de lesões cervicais: detecção de DNA-HPV e inspeção visual

Cited by 3 publications

References 8 publications

Quality of Cervical Cancer Screening at a Family Health Unit in Salvador-BA

Quality of Cervical Cancer Screening at a Family Health Unit in Salvador-BA

Prevalence of atypias of indetermined meaning and its relationship with papilomavirus in a population of Caxias do Sul

Quality of Cervical Cancer Screening at a Family Health Unit in Salvador-BA

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