Síndrome de Stewart Treves: relato de caso

Silva, Elisvania Rodrigues da; Cavalcante, Emmanuel Filizola; Ferreira, Francisco Valdeci de Almeida; Soares, Lázaro Rogério Carvalho; Juaçaba, Sérgio Ferreira; Ximenes, Rogério Aguiar

doi:10.1590/s0100-72032003000300011

Cited by 4 publications

(5 citation statements)

References 7 publications

(14 reference statements)

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“…Five-year survival rates are between 10% and 35%. 2 , 3 , 4 , 5 In conclusion, the authors reported a case of STS in the lower limb. We must maintain a high index of suspicion in skin lesions in chronically swollen member, even those of benign appearance, because early treatment can improve the potential for patient survival.…”

Section: Discussionmentioning

confidence: 70%

“…1 , 3 The disease demonstrates positivity for endothelial cell markers such as factor VIII and anti-CD34 and anti-CD31 antibodies, the latter being the one with greater sensitivity and specificity. 2 , 4 , 5 The infrequent occurrence of this disease and the innocuous appearance of the tumor lead to delays in diagnosis and treatment. 3 …”

Section: Discussionmentioning

confidence: 99%

“… 2 , 3 Early recognition of suspicious lesions in a lymphomatous limb and biopsy are essential, due to the poor prognosis of this entity, with a high rate of local recurrence, systemic dissemination and poor survival rate in five years. 1 , 4 …”

Section: Introductionmentioning

confidence: 99%

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Stewart-Treves Syndrome of the Lower Extremity

Veiga

Nascimento

Carvalho

et al. 2015

An. Bras. Dermatol.

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Stewart-Treves syndrome is a rare cutaneous angiosarcoma that develops in long-standing chronic lymphedema. Though most commonly this angiosarcoma is a result of post mastectomy lymphoedema, it also develops in Milroy disease, idiopathic, congenital, traumatic and filarial lymphoedema. Despite the rarity of this syndrome and its poor prognosis, early diagnosis associated with radical surgery can provide improved survival. We report a case of angiosarcoma in the lower limb in a patient with chronic lymphedema associated with history of repeated erysipela episodes.

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Section: Discussionmentioning

confidence: 70%

Section: Discussionmentioning

confidence: 99%

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Stewart-Treves Syndrome of the Lower Extremity

Veiga

Nascimento

Carvalho

et al. 2015

An. Bras. Dermatol.

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“…O diagnóstico é baseado na histopatologia que tem como principais achados os espaços vasculares irregulares com tamanhos variados, revestidos por células poligonais, com núcleos hipercromáticos e pleomórficos e células tumorais redondas a ovoides 1,10 . Como são neoplasias pouco diferenciadas, frequentemente necessitam complementação diagnóstica com imuno-histoquímica que apresenta positividade para marcadores de células endoteliais, tais como fator VIII, vimentina, FLI-1, CD34 e CD31 1,3,11 . A SST apresenta um prognóstico ruim e está sujeita a metástases à distância e recorrência local 9 .…”

Section: Discussionunclassified

“…Quimioterapia e radioterapia podem ser opções para casos inoperáveis ou que recusem a cirurgia. Considerando os resultados decepcionantes da terapia atual, medidas como o seguimento regular de pacientes com linfedema de longa duração, pacientes pós mastectomia radical e ressecção radical para câncer de colo de útero, devem ser encorajadas para prevenir o atraso no diagnóstico 9,11 . Apesar de a SST ser uma condição rara, é essencial que seu diagnóstico seja realizado precocemente devido à sua alta morbidade e mortalidade.…”

Section: Discussionunclassified

Síndrome de Stewart-Treves no membro inferior com apresentação exuberante: Relato de caso

Krapf

Welter

Reginatto

et al. 2023

CBR

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A Síndrome de Stewart-Treves é uma rara condição onde um angiossarcoma se desenvolve sobre área de linfedema crônico. Afeta mais frequentemente os membros superiores e representa 5% dos casos de angiossarcoma. Apesar de ser mais comum em mulheres submetidas a mastectomia radical e esvaziamento axilar por neoplasia de mama, pode ocorrer a partir de linfedema de outras etiologias. Clinicamente as lesões são caracterizadas por nódulos únicos ou múltiplos de cor avermelhada ou azulada no estágio inicial e, em estágio avançado, podem evoluir para massas hemorrágicas e até gangrena. O prognóstico é ruim e a conduta cirúrgica com excisão ampla ou amputação oferecem uma maior chance de sobrevida. Relata-se um caso de Síndrome de Stewart-Treves na perna direita, apresentando-se de forma exuberante e com acometimento de linfonodos pélvicos e abdominais.

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Unsuspected Stewart–Treves syndrome clinically mimicked by apparent bullous erysipelas and a systematic review of dermatological presentations of the classical Stewart–Treves syndrome

et al. 2018

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Background Stewart Treves–Syndrome (STS) was first characterized as angiosarcoma in the homolateral limb of a patient with breast cancer and lymphedema. Now, other conditions represent STS. It's a rare condition. The diagnosis is easier in the presence of single or multiple purple nodules. Even though other dermatological aspects have been reported, no study has grouped its characteristics. Aim Evaluate the dermatological characteristics of classical STS (c‐STS). Methods and Results We report a patient with chronic lymphedema with a history of recurrent erysipelas that rapidly developed multiple papules in the superior limb. It was initially diagnosed as bullous erysipelas, but unsatisfactory evolution led to biopsy, which demonstrated an unsuspected epithelioid angiosarcoma. We have also performed a review of dermatologic aspects of c‐STS using PubMed and Lilacs databases. PICTOS methodology and PRISMA flow chart were considered. The main dermatological aspects associated with c‐CTS were summarized. Using a systematic evaluation from 109 articles, 29 were selected and 44 patients were described to whom we added one case. The mean time with lymphedema was 10 years. Of the patients analyzed, 97.2% were female; 95.6% were submitted to radical mastectomy; 81.2% presented with multiple lesions, 67.4% of the lesions were reported as nodules or tumors, 53.4% were purple, 33.4% were associated with an ecchymotic halo, and 33.4% were ulcerated lesions. Conclusion When evaluating patients with chronic lymphedema with new dermatological abnormalities, clinical suspicion, or unfavorable evolution, the knowledge of clinical signs is important for diagnosis, and a biopsy must be considered. Papules associated with erythematous‐wine color and bluish hematoma aspect must raise clinical suspicion.

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Síndrome de Stewart Treves: relato de caso

Cited by 4 publications

References 7 publications

Stewart-Treves Syndrome of the Lower Extremity

Stewart-Treves Syndrome of the Lower Extremity

Síndrome de Stewart-Treves no membro inferior com apresentação exuberante: Relato de caso

Unsuspected Stewart–Treves syndrome clinically mimicked by apparent bullous erysipelas and a systematic review of dermatological presentations of the classical Stewart–Treves syndrome

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