Adenocarcinoma gástrico Borrmann tipo IV: análise dos resultados da ressecção curativa

Abstract

Results Results Results Results: Of the 123 patients studied, 68 underwent gastrectomy, 52 (42.3%) with curative intent and 16 (13%) palliative resection, while 55 (44.7%) had disease not subject to resection. Three postoperative deaths followed the curative resection, constituting a mortality rate of 5.76%. In nine (17.3%) patients there were technical complications, and esophagojejunal fistula seven cases, the most frequent. All technical complications and deaths occurred after total gastrectomy, which was the most commonly performed curative resection type in this series. The most common pattern of recurrence was peritoneal carcinomatosis. The location of the tumor, lymph node metastasis, lymphatic invasion and pathological staging were considered significant prognostic factors. The median survival time was 29 months, with a rate of five-year survival of 33% in patients undergoing curative resection. Conclusion Conclusion Conclusion Conclusion Conclusion: The curative resection of B IV gastric adenocarcinoma had a positive impact on survival of patients with the disease in stages IB, II and III, with up to 15 lymph nodes (pN2) and localized type.

Clinicopathologic characteristics and prognosis of Borrmann type IV gastric cancer: a meta-analysis

“…5a ). Six studies reported median survival times for B-4 patients after non-curative resection or non-resection [ 13 , 14 , 20 – 23 ]. In these studies, 434 patients underwent non-curative resection and 304 patients underwent non-resections, such as an exploratory laparotomy.…”

“…At present, most physicians do not recommend LUAE + Apl because it is not effective for patients with stage IV gastric cancer and may cause severe post-operative complications. Besides, some researchers believe that extended lymphadenectomy should be performed if patient’s clinical condition allowed, because it may allow a better assessment of nodal stations and decrease the chance of stage worsening [ 20 ].…”

Correlations between vascular invasion, neural structures invasion and microvessel density with clinicopathological parameters in gastric cancer

“…Gastric carcinoma is a fairly prevalent malignancy worldwide, representing the second leading cause of death secondary to cancers [1]. Despite recent medical advances, the outcome secondary to gastric cancer remains discouragingly and the survival rate of advanced disease stages is decreased.…”