Efeito da suplementação oral de vitamina C na resistência anastomótica intestinal

“…18 It participates in the integrity of connective tissue, cartilage, osseous matrix, tendons, and skin, besides being involved in the cicatricial process. 18 , 19 It also has an anti-inflammatory effect and important antioxidant action, preventing formation of free radicals. 18 – 20 …”

Section: Introductionmentioning

confidence: 99%

Assessment of clinical effects and safety of an oral supplement based on marine protein, vitamin C, grape seed extract, zinc, and tomato extract in the improvement of visible signs of skin aging in men

Costa¹,

Pereira²,

Assumpção³

et al. 2015

CCID

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BackgroundSkin aging is a natural process that may be aggravated by environmental factors. Topical products are the conventional means to combat aging; however, the use of oral supplements is on the rise to assist in the management of aged skin.ObjectiveThe purpose of this study was to assess the effects and safety of an oral supplement containing (per tablet) marine protein (105 mg), vitamin C (27 mg), grape seed extract (13.75 mg), zinc (2 mg), and tomato extract (14.38 mg) in the improvement of skin aging in men.MethodsThis single-center, open-label, quasi-experimental clinical study enrolled 47 male subjects, aged 30–45 years, with phototypes I–IV on the Fitzpatrick scale. Subjects received two tablets of the oral supplement for 180 consecutive days. Each subject served as their own control. Clinical assessments were made by medical personnel and by the subjects, respectively. Objective assessments were carried out through pH measurements, sebumetry, corneometry, ultrasound scanning, skin biopsies, and photographic images.ResultsForty-one subjects (87%) completed the study. Clinical improvements on both investigator- and subject-rated outcomes were found for the following parameters: erythema, hydration, radiance, and overall appearance (P<0.05). The objective measurements in the facial skin showed significant improvements from baseline in skin hydration (P<0.05), dermal ultrasound density (P<0.001), and reduction of skin pH (P<0.05). No statistical improvement in relation to sebum was found. The photographic assessment showed an improvement in the overall appearance. The results of the objective measurements were found to be correlated with the subjects’ satisfaction by an increase of collagen and elastic fibers.ConclusionThe use of an oral supplement based on a unique biomarine complex, vitamin C, grape seed extract, zinc, and tomato extract produced improvements in the signs of skin aging in men.

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Can specific nutrients stimulate bowel wound healing?

Ellinger

2016

Current Opinion in Clinical Nutrition &Amp; Metabolic Care

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Efeito da suplementação oral de vitamina C na resistência anastomótica intestinal

Abstract: Vitamin C increased the resistance of jejunal anastomoses in rats, both in the immediate and in late postoperative periods. In addition, the final resistance of intact jejunal segments of rats under administration of vitamin C was significantly higher than in the control group.

Cited by 7 publications

References 15 publications

Incidência da deficiência de vitamina B12 em pacientes submetidos à cirurgia bariátrica pela técnica Fobi-Capella (Y-de-Roux)

Incidência da deficiência de vitamina B12 em pacientes submetidos à cirurgia bariátrica pela técnica Fobi-Capella (Y-de-Roux)

Assessment of clinical effects and safety of an oral supplement based on marine protein, vitamin C, grape seed extract, zinc, and tomato extract in the improvement of visible signs of skin aging in men

Can specific nutrients stimulate bowel wound healing?

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