O etil-2-cianoacrilato como selante após ressecção parcial de ceco em rattus norvegicus albinus

Faion, Adilson Gomes; Filho, Augusto Diogo; Alcântara, Tânia Machado de; Ferreira, Taciana Fernandes Araújo

doi:10.1590/s0100-69912011000100009

Cited by 9 publications

(7 citation statements)

References 12 publications

(23 reference statements)

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“…compounds have been used as complement to conventional sutures. There are studies that show that they are able to create syntheses with no suture in intestines since they do not cause tissue ischemia 6,7 .…”

Section: IImentioning

confidence: 99%

The aplication of cyanoacrilate surgical glue on skin suture in rats

Neto¹,

Aydos²,

Silva³

et al. 2017

Acta Cir. Bras.

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Purpose: To compare the use of a new cyanoacrylate-based surgical glue and suture with separate points in skin wounds closure. Methods: Thirty-six rats were subjected to a 4cm dorsal longitudinal incision. Twelve were subjected to simple suture with polyamide 6-0, 12 rats underwent wall synthesis using Dermabond® and 12 was performed cutaneous synthesis with N-2-Butyl-Cyanoacrylate. Twelve of each group was euthanized on the seventh postoperative day, their blood was taken to biochemical tests and a layer of skin and subcutaneous tissue surrounding the surgical scar was randomly divided in two segments, to the submission of tension tests and to histological study. Results: There were no significant difference between groups (p>0.05). In the soft dermis there was more type I collagen production in group I (p<0.05), group II and III was similar re-sults (p>0.05). In the compact dermis, all 3 groups showed similar results (p>0.05). The biomechanical study was similarity between the glue groups (p>0.05) but the group III proved to be different from the others having a higher resistance (p>0.05). Conclusion: This glue does not cause any inflammation or kidney and hepatic toxicity. Polyamide sutures are more resistant and the glue should be used alone only in less tension are-as.

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Section: IImentioning

confidence: 99%

The aplication of cyanoacrilate surgical glue on skin suture in rats

Neto¹,

Aydos²,

Silva³

et al. 2017

Acta Cir. Bras.

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“…These adhesives have advantages over conventional sutures for the skin and mucous membranes and are indicated for a variety of syntheses such as gingival lesions, skin and mucosa lacerations, with excellent biocompatibility and few secondary tissue reactions. compatible with injuries on the back of rats as used in this research, with higher tension 6 .…”

Section: Discussionmentioning

confidence: 80%

“…Usually, these compounds have been used as complements to conventional sutures, being their use isolated and, when used, presenting questionable results 6 .…”

Section: Introductionmentioning

confidence: 99%

Use of cyanoacrylate-based surgical adhesives associated to the macroporous tape in skin synthesis in rats

Neto

Aydos²,

Silva³

et al. 2019

Acta Cir. Bras.

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Purpose:To compare the use of new cyanoacrylate surgical adhesive associated with macroporous tapes in cutaneous synthesis.Methods:Male Wistar rats with a longitudinal incision of 4cm were used on the back, divided into four groups: GI used octyl-cyanoacrylate (Dermabond®), GII used N-2-butylcyanoacrylate, GIII used octyl-cyanoacrylate and macroporous tape and GIV used N-2-butyl cyanoacrylate and macroporous tape. On the fourteenth day, the rats were submitted to euthanasia, were divided in two parts, and a layer of skin subcutaneous tissue through an area of operative healing was removed. One part was submitted to the study of rupture strength with the use of tensiometer, and in the other part histological examination was performed.Results:No force test was similar between groups I and II, being different from groups III and IV (P <0.001), which were identical to each other (P> 0.05). The units were compared among the studied groups, and they were different with the use of macroporous tapes (P> 0.05).Conclusions:The purpose of macroporous tapes is associated with CA adhesives in cutaneous tissues that provide more resistant scars. The use of a combination of macroporous tapes leads to complete re-epithelialization, without provoking foreign body reaction, has hemostatic properties and does not cause an absorptive reaction.

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“…Furthermore, there have been experimental studies that have shown the advantages of suture-free intestinal application using tissue adhesive, because tissue adhesives do not impair the tissue perfusion (Weiss and Haj 2001 ; Kanellos et al 2002 ; Faion et al 2011 ). However, there have so far been no reports of cyanoacrylate tissue adhesive use for stoma creation.…”

Section: Introductionmentioning

confidence: 99%

A sutureless technique using cyanoacrylate adhesives when creating a stoma for extremely low birth weight infants

et al. 2016

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PurposeIntestinal perforation and necrotizing enterocolitis (NEC) are neonatal intestinal emergencies that are especially common in premature infants. While prompt surgical intervention, including stoma creation, is often required, the optimal surgical treatment has been controversial because of the substantial risks related to the stoma creation and management. The use of a tissue adhesive may have some advantages over the use of sutures when creating an intestinal stoma in extremely low birth weight (ELBW) infants. The purpose of this report was to present a novel approach for creating a stoma using a tissue adhesive in ELBW infants.MethodsA total of eight ELBW infants that underwent laparotomy with the creation of intestinal stomas using cyanoacrylate adhesive at our institution between 2009 and 2014 were enrolled. The clinical parameters, including the length of the operation, intra- and postoperative complications and the outcomes were evaluated.ResultsThe median body weight and gestational age at birth were 630 g and 24.3 weeks, respectively. The median age at referral was 11.5 days. The median length of the procedure was 58.5 min, including the inspection and resection of the intestine. All procedures were completed without any intraoperative complications. There were no postoperative complications associated with the stoma. Two patients died of the associated septic status.ConclusionsSutureless enterostomy using cyanoacrylate adhesive is a simple technique which has the potential to reduce the incidence of complications related to the intestinal stoma in ELBW infants.

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O etil-2-cianoacrilato como selante após ressecção parcial de ceco em rattus norvegicus albinus

Cited by 9 publications

References 12 publications

The aplication of cyanoacrilate surgical glue on skin suture in rats

The aplication of cyanoacrilate surgical glue on skin suture in rats

Use of cyanoacrylate-based surgical adhesives associated to the macroporous tape in skin synthesis in rats

A sutureless technique using cyanoacrylate adhesives when creating a stoma for extremely low birth weight infants

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