Câncer anal e doenças sexualmente transmissíveis: qual a correlação?

Abstract

There was a high positive correlation between anal cancer and HPV admissions in Brazil. There were negative correlations between anal cancer and Gonococci infection and between anal cancer and Chlamydia infection admissions.

The human papillomavirus (HPV)-related cancer biology: An overview

“…Although the anal cancer is considered a rare, representing 3% of all gastrointestinal tract neoplasms, the disease incidence has grown 2% per year since 1970, being related to sexual behavior, being closely related to HIV-infected patients [140,[270][271][272]. In Brazil, for example, it was verified an increase in 116% of anal cancer incidence among 1998 and 2007 [271]. The disease is most frequent in women and homosexual men, that are 15 fold most susceptible to the HPV-associated anal carcinoma [273,274].…”

Métodos combinados para avaliação e diagnóstico do câncer anal induzido por Papilomavírus Humano (HPV): revisão bibliográfica

“…Mas há uma correlação positiva elevada entre as internações por câncer anal e HPV. Estudos amostrais corroboram a informação ao registrarem aumento da neoplasia, com possível tendência de mortalidade no país 9 .…”

Association Among Histological Findings Suggestive of Papilloma Virus on Hemorrhoidectomy Specimens

“…About 45 subtypes infect the epithelium of the male and female anogenital tract. Among these, 13 and 18 are considered of high oncogenic risk, mainly the 16 and 18 types, associated to the anogenital cancer and of the aerodigestive tract 2 , 3 , 8 , 10 .…”

“…The anal HPV predominates in some groups, such as in patients carrying idiopathic anal itching, with antecedents of clinical form of anal HPV treatment, with antecedents of genital HPV treatment, who look for the ambulatories of sexually transmitted diseases, HIV positives, prostitutes and with risky behavior for sexually transmitted diseases. However, this disease also affects people who do not belong to these groups, and may be acquired by other forms beyond the sexual relationship 2 , 6 , 7 , 8 , 10 .…”

“…The anal infection by HPV was now established as a risk factor for precursor anal injuries and anal cancer. Only a few investigators examined the prevalence and incidence of this anal infection, and the studies have been limited to the populations infected by HIV and immune depressed 2 , 8 , 9 , 11 .…”