Synthesis, structure and physicochemical properties of zinc and copper complexes based on sulfonamides containing 8-aminoquinoline ligands

Abstract

Recebido em 10/8/07; aceito em 14/11/07; publicado na web em 8/7/08 Sulfonamides obtained by reaction of 8-aminoquinoline with 4-nitrobenzenesulfonylchloride and 2,4,6-triisopropylbenzenesulfonyl chloride were used to synthesize coordination compounds with Cu II and Zn II with a ML 2 composition. Determination of the crystal structures of the resulting zinc and copper complexes by X-ray diffraction show a distorted tetrahedral environment for the [Cu(qnbsa) 2 ], [Cu(qibsa) 2 ] and [Zn(qibsa) 2 ] complexes in which the sulfonamide group acts as a bidentate ligand through the nitrogen atoms from the sulfonamidate and quinoline groups. The complex [Zn(qnbsa) 2 ] crystallizes with a water molecule from the solvent and the Zn is five-coordinated and shows a bipyramidal-trigonal geometry. The electrochemical and electronic spectroscopy properties of the copper complexes are also discussed.

Synthesis and Characterization of Half‐Sandwich Ruthenium Complexes Containing Aromatic Sulfonamides Bearing Pyr­id­inyl Rings: Catalysts for Transfer Hydrogenation of Acetophenone Derivatives

“…[9][10][11] Sulfonamides containing 8-aminoquinoline have rarely been studied by the scientific community, and mostly only in relation to their luminescent properties. [12][13][14][15][16] Also, catalysis and the molecular structural properties of sulfonamides have recently been studied in detail by our research team. [17a-17d] Ketone TH catalyzed by Ru II complexes containing Ndonor ligands has attracted increasing attention [18][19][20][21][22][23][24][25][26][27][28][29][30][31][32] since the success of Noyori's work using 1,2-diamine ligands.…”

Preparation, Characterization, and Antimicrobial Activities of Bimetallic Complexes of Sarcosine with Zn(II) and Sn(IV)

“…The medical applications of Zn(II) compounds include treatments of parasitic diseases (eczema, ringworm, fungus, and athletes foot), and in many biological processes zinc plays an important role as metalloenzymes in which Zn(II) is coordinated by a ligand that leads to a structural as well as functional model [10]. …”

Dmap-Catalyzed Synthesis of Novel Pyrrolo[2,3-D]Pyrimidine Derivatives Bearing an Aromatic Sulfonamide Moiety

“…22,23 A perusal of the literature revealed that sulfonylation of amines with sulfonyl chlorides is commonly performed in pyridine as the base and medium. [24][25][26][27][28] 4-(N,N-Dimethylamino)pyridine (DMAP) is a very good nucleophilic catalyst and is more basic than pyridine. DMAP is widely used as a superb nucleophilic catalyst for many organic reactions such as Baylis-Hillman reaction, 29,30 regioselective acylation of 6-O-protected octyl β-D-glucopyranosides, 31 synthesis of electrophilic alkenes, 32 heroin synthesis, 33 and synthesis of N-sulfonyl monocyclic β-lactams.…”