Montmorillonite clays are of great interest for industrial processes such as catalysis and adsorption. The textural properties of clays can be modified in an attempt to increase their uses. This paper describes the acid treatment of natural montmorillonite clay. The materials were characterized using X-ray diffraction (XRD), atomic absorption spectroscopy (AA) and BET surface area measurements. Three different acids (HCl, HNO 3 and H 2 SO 4 ) were tested, and HCl and H 2 SO 4 were more efficient for removing Fe from the clay. The results indicate that HCl better preserves the material structure because less Al is removed. A central composite design (CCD) 2 2 was applied to evaluate the treatment using /75 °C, assured that Fe was removed with less damage to the structure.