Local behavior and lymph node metastases of Wilms' tumor: accuracy of computed tomography

Silva, Eduardo Just da Costa e; Silva, Giselia Alves Pontes da

doi:10.1590/s0100-39842014000100007

Cited by 3 publications

(2 citation statements)

References 23 publications

(40 reference statements)

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“…Knowledge of the location and characteristics of the lymph nodes of the head and neck is essential for the recognition of diseases such as tuberculosis, sarcoidosis, histoplasmosis, Hodgkin lymphoma, extrathyroid tumor metastases (to the lung, breast, esophagus, larynx, or other sites), and differentiated thyroid cancer ( 1 ) . The use of imaging methods to evaluate the characteristics of those lymph nodes assists the physician in the diagnostic process ( 2 ) , given that the clinical examination alone is often insufficient for a proper evaluation.…”

Section: Introductionmentioning

confidence: 99%

Ultrasound evaluation of the morphometric patterns of lymph nodes of the head and neck in young and middle-aged individuals

et al. 2016

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ObjectiveTo show the morphometric patterns of lymph nodes of the head and neck, evaluating their number, shape, dimensions, hilum, and cortex, through the use of ultrasound examination of the neck.Materials and MethodsWe analyzed 400 right and left lymph nodes in a group of 20 healthy young and middle-aged individuals of both genders.ResultsIn the ultrasound examination, we observed the following lymph nodes: mastoid; parotid (superficial, extraglandular, and intraglandular); submandibular (preglandular, retroglandular, and intracapsular); submental; and cervical (anterior and posterior). Although some individuals had up to seven lymph nodes in the same region, most had only two to three per region. The smallest lymph node diameter observed was 0.4 cm, and the largest was 2.7 cm. Most lymph nodes showed an elongated or oval shape. Most of the lymph node hila were echogenic, although a few were hyperechoic. However, the cortex was clearly hypoechoic in all of the lymph nodes evaluated.ConclusionUltrasound examination of healthy individuals allowed the characteristics of the lymph nodes of the head and neck to be observed clearly, which could provide a basis for the analysis of patients with diseases of these lymph nodes.

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Section: Introductionmentioning

confidence: 99%

Ultrasound evaluation of the morphometric patterns of lymph nodes of the head and neck in young and middle-aged individuals

et al. 2016

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“…Imaging is also useful for ruling out disease in extracapsular structures; for example, in our study, NPV for ureteric involvement was 91 to 93% and that for retroperitoneal adenopathy was 93 to 97%. In another retrospective review of 26 CT scans by Silva et al, 9 CT tumor showed low specificity and low PPV in the detection of lymph node dissemination; however, the reported NPV was 100%.…”

Section: Discussionmentioning

confidence: 95%

Retrospective Study of Diagnostic Accuracy of Computed Tomography-Based Staging of Wilms’ Tumor in the Era of Multidetector Computed Tomography

Pathak

Kembhavi

Popat

et al. 2019

Journal of Gastrointestinal and Abdominal Radiology

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Objectives To evaluate the diagnostic accuracy of multidetector computed tomography (MDCT)–based staging of Wilms’ tumor (WT) in comparison with surgical-pathological staging (reference standard) and to assess the interobserver agreement in predicting CT stage for WT. Method Retrospective audit of 50 consecutive cases of WT meeting our eligibility criteria was performed, and an electronic database of CT scan findings, intraoperative findings, and final histopathology staging were created. Two radiologists blinded to surgical and histologic findings reviewed the CT scans, using multiplanar reformations to assess various parameters pertaining to tumor extent and assign a possible stage, which was then compared with the final surgical-pathological stage. Interobserver agreement was assessed using κ-coefficient. Results CT scan correctly staged 31 (62%) of 50 WT cases (both observers’ consensus data, all stages combined). CT accuracy was 37.5% in stage I disease, 66% in stage II disease, and 75% in stage III. There was substantial interobserver agreement (in 80% of the cases) in assigning the stage. Subset analysis showed a 100% positive predictive value (PPV) in detecting renal vein thrombosis. The negative predictive value (NPV) for ureteric involvement was 91 to 93%, and that for retroperitoneal adenopathy, it was 93 to 97%. Conclusion The accuracy of CT in staging WT is dependent on the disease stage. While it overestimates the extent of the disease in early stage, it predicts the advanced stage with very good accuracy and can be used to avoid upfront surgeries in locally advanced WT.

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Teratoma: a set of teeth in the pelvis

et al. 2015

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Local behavior and lymph node metastases of Wilms' tumor: accuracy of computed tomography

Cited by 3 publications

References 23 publications

Ultrasound evaluation of the morphometric patterns of lymph nodes of the head and neck in young and middle-aged individuals

Ultrasound evaluation of the morphometric patterns of lymph nodes of the head and neck in young and middle-aged individuals

Retrospective Study of Diagnostic Accuracy of Computed Tomography-Based Staging of Wilms’ Tumor in the Era of Multidetector Computed Tomography

Teratoma: a set of teeth in the pelvis

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