Tumor miofibroblástico inflamatório da bexiga em criança: relato de caso

Filho, José de Arimatéia Batista Araújo; Martines, João Augusto dos Santos; Martines, Brenda Margatho Ramos; Cavalcanti, Marcella Santos; Cerri, Giovanni Guido; Castro, Cláudio Campi de

doi:10.1590/s0100-39842012000400010

Cited by 1 publication

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“…An IMT is usually found in children and young adults, slightly more often in female (F:M = 4:3) and localized mainly in the lungs, however it may arise in almost every location. IMTs situated in the bladder are very rare [2,5-12]. To our knowledge, the presented case is the first IMT coexisting with the other neoplasm.…”

Section: Discussionmentioning

confidence: 99%

Inflammatory myofibroblastic tumor of the bladder – an unexpected case coexisting with an ovarian teratoma

et al. 2014

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Inflammatory myofibroblastic tumors (IMTs) mainly occur in children and young adults, usually in the first two decades of life. IMT-type tumors belong to neoplasms of an intermediate biologic potential with considerable rate of local recurrence and in some cases that able to create metastases. Presented case is the first IMT coexisting with the other neoplasm. In our paper we are going to present a peculiar case of an IMT of the bladder coexisting with an ovarian teratoma, and to discuss its pathogenesis, histological picture and differential diagnosis. A 19-year-old female was admitted to the Gynecological Department and during the surgery, two independent, non-adjacent tumors were found. To settle the diagnosis, a FISH examination with the ALK1 break apart probe was carried out. It confirmed the rearrangement of the chromosome 2p23. Morphologic and immunophenotypic similarities between an IMT and other malignant tumors of the bladder may lead to diagnostic errors and an unnecessary radical cystectomy as a result. The therapy of choice is only total excision of the tumor.Virtual SlidesThe virtual slide(s) for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/1937487606122622

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Section: Discussionmentioning

confidence: 99%