Qual o seu diagnóstico?

Nacif, Marcelo Souto; Noureldin, Radwa; Sibley, Christopher T.; Türkbey, Evrim; Lima, João A.C.; Bluemke, David A.

doi:10.1590/s0100-39842010000500004

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Non Invasive Cardiac Imaging1

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Cited by 2 publications

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“…The T1 time is shortened by the presence of fi-brosis, and T1 mapping is a powerful tool for quantifying the extent and aggressiveness of such abnormality. The T1 mapping technique has already been validated by means of myocardial biopsies in the clinical context of patients with nonischemic fibrosis who were referred for cardiac transplant (16) . Myocardial extracellular volume measurements quantify diffuse fibrosis not readily detectable by conventional late gadolinium enhancement (13,14) .…”

Section: Non Invasive Cardiac Imagingmentioning

confidence: 99%

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et al. 2011

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Section: Non Invasive Cardiac Imagingmentioning

confidence: 99%

[No Title Available]

et al. 2011

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Interstitial Myocardial Fibrosis Assessed as Extracellular Volume Fraction with Low-Radiation-Dose Cardiac CT

et al. 2012

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Purpose:To develop a cardiac computed tomographic (CT) method with which to determine extracellular volume (ECV) fraction, with cardiac magnetic resonance (MR) imaging as the reference standard. Materials and Methods:Study participants provided written informed consent to participate in this institutional review board-approved study. ECV was measured in healthy subjects and patients with heart failure by using cardiac CT and cardiac MR imaging. Paired Student t test, linear regression analysis, and Pearson correlation analysis were used to determine the relationship between cardiac CT and MR imaging ECV values and clinical parameters. Results:Twenty-four subjects were studied. There was good correlation between myocardial ECV measured at cardiac MR imaging and that measured at cardiac CT (r = 0.82, P , .001). As expected, ECV was higher in patients with heart failure than in healthy control subjects for both cardiac CT and cardiac MR imaging (P = .03, respectively). For both cardiac MR imaging and cardiac CT, ECV was positively associated with end diastolic and end systolic volume and inversely related to ejection fraction (P , .05 for all). Mean radiation dose was 1.98 mSv 6 0.16 (standard deviation) for each cardiac CT acquisition. Conclusion:ECV at cardiac CT and that at cardiac MR imaging showed good correlation, suggesting the potential for myocardial tissue characterization with cardiac CT.q RSNA, 2012

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Qual o seu diagnóstico?

Cited by 2 publications

References 7 publications

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Interstitial Myocardial Fibrosis Assessed as Extracellular Volume Fraction with Low-Radiation-Dose Cardiac CT

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