Padronização do método para cálculo da captação renal absoluta do99mTc-DMSA em cria

Ono, Carla Rachel; Sapienza, Marcelo Tatit; Machado, Beatriz Marcondes; Pahl, M M C; Liberato, Waldyr de Paula; Okamoto, Miriam Roseli Yoshie; Garcez, Alexandre Teles; Watanabe, Tomoco; Costa, P.; Buchpiguel, Carlos Alberto

doi:10.1590/s0100-39842006000100008

Cited by 3 publications

(3 citation statements)

References 19 publications

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“…The preferential accumulation of [ 99m Tc]TcDMSA 2in the renal cortex allows this tracer to remain for several hours in that region, making it possible to gather well-defined images in the SRS examination by associating functional characterization with morphological evaluation of the renal parenchyma ([ 99m Tc]TcDMSA 2allows verification not only of the presence or absence of renal scars, but also allows quantification of the renal function). It is known that [ 99m Tc]TcDMSA 2-highly accumulates in the renal cortex [35,47]. Cortical scintigraphy (SRS) is usually performed upon indication of renal scars following recurrent episodes of renal infection, typically ascending Urinary Tract Infections (UTIs) from Vesicoureteral Reflux (VUR) or secondary to urinary anomalies such as calyceal diverticulum [25].…”

Section: Resultsmentioning

confidence: 99%

A feasibility study for a new one-day protocol for [99mTc]TcDTPA2- and [99mTc]TcDMSA2- renal scintigraphy on dilated and non-dilated pediatric patients: underlying rationale

Trevisan

Nascimento²,

Chibana³

et al. 2023

Braz. J. Rad. Sci.

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Purpose. This work aimed at evaluating the possibility of performing renal exams of dynamic renal (DRS) and static renal (SRS) scintigraphy on the same day (one-day protocol, ODP), exams that are currently performed in two days. Approach. 25 infants (50 kidneys) of both genders, aged 8.4 ± 5.9 years, underwent an F+20 DRS protocol with [99mTc]TcDTPA2- followed by [99mTc]TcDMSA2- administration for the performance of SRS images at 3, 6 and 24 h. Dynamic images (DRS) were classified as dilated (D), undetermined (U), and non-dilated (P). Static images (SRS) were classified as: depressed in accented degree (DA); depressed in moderate degree (DM); depressed in mild degree (DL) and normal (NL). Results. Out of the 25 patients (50 kidneys), 7 (14 kidneys) were excluded by functional exclusion, hence 18 patients (36 kidneys) were clinically compared regarding their static images after 3, 6 and 24 h, resulting in 33.0% of dilated and 66.7% non-dilated. Only two patients of the dilated group were classified as obstructed. At the group with non-dilated and dilated but non-obstructed kidneys, 100% of them had the same clinical classification at 6 and 24 h images. Conclusions. Performance of both DRS and SRS exams in a single day for pediatric patients, when medical requests are carried out jointly, is feasible in a population with or without dilatation, when the difference between dynamic and static images is of at least 6 h. Due to the small number of obstructed kidneys in this study, further evaluation in this population is needed.

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Section: Resultsmentioning

confidence: 99%

A feasibility study for a new one-day protocol for [99mTc]TcDTPA2- and [99mTc]TcDMSA2- renal scintigraphy on dilated and non-dilated pediatric patients: underlying rationale

Trevisan

Nascimento²,

Chibana³

et al. 2023

Braz. J. Rad. Sci.

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“…Technetium-99m-labeled DMSA static renal scintigraphy (99mTc-DMSA) was evaluated according to a study proposed by Ono et al, ( 6 ) and classified as: renal uptake greater than 45%: absence of renal injury, renal uptake between 44 to 40%: mild injury, renal uptake between 39 and 35%: moderate injury and renal uptake between 34 and 30%: severe injury.…”

Section: Methodsmentioning

confidence: 99%

Study of serum and urinary markers of the reninangiotensin-aldosterone system in myelomeningocele patients with renal injury detected by DMSA

et al. 2020

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Introduction: The Renin-Angiotensin-Aldosterone System (RAAS) has been suggested as a possible marker of renal injury in chronic diseases. This study proposes to analyze the serum and urinary markers of the RAAS in myelomeningocele patients with renal function abnormalities detected on DMSA. Material and Methods: Seventeen patients followed in our institution that presented with renal injury on DMSA. We review nephrologic and urologic clinical aspects and evaluated ultrassonagraphy, voiding urethrocystography and urodynamics. Urinary and serum samples were collected to evaluate possible correlations of renal lesions with RAAS. Control group urine and serum samples were also sent for analysis. Results: Serum ACE 2 activity means in relation to urodynamic findings were the only values that had a statistically significant difference (p = 0.040). Patients with normal bladder pattern presented higher ACE 2 levels than the high risk group. Statistical analysis showed that the study group (SG) had a significantly higher mean serum ACE than the CG. The means of ACE 2 and urinary ACE of the SG and CG were not statistically different. The ROC curve for serum ACE values had a statistically significant area for case and non-case differentiation, with 100% sensitivity and 53% specificity for values above 60.2 mg/dL. No statistically significant areas were observed in relation to ACE 2 and urinary ACE values between SG and CG. Conclusion: The analysis of serum ACE, ACE 2 and urinary ACE were not significant in patients with myelomeningocele and neurogenic bladder with renal injury previously detected by renal DMSA.

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“…Assumindo-se que esta substância seja clareada somente por filtração glomerular, como no caso da inulina, a TFG pode ser aferida pela observação do ritmo de desaparecimento da substância no sangue, aparecimento da substância na urina ou pela quantidade de captação da substância nos rins (78) . O ácido etilenodiaminotetracético marcado com cromo-51 (EDTA-51 Cr) tem perfil de excreção renal semelhante ao da inulina (79) (81) , sendo indicado em consensos internacionais que as imagens podem ser feitas em intervalos acima de 2 horas após a injeção do radiofármaco (82) .…”

Section: Identificação Da Repercussão Hemodinâmica Da Estenose E Caraunclassified

Medida da filtração glomerular determinada por EDTA-51Cr antes e após a administração de captopril: avaliação de pacientes hipertensos com ou sem estenose de artéria renal

Chaves¹

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A minha querida família: Otávio, Magali, Edinir, Carol e Tavinho, por sempre acreditarem em mim. A meu marido, amigo e companheiro, Luiz, pela paciência e amor. À minha amiga Marcela, por estar sempre a meu lado. A meu amigo Juliano, por me ouvir sempre. Agradecimentos Ao Dr. Marcelo Tatit Sapienza, meu orientador e amigo, por seus ensinamentos científicos e de vida. Ao Dr. Luiz Bortolotto, por sua disponibilidade e estímulo para realização deste trabalho. Ao Dr. José Nery Praxedes, por sua receptividade e incentivo. Ao Dr. Thiago Macedo, por seu apoio e dedicação aos pacientes. Às Doutoras Carla Ono e Tomoco Watanabe, pelos conselhos. Às amigas Cristina e Miriam, pelo apoio. A Rosana, por tanto me ajudar na marcação dos exames. Aos Físicos: Silvana e Alexandre, pelos ensinamentos, disponibilidade e amizade. A Edslaine, pela colaboração constante na execução desta pesquisa. À equipe de enfermagem do Centro de Medicina Nuclear, especialmente, ao Edyr, pela grande ajuda na concretização deste trabalho. Aos biomédicos: Douglas, Leandro, João, Ana, Sayuri e Ivani, pelo apoio e incentivo durante todos esses anos. E, especialmente, aos pacientes deste estudo, pela confiança, serei eternamente grata. Normatização AdotadaEsta tese está de acordo com as seguintes normas, em vigor no momento da confecção desta tese: Referências: adaptado de International Committee of Medical Journals Editors (Vancouver)

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Padronização do método para cálculo da captação renal absoluta do99mTc-DMSA em cria

Cited by 3 publications

References 19 publications

A feasibility study for a new one-day protocol for [99mTc]TcDTPA2- and [99mTc]TcDMSA2- renal scintigraphy on dilated and non-dilated pediatric patients: underlying rationale

A feasibility study for a new one-day protocol for [99mTc]TcDTPA2- and [99mTc]TcDMSA2- renal scintigraphy on dilated and non-dilated pediatric patients: underlying rationale

Study of serum and urinary markers of the reninangiotensin-aldosterone system in myelomeningocele patients with renal injury detected by DMSA

Medida da filtração glomerular determinada por EDTA-51Cr antes e após a administração de captopril: avaliação de pacientes hipertensos com ou sem estenose de artéria renal

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