Peripheral eosinophilia as an indicator of meningitic angiostrongyliasis in exposed individuals

Sawanyawisuth, Kittisak; Sawanyawisuth, Kanlayanee; Senthong, Vichai; Limpawattana, Panita; Intapan, Pewpan M.; Tiamkao, Somsak; Jitpimolmard, Suthipun; Chotmongkol, Verajit; Barrett‐Connor, Elizabeth

doi:10.1590/s0074-02762010000700020

Cited by 13 publications

(13 citation statements)

References 7 publications

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“…Compared to adult patients [5], a higher proportion of children showed cranial nerve abnormalities (both cranial nerve VI and VII), neck stiffness (68.4% vs 47.5%), and papilledema (31.6% vs 2.5%). Clinical signs of meningism (fever, headache, and neck stiffness) were much more frequent in child patients compared with adults (68.4% vs 9.0%).…”

Section: Discussionmentioning

confidence: 99%

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Clinical Manifestations of Eosinophilic Meningitis Due to Infection with Angiostrongylus cantonensis in Children

et al. 2013

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Eosinophilic meningitis, caused by the nematode Angiostrongylus cantonensis, is prevalent in northeastern Thailand, most commonly in adults. Data regarding clinical manifestations of this condition in children is limited and may be different those in adults. A chart review was done on 19 eosinophilic meningitis patients aged less than 15 years in Srinagarind Hospital, Faculty of Medicine, Khon Kaen University, Thailand. Clinical manifestations and outcomes were reported using descriptive statistics. All patients had presented with severe headache. Most patients were males, had fever, nausea or vomiting, stiffness of the neck, and a history of snail ingestion. Six patients had papilledema or cranial nerve palsies. It was shown that the clinical manifestations of eosinophilic meningitis due to A. cantonensis in children are different from those in adult patients. Fever, nausea, vomiting, hepatomegaly, neck stiffness, and cranial nerve palsies were all more common in children than in adults.

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Section: Discussionmentioning

confidence: 99%

“…A typical presenting symptom of EOM is acute severe headache without neurological deficits [4]. The diagnosis may be missed because meningism signs including fever and neck stiffness are found infrequently [5]. EOM in children is rarely reported in the literature.…”

Section: Introductionmentioning

confidence: 99%

Clinical Manifestations of Eosinophilic Meningitis Due to Infection with Angiostrongylus cantonensis in Children

et al. 2013

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“…suggests parasitic infestation. [4] Commonest causes of eosinophilic meningitis are angiostrongyliasis (rat lung worm) and gnathostomiasis worldwide. [5] In India, eosinophilic meningitis has been reported in 2 case series [6,7] and 2 case reports [8,9] and has not been reported in children below 15 years of age.…”

Section: Introductionmentioning

confidence: 99%

“…[2,3] In the UK, since the incorporation of Hib vaccine into routine immunization, the attack rate has decreased from 20-40 to 1 per 100,000 children under the age of 5 years. [4] Vaccine failure after regular Hib vaccination is rare. We report a 14-month-male child who developed H. infl uenzae meningitis and septicaemia after primary immunisation with three doses of the conjugate vaccine.…”

Section: Introductionmentioning

confidence: 99%

Eosinophilic meningitis: A case series and review of literature of Angiostrongylus cantonensis and Gnathostoma spinigerum

Shah

Barot

Madvariya

2015

Indian Journal of Medical Microbiology

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Eosinophilic meningitis is defined as the presence of >10 eosinophils/μL in cerebrospinal fluid (CSF) or at least 10% eosinophils in the total CSF leukocyte count. Eosinophilic meningitis has been reported in two case series and two case reports in India till date and has not been reported in children below 15 years of age. We present two children with eosinophilic meningitis with peripheral eosinophilia and the proposed etiologic agents based on the clinical setting and their response to antihelminthic agents.

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“…An initial complete blood count assessment is recommended in patients suspected of having EoM. Peripheral eosinophilia is common; an eosinophil count > 798 in an individual at risk (e.g., due to a history of raw mollusc consumption) has shown 76.6% sensitivity, 80.2% specificity, a 58.1% positive predictive value and an 90.5% negative predictive value, which support the diagnosis of CA (Sawanyawisuth et al 2010). …”

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confidence: 99%

Eosinophilic meningitis caused by Angiostrongylus cantonensis: an emergent disease in Brazil

Morassutti

Thiengo

Fernandez

et al. 2014

Mem. Inst. Oswaldo Cruz

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108

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Eosinophilic meningitis (EoM) is an acute disease that affects the central nervous system. It is primarily caused by infection with the nematode Angiostrongylus cantonensis. This infection was previously restricted to certain Asian countries and the Pacific Islands, but it was first reported in Brazil in 2007. Since then, intermediate and definitive hosts infected with A. cantonensis have been identified within the urban areas of many states in Brazil, including those in the northern, northeastern, southeastern and southern regions. The goals of this review are to draw the attention of the medical community and health centres to the emergence of EoM in Brazil, to compile information about several aspects of the human infection and mode of transmission and to provide a short protocol of procedures for the diagnosis of this disease.

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Peripheral eosinophilia as an indicator of meningitic angiostrongyliasis in exposed individuals

Cited by 13 publications

References 7 publications

Clinical Manifestations of Eosinophilic Meningitis Due to Infection with Angiostrongylus cantonensis in Children

Clinical Manifestations of Eosinophilic Meningitis Due to Infection with Angiostrongylus cantonensis in Children

Eosinophilic meningitis: A case series and review of literature of Angiostrongylus cantonensis and Gnathostoma spinigerum

Eosinophilic meningitis caused by Angiostrongylus cantonensis: an emergent disease in Brazil

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