Current profile of Mansonella ozzardi (Nematoda: Onchocercidae) in communities along the Ituxi river, Lábrea municipality, Amazonas, Brazil

Medeiros, Jansen Fernandes; Py-Daniel, Victor; Barbosa, Ulysses Carvalho; Ogawa, Guilherme Maerschner

doi:10.1590/s0074-02762008000400017

Cited by 36 publications

(44 citation statements)

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“…These similar prevalence rates could be the result of similar exposure levels between sexes. In addition, our results are in agreement with those of Batista et al 5 , Shelley 6 , and Medeiros et al 7 , who found no statistically significant difference in the prevalence rates between sexes. However, other epidemiological studies have reported a higher disparity between the prevalence rates in males and females 4,8 .…”

Section: Abstract Introductionsupporting

confidence: 94%

Mansonella ozzardi (Nematoda: Onchocercidae) in the riverine population of the Tefé River, State of Amazonia, Brazil

Medeiros

Costa

Lima

et al. 2014

Rev. Soc. Bras. Med. Trop.

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Revista da Sociedade Brasileira de Medicina ABSTRACT Introduction:This study assessed the prevalence of Mansonella ozzardi in riverine communities of the Tefé River, Amazonas, Brazil. Methods: The prevalence of M. ozzardi was estimated by microscopic examination of thick blood smears. Results: The M. ozzardi prevalence rate was 6.3% (19/300). Filarial infection was found in 8 of the 11 communities surveyed, with prevalence rates varying from 2.5% to 22.2%. Conclusions: Tefé is a region of oil and natural gas exploration, in which there is a high turnover of workers. Migration patterns may facilitate the dissemination of mansonelliasis to other regions.Keywords: Mansonella ozzardi. Tefé River. Amazonas.An epidemiological survey of mansonelliasis was conducted in Tefé, State of Amazonas, Brazil, in the 1950s and reported a prevalence rate between 2.5% and 18.7% for Mansonella ozzardi 1 . However, no other surveys have been conducted in this region, and current knowledge pertaining to the occurrence of mansonelliasis is based on records from the Foundation Surveillance Health (FVS) in Tefé obtained during a routine malaria survey (JF Medeiros: personal information). In Tefé, there is a significant population of migrant workers who are employed at companies that extract oil and natural gas. These companies employ many workers from regions without mansonelliasis, and this migration demonstrates the potential for the spread of mansonelliasis to non-endemic regions when these migrant workers return to their native communities. This study was the first survey of human filarial mansonelliasis in the Tefé River region of oil and gas production, and it was conducted to investigate the prevalence of M. ozzardi among the resident population of the Tefé River region.The present study was conducted among people living along the Tefé River in the municipality of Tefé (3°30'S 64°58'W), State of Amazonas, Brazil. The Tefé River, a tributary of the Solimões River, is an area rich in oil and gas, with continuous mineral extraction (Figure 1). The population density of the area is low, and the people live in small communities dispersed along the riverbanks and generally practice subsistence farming (fishing and agriculture).The work presented here was part of a pilot study to provide baseline data for the design of future, more detailed studies. Individuals present at the initiation of the study were informed of the purpose and scope of the study and were invited to participate. Informed verbal consent to participate in the study was obtained from adult participants and the parents of child participants during community meetings. According to the Foundation of Surveillance in Health in Tefé, the population along the Tefe River numbers approximately 850. A total of 300 individuals (~35% of the population) between the ages of 2 and 82 years were included in this study and examined by rapid epidemiological mapping for microfilariae of M. ozzardi in June 2012. This study received approval from the Ethical Committee of the Tropical Medic...

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Section: Abstract Introductionsupporting

confidence: 94%

Mansonella ozzardi (Nematoda: Onchocercidae) in the riverine population of the Tefé River, State of Amazonia, Brazil

Medeiros

Costa

Lima

et al. 2014

Rev. Soc. Bras. Med. Trop.

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“…There is a question of whether the diagnosis method used in this study was not sensitive enough to detect low rates of microfilaremia. However, many studies carried out in the Amazon use the same method and show prevalence of up to 60% of microfilaremia [7][8][9] . Another hypothesis may be that there are not enough individuals infected with a high enough parasite load to disseminate this endemic disease in areas not affected by the infection.…”

Section: Discussionmentioning

confidence: 99%

“…A similar phenomenon may have occurred with regard to current M. ozzardi infection in terms of the lack of occurrence of mansonelliasis foci in this region. The existence of competent vectors and the proximity of a hyper-endemic area with regard to the occurrence of M. ozzardi (Lábrea, AM) 8 as well as the absence of this parasitic disease in Rondônia has been noted.…”

Section: Discussionmentioning

confidence: 99%

“…Labrea and Humaita (LMA Camargo: personal information), which are endemic areas for mansonelliasis 8,17 . Thus, further studies to find possible foci of mansonelliasis in the region are necessary.…”

Section: Basano Sm Et Al -Mansonelliasis In Rondônia Brazilmentioning

confidence: 99%

“…Later, some researchers observed individuals infected with M. ozzardi alongside the Solimoes, Purus and Negro Rivers in the State of Amazonas [4][5][6] . Recent data have indicated that this parasite is still found with high prevalence rates in the Amazonian territory [7][8][9] .…”

Section: Introductionmentioning

confidence: 99%

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Investigação da ocorrência da Mansonella ozzardi no Estado de Rondônia, Amazônia Ocidental

Basano

Camargo

Vera

et al. 2011

Rev. Soc. Bras. Med. Trop.

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Introduction: Mansonella ozzardi, a human filarial nematode transmitted by Diptera Simuliidae flies (black flies), is widely spread in the Amazon, while the occurrence of mansonelliasis in the State of Rondônia (Western Amazonia) has not been reported thus far. The existence of this parasitic disease in this state is investigated in this study. Methods: A total of 4,452 people who lived alongside the Madeira, Mamore, Guapore, Machado and Preto Rivers, in the State of Rondônia, were examined using the thick blood smear method. Alongside the Machado and Guapore rivers, 2,112 adult simuliid specimens were captured. Results: Infected people were not reported, although simuliids with vector potential such as Cerqueirellum pydanielli, C. argentiscutum and C. amazonicum were found. Conclusions: This study registered no infected people. This finding may be explained by the individuals' low level of microfilaremia that is below the limit of detection of the diagnostic method used in the study or insufficient migration of people infected with M. ozzardi from endemic areas, making it impossible to introduce the disease into Rondônia. Further studies using more sensitive diagnostic techniques could shed light on this question.Keywords: Mansonella ozzardi. Microfilariae. Simuliidae. State of Rondônia. RESUMOIntrodução: Mansonella ozzardi é uma filária humana que tem como vetor dípteros simulídeos e é amplamente distribuída na Amazônia. Não há informações sobre a ocorrência de casos de mansonelose no Estado de Rondônia, e neste trabalho procurou-se investigar a situação epidemiológica desta parasitose em áreas urbanas e ribeirinhas na Amazônia Ocidental. Métodos: Foram examinados 4.452 moradores às margens dos rios Madeira, Mamoré, Guaporé, Machado e Preto em Rondônia, através da técnica da gota espessa de sangue. Capturou-se às margens do rio Machado e Guaporé 2.112 simulídeos adultos das espécies Cerqueirellum pydanieli e Chirostilbia pertinax. Resultados: Não foram encontradas pessoas infectadas com M. ozzardi e foram encontradas diferentes espécies de simulídeos com potencial de transmissão da mansonelose. Conclusões: Não foram encontrados indivíduos infectados com M. ozzardi neste estudo. Este fato pode ser explicado pela existência de pacientes com baixas microfilaremias, associado à técnica diagnóstica de baixa sensibilidade utilizada no estudo. Pode-se ainda aventar a possibilidade de ter ocorrido migração insuficiente de pacientes infectados de áreas endêmicas, impossibilitando a implantação da endemia. Estudos posteriores com técnicas diagnósticas mais sensíveis podem ajudar a esclarecer esta questão. Palavras-chaves:Mansonella ozzardi. Microfilárias. Simuliidae. Rondônia.

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Mansonelliasis

Medeiros¹,

Crainey²,

Pessoa³

et al. 2016

Arthropod Borne Diseases

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Current profile of Mansonella ozzardi (Nematoda: Onchocercidae) in communities along the Ituxi river, Lábrea municipality, Amazonas, Brazil

Cited by 36 publications

References 6 publications

Mansonella ozzardi (Nematoda: Onchocercidae) in the riverine population of the Tefé River, State of Amazonia, Brazil

Mansonella ozzardi (Nematoda: Onchocercidae) in the riverine population of the Tefé River, State of Amazonia, Brazil

Investigação da ocorrência da Mansonella ozzardi no Estado de Rondônia, Amazônia Ocidental

Mansonelliasis

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