Association of insecticide use and alteration on Aedes aegypti susceptibility status

Macoris, Maria de Lourdes da Graça; Andrighetti, Maria Teresa Macoris; Otrera, Vanessa Camargo Garbeloto; Carvalho, Lídia Raquel de; Júnior, Antônio Luiz Caldas; Brogdon, William G.

doi:10.1590/s0074-02762007000800001

Cited by 58 publications

(60 citation statements)

References 13 publications

(12 reference statements)

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“…Temephos resistance was even found in Cuiabá in contrast to an earlier report from that locality (Campos & Andrade 2003), suggesting recent local resistance dissemination (MS/SVS 2007). High temephos RR values were found at localities from Northeast and Southeast Brazil, corroborating previous data , Macoris et al 2007, Montella et al 2007). Strikingly, the Henrique jorge population exhibited very high RR levels, although these assays were performed with specimens reared in the laboratory for three generations without insecticides.…”

Section: Discussionsupporting

confidence: 91%

The efficacy of a chitin synthesis inhibitor against field populations of organophosphate-resistant Aedes aegypti in Brazil

Fontoura

Bellinato

Valle

et al. 2012

Mem. Inst. Oswaldo Cruz

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Key words: Aedes aegypti -chitin synthesis inhibitors -temephos -deltamethrin -novaluron -cross-resistance Among the arboviruses transmitted by mosquitoes throughout the world, dengue is presently the most relevant; it is endemic to all of the continents, except Europe (Nogueira et al. 2001, Forattini 2002, Claro et al. 2004. Brazil has an alarming dengue incidence with several outbreaks all over the country and an increasing incidence of severe cases. Therefore, major public health campaigns target this disease (Teixeira et al. 1999, Câ-mara et al. 2007, MS/SVS 2009.Specific drugs and an effective vaccine against dengue virus are not yet available (Durbin & Whitehead 2010). Consequently, the only way to control the dengue epidemiological network is to target the virus' vector, Aedes aegypti (Medronho 2006. Although the elimination of potential Aedes breeding sites is increasingly considered a crucial component of dengue control, the utilisation of chemical insecticides is still a common measure. Until very recently, the most commonly used insecticides against Aedes in Brazil were the organophosphate temephos and the pyrethroid deltamethrin, which are used to control the larval and adult populations, respectively .The continuous use of chemical insecticides can lead to the dissemination of resistance and the consequent failure of the control efforts. Therefore, alternative methods of controlling disease-transmitting vectors are urgently needed. Two examples are entomopathogenic bacteria and insect growth regulators (IGRs). The biological insecticide Bacillus thuringiensis serovar israelensis (Bti) has been employed against Ae. aegypti in various municipalities of Brazil. However, the reduced field persistence of commercially available Bti formulations is an obstacle; under tropical conditions, the maximal residual effect observed lasted four weeks .In contrast to the classical chemical insecticides and biolarvicides, IGRs are not directly toxic, but act selectively on the development, metamorphosis or reproduction of the target insect species (Hoffmann & Lorenz 1998, Martins & Silva 2004. Among IGRs, the chitin synthesis inhibitors (CSIs) act by interfering with the synthesis or deposition of chitin on the exoskeleton or other chitinised internal structures, such as the peritrophic matrix (Merzendorf & Zimoch 2003, Merzendorf 2005.Novaluron is a CSI that is already utilised in agriculture. It is highly effective against Coleoptera, Homoptera and Lepidoptera larvae of several crop pests . It can act through ingestion, as verified in the larvae of the moth species Spodoptera littoralis and Helicoverpa armigera, or through contact, as reported with the flies Bemisia tabaci and Trialeurodes vaporariorum (Ishaaya et al. 1996(Ishaaya et al. , 1998. Novaluron is also efficient against Ae. aegypti larvae, as reported by Mulla et al. (2003) and Arredondo-jiménez and Valdez-Delgado (2006). Because novaluron is recommended by the World Health Organization for use in drinking water, it represents a potential tool in the con...

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Section: Discussionsupporting

confidence: 91%

The efficacy of a chitin synthesis inhibitor against field populations of organophosphate-resistant Aedes aegypti in Brazil

Fontoura

Bellinato

Valle

et al. 2012

Mem. Inst. Oswaldo Cruz

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“…Several studies have demonstrated successive increases in resistance to pyrethroid insecticides over time in dengue vectors, often following repeated applications of this insecticide class for dengue control (9,29,30). Furthermore, a cagebioassay in the Caribbean island of La Martinique demonstrated that the efficacy of deltamethrin applied by a vehicle thermal fogger was compromised by resistance in the local Ae.…”

Section: Impact Of Current Levels Of Insecticide Resistance On Vectormentioning

confidence: 99%

Temporal and Spatial Distribution of Dengue Vector Mosquitoes and their Habitat Patterns in Penang Island, Malaysia

Saifur

Hassan

Dieng

et al. 2013

Journal of the American Mosquito Control Association

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“…Since there is no vaccine currently available for dengue and DHF prevention, the eradication of the mosquito adults and larvae, which is primarily relied on applications of synthetic insecticides or larvicides, is the most commonly adopted strategy for reducing morbidity (WHO, 2008). According to the literature, the organophosphate temephos is one of the most employed commercial insecticides for the control of this vector (Macoris et al, 2007;Garcez et al, 2009;Oliveira et al, 2010). However, these chemicals can affect non target population and may increase mosquito resistance to insecticides.…”

Section: Resultsmentioning

confidence: 99%

Chemical Constituents, Larvicidal Effects and Radical Scavenging Activity of Tetracera breyniana Schltdl. (Dilleniaceae)

2013

J App Pharm Sci

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Extracts and fractions from the leaves and stems of Tetracera breyniana Schltdl. were evaluated against the fourth instar Aedes aegypti larvae and ability to scavenge free radicals. Fractions that provided the best results were fractionated on silica gel column to afforded three flavonoils (quercetin, 7-O-methylquercetin and 7-Omethylkaempferol) and two terpenoids (β-sitosterol and betulinic acid). These compounds were identified on basis of their physical and NMR spectral data and by comparison with literature data. With exception of quercetin, all other compounds are been described for the first time in the investigated species. In the larvicidal assays, when compared to synthetic insecticide Temephos, only hexane fraction from stem was effective (LD50 72.08 g/mL). In the DPPH assays, EtOAc fractions from the leaves (CI50 74.15 ± 14.73 g/mL) and stem (IC50 39.87 ± 13.46 g/mL), of which quercetin was isolated, showed the best results when compared with the positive standards used while CHCl3 fractions of both plant parts, of which methylated flavonols were isolated, showed only a moderate activity. Possibly these constituents are responsible in part for the radical scavenging activities observed. Subsequently, evaluation of all isolated compounds will be needed to confirm the active component.

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Association of insecticide use and alteration on Aedes aegypti susceptibility status

Abstract: Dengue and dengue hemorrhagic fever, vector-borne diseases transmitted by the mosquito

Cited by 58 publications

References 13 publications

The efficacy of a chitin synthesis inhibitor against field populations of organophosphate-resistant Aedes aegypti in Brazil

The efficacy of a chitin synthesis inhibitor against field populations of organophosphate-resistant Aedes aegypti in Brazil

Temporal and Spatial Distribution of Dengue Vector Mosquitoes and their Habitat Patterns in Penang Island, Malaysia

Chemical Constituents, Larvicidal Effects and Radical Scavenging Activity of Tetracera breyniana Schltdl. (Dilleniaceae)

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