Frequency of serovars and antimicrobial resistance in Shigella spp. from Brazil

Peirano, Gisele; Souza, Flávia dos Santos; Rodrigues, Dália dos Prazeres

doi:10.1590/s0074-02762006000300003

Cited by 30 publications

(37 citation statements)

References 22 publications

(24 reference statements)

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“…The data shown in this study are consistent with data 4,13,17,18 shown for other states of Brazil and other countries from Central America, North America, Africa, Middle East 19 and India as described by Drews et al, 2010 .…”

Section: Discussionsupporting

confidence: 93%

“…In addition to several other studies performed in 4 Brazil, Peirnano et al analyzed Shigella isolates from the period of 1999 to 2004 and reported the prevalence of S. flexneri (52.7%) over S. sonnei (4.2%). The highest rates of isolation of this enteric pathogen were observed in the southeastern region (39%), followed by the northeastern region (34%) and a slight occurrence in the Southern region (3%) of the country.…”

Section: Introductionmentioning

confidence: 99%

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Caracterização da resistência antimicrobiana de amostras de Shigella spp. isoladas em Belém, Estado do Pará, Brasil (1990-2000)

Bastos¹,

Loureiro²

2010

Rev Pan-Amaz Saude

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Section: Discussionsupporting

confidence: 93%

Section: Introductionmentioning

confidence: 99%

Caracterização da resistência antimicrobiana de amostras de Shigella spp. isoladas em Belém, Estado do Pará, Brasil (1990-2000)

Bastos¹,

Loureiro²

2010

Rev Pan-Amaz Saude

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“…It is responsible for approximately 165 million cases of diarrhea annually, of which 163 million are in developing countries and 1.5 million are in industrialized ones (4,5). In developing countries, 69% of all cases are children under the age of 5 years (6,7).…”

Section: Introductionmentioning

confidence: 99%

Prevalence of Shigella species and Antimicrobial Resistance Patterns of Isolated Strains from Infected Pediatrics in Tehran

Mardaneh¹,

Poor²,

Afrugh³

2013

Int J Enteric Pathog

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Background:Shigella is an infectious food-borne pathogen that can cause a severe diarrhea illness called shigellosis. The increasing levels of antimicrobial resistance of Shigella isolates have complicated the treatment of shigellosis. The antimicrobial resistance patterns of Shigella species vary according to geographic region and in the same place over time, leading to a therapeutic problem. Objectives: This study attempts to determine the prevalence of shigellosis and the antimicrobial susceptibility pattern of isolated strains. Materials and Methods:This cross-sectional study, with a 12-month duration, between August 2010 and August 2011 was carried out on 9131 infants with acute diarrheal disease. Stool samples were inoculated on selective and differential media. The Shigella isolates were identified and confirmed by biochemical laboratory tests. Subsequently, serotyping was performed with group specific antisera. Drug sensitivity test was carried out according to CLSI (2010) recommendations by using the standard disc diffusion method. Results: Shigella spp. were isolated from 90 (1%) of the 9131 stool samples collected from children with acute diarrhea. Among Shigella isolates, the most common subgroup was S. sonnei 63 (70%). Our results showed that imipenem, ciprofloxacin, ceftazidime and ceftizoxime are most effective antimicrobial agents against Shigellasp. The most frequent resistance observed, was towards co-trimoxazole (92.2%), ampicillin (65.6%) and tetracycline (65.6%) Conclusion: Since antibiotic resistant profile of Shigella varies geographically and also over time within a single country, regular, continuous surveillance is necessary. The results of accurate surveillance should be used to guide policies for antibiotic prescription.

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“…S. sonnei strains tend to cause milder illness than S. flexneri, persist in both developed and developing countries and tend to cause sporadic diarrhea and occasional outbreaks in specific epidemiological niches, such as daycare centers, where personal hygiene may be suboptimal (8,14). In Brazil, a few studies (4,9,11) indicate that shigellosis cases are underestimated, with S. flexneri and S. sonnei strains being the major pathogenic agents (11).…”

Section: Introductionmentioning

confidence: 99%

Molecular epidemiology of Shigella spp strains isolated in two different metropolitam areas of southeast Brazil

Angelini¹,

Stehling²,

Moretti³

et al. 2009

Braz. J. Microbiol.

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Shigella spp., the human pathogen responsible for shigellosis, is highly infectious even at low levels. The incidence rate of shigellosis varies with geographical distribution, location human development index, and age groups, being higher among children aged under 5 years. In Brazil, a few works indicate that shigellosis cases are underestimated, with S. flexneri and S. sonnei strains being the major agents responsible for the shigellosis cases. The present study used pulsed field gel electrophoresis (PFGE) to investigate the molecular epidemiology of 119 strains of S. sonnei and S. flexneri isolated from shigellosis cases that occurred in the metropolitan areas of Ribeirão Preto and Campinas Cities, São Paulo Sate, southeast Brazil. The results indicated (i) the existence of just a few strain clusters for both species, but with genotype variability with either a high speed of genetic change or constant introduction of several genotypes, considering the intense migration to these two metropolitan areas, and (ii) the prevalence of specific genotypes in each geographical area, which suggests the successful adaptation of some genotypes to the local environmental conditions. Our results indicate the need of more efficacious sanitary barriers to prevent Shigella spp. outbreaks and epidemics.

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Frequency of serovars and antimicrobial resistance in Shigella spp. from Brazil

Cited by 30 publications

References 22 publications

Caracterização da resistência antimicrobiana de amostras de Shigella spp. isoladas em Belém, Estado do Pará, Brasil (1990-2000)

Caracterização da resistência antimicrobiana de amostras de Shigella spp. isoladas em Belém, Estado do Pará, Brasil (1990-2000)

Prevalence of Shigella species and Antimicrobial Resistance Patterns of Isolated Strains from Infected Pediatrics in Tehran

Molecular epidemiology of Shigella spp strains isolated in two different metropolitam areas of southeast Brazil

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