Toxicity of pyrethroids and repellency of diethyltoluamide in two deltamethrin-resistant colonies of Triatoma infestans Klug, 1834 (Hemiptera: Reduviidae)

Sfara, Valeria; Zerba, Eduardo; Alzogaray, Raúl A.

doi:10.1590/s0074-02762006000100017

Cited by 31 publications

(15 citation statements)

References 21 publications

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“…Most studies focus their attention on the repellency response of haematophagous insects, particularly mosquitoes. The effect of DEET on Triatomines has been described by our laboratory for T. infestans (Alzogaray et al, 2000;Sfara et al, 2006). These results show that DEET doses between 7 and 700 µg/cm 2 are repellent for T. infestans nymphs.…”

Section: Discussionsupporting

confidence: 62%

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Decrease in DEET repellency caused by nitric oxide in Rhodnius prolixus

Sfara

Zerba

Alzogaray

2007

Arch Insect Biochem Physiol

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N,N-diethyl-3-methylbenzamide (DEET) is widely used as an insect repellent; however, little is known about its mode of action. On the other hand, nitric oxide (NO) participates in the olfaction transduction pathway of insects. In this work, nitroso-acetyl-cysteine (SNAC), a nitric oxide donor, or dibutyril-cyclic-GMP (db-cGMP), the cyclic nucleotide analog, were applied on fifth instar nymphs of Rhodnius prolixus before exposing them to DEET, to obtain information about the possible role of NO/cGMP system in the olfaction process. In the first place, we exposed the nymphs to several DEET concentrations (70, 700, 1,750, and 3,500 microg/cm2). All these concentrations produced a repellent effect. A decrease in repellency during the course of the experiment was observed when the nymphs were exposed to high concentrations of DEET (700 and 1,750 microg/cm2), suggesting an adaptation phenomenon. The pre-treatment of the insects with 15 microg /insect of SNAC or 2 microg/insect of db-cGMP produced a reduction of the repellency. An increase in locomotor activity was observed in insects exposed to 350 or 700 microg/cm2 DEET. Although exposure to 70 microg/cm2 DEET produced a high repellency response, it did not modify the insects' locomotor activity. Insects treated with two doses of SNAC before being exposed to 350 microg/cm2 of DEET showed no differences in locomotor activity compared to controls.

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Section: Discussionsupporting

confidence: 62%

“…DEET has also shown a repellent effect in Triatoma infestans, (Alzogaray et al, 2000;Sfara et al, 2006). In these studies, it was observed that pretreatment of T. infestans nymphs with the sulphydryl reagent N-ethylmaleimide (NEM), decreased the repellent effect of DEET (Alzogaray et al, 2000).…”

Section: Introductionmentioning

confidence: 99%

Decrease in DEET repellency caused by nitric oxide in Rhodnius prolixus

Sfara

Zerba

Alzogaray

2007

Arch Insect Biochem Physiol

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“…In previous years, resistance to pyrethroids has been reported in T. infestans populations from Argentina and Bolivia (Picollo et al, 2005; Roca-Acevedo, Picollo & Santo-Orihuela, 2013). The individuals from these populations are resistant to both knock down and hyperactivation produced by pyrethroids (Sfara, Zerba & Alzogaray, 2006). It is therefore highly important to identify alternative flushing out agents.…”

Section: Discussionmentioning

confidence: 99%

Toxicity, repellency and flushing out in Triatoma infestans (Hemiptera: Reduviidae) exposed to the repellents DEET and IR3535

Reynoso

Seccacini

Calcagno

et al. 2017

PeerJ

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DEET and IR3535 are insect repellents present worldwide in commercial products; their efficacy has been mainly evaluated in mosquitoes. This study compares the toxicological effects and the behavioral responses induced by both repellents on the blood-sucking bug Triatoma infestans Klug (Hemiptera: Reduviidae), one of the main vectors of Chagas disease. When applied topically, the Median Lethal Dose (72 h) for DEET was 220.8 µg/insect. Using IR3535, topical application of 500 µg/insect killed no nymphs. The minimum concentration that produced repellency was the same for both compounds: 1,15 µg/cm2. The effect of a mixture DEET:IR3535 1:1 was similar to that of their pure components. Flushing out was assessed in a chamber with a shelter containing groups of ten nymphs. The repellents were aerosolized on the shelter and the number of insects leaving it was recorded for 60 min. During that time, 0.006 g/m3 of the positive control tetramethrin flushed out 76.7% of the nymphs, while 1.76 g/m3 of DEET or IR3535 flushed out 30 and 0%, respectively. The concentrations required for both compounds to produce toxicity or flushing out are too high to have any practical applications. However, they showed a promising repellency. Additional research should be done to evaluate their possible use for personal protection against T. infestans bites.

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“…The first observable indication of intoxication in many insects treated with sub‐lethal doses of pyrethroids, including Platynus assimilis , is an increase in their LA in terms of time in movement, mean velocity and walked distance . The laboratory video tracking technique has demonstrated that brief, sub‐lethal exposures to the neurotoxic pyrethroid insecticide Fastac ® 50EC over a wide range of concentrations (0.01 to 100 mg L −1 as alpha‐cyp), may cause significant alterations in the GMA and LA of the carabid beetle Platynus assimilis .…”

Section: Discussionmentioning

confidence: 99%

Sub-lethal effects of the neurotoxic pyrethroid insecticide Fastac® 50EC on the general motor and locomotor activities of the non-targeted beneficial carabid beetlePlatynus assimilis(Coleoptera: Carabidae)

Tooming¹,

Merivee

Must

et al. 2013

Pest. Manag. Sci.

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Conspicuous changes in motor activity of Platynus assimilis beetles treated at alpha-cypermethrin concentrations up to 75,000-fold lower than maximum field recommended concentration (MFRC) suggest that many, basic fitness-related behaviours might be severely injured as well. These changes may negatively affect carabid populations in agro-ecosystems. Long-term hypo-activity could directly contribute to decreased trap captures of carabids frequently observed after insecticide application in the field.

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Toxicity of pyrethroids and repellency of diethyltoluamide in two deltamethrin-resistant colonies of Triatoma infestans Klug, 1834 (Hemiptera: Reduviidae)

Abstract: The aim of the currrent investigation was to evaluate (a) the toxicity of three pyrethroids (deltamethrin, lambdacyhalothrin, and tetramethrin); (b)

Cited by 31 publications

References 21 publications

Decrease in DEET repellency caused by nitric oxide in Rhodnius prolixus

Decrease in DEET repellency caused by nitric oxide in Rhodnius prolixus

Toxicity, repellency and flushing out in Triatoma infestans (Hemiptera: Reduviidae) exposed to the repellents DEET and IR3535

Sub-lethal effects of the neurotoxic pyrethroid insecticide Fastac® 50EC on the general motor and locomotor activities of the non-targeted beneficial carabid beetlePlatynus assimilis(Coleoptera: Carabidae)

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