Report of the Fifth Brazilian Symposium on HIV/AIDS Research

Bongertz, Vera; Bou-Habib, Dumith Chequer; Castello-Branco, L.R.R.; Morgado, Mariza G.

doi:10.1590/s0074-02762005000100013

Cited by 3 publications

(4 citation statements)

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“…12 The levels of viral resistance to HAART are still relatively low in Brazil (6.6%), when compared with the rates in the United States (15%-26%), Spain (26%), and United Kingdom (14%). 13 Several factors are known to reduce adherence to HAART, including psychological distress, 14 substance use, 15 and individual characteristics, such as young age, 12 limited income, 16 and low educational levels. 17 There is an increasing tendency to expand the levels of care to people living with HIV and AIDS (PLWHA) by transcending the concept of adherence to ARV medications to also focus on engagement in medical care as an important outcome.…”

Section: Introductionmentioning

confidence: 99%

Retention in Medical Care and Antiretroviral Treatment according to Skin Color in Southern Brazil

Zúbaran

Michelim

Foresti³

et al. 2013

J Int Assoc Provid AIDS Care

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The aim of this study was to compare the retention in medical care and antiretroviral (ARV) treatment of individuals living with HIV and AIDS to antiretroviral therapy in southern Brazil according to their "race" or skin color. This study is part of a 225-day prospective trial, comprising 7 interviews, in which an intervention designed to improve adherence to treatment was tested. A convenience sample of 73 individuals living with HIV and/or AIDS enrolled in this follow-up procedure. The mean length of continuance in treatment was 161.5 (standard deviation [SD] = 18.6; 95% confidence interval [CI] = 125-198) and 138.4 (SD = 14.1; 95% C.I. = 111-166) days in the "nonwhite" and "white" categories, respectively. There was no significant difference between the 2 categories, χ(2)(1, n = 72) = 0.76, P = .38, which include similar levels of retention in medical care and treatment with ARV medications between groups of individuals categorized as white and nonwhite in this sample.

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Section: Introductionmentioning

confidence: 99%

Retention in Medical Care and Antiretroviral Treatment according to Skin Color in Southern Brazil

Zúbaran

Michelim

Foresti³

et al. 2013

J Int Assoc Provid AIDS Care

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“…1 Thus, considering that the Brazilian population is approximately 200 million inhabitants, there are 1.3 million of Brazilians living with this condition. In Brazil there is universal access to antiretroviral drugs (ARVs) and combination antiretroviral therapy (ART), which has been publicly funded since 1996.…”

Section: Introductionmentioning

confidence: 99%

“…20 However, in comparison with the rates in the USA (15 -26%), Spain (26%) and the UK (14%), there are low levels of viral resistance to cART in Brazil (6.6%). 1 Several factors are known to reduce adherence to cART, including individual characteristics, such as young age, 20 limited income, 21 low educational levels, 9 psychological distress 22 and substance use. 23 Official guidelines proposed by the BMH in relation to ART indicate that the most important factors associated with adherence include patient's confidence in treatment, appropriate social support, doctor's experience and attendance at regular follow-up appointments.…”

Section: Introductionmentioning

confidence: 99%

“…A report issued by the Brazilian Ministry of Health (BMH) National Program on HIV and Sexually Transmitted Diseases estimated that 0.65% of the Brazilian population is infected by HIV-1. 1 Thus, considering that the Brazilian population is approximately 200 million inhabitants, there are 1.3 million of Brazilians living with this condition. In Brazil there is universal access to antiretroviral drugs (ARVs) and combination antiretroviral therapy (ART), which has been publicly funded since 1996.…”

Section: Introductionmentioning

confidence: 99%

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A randomized controlled trial of a protocol of interviews designed to improve adherence to antiretroviral medications in southern Brazil

et al. 2012

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The aim of this study was to evaluate the efficacy of the Portuguese version of the Medication Adherence Training Instrument (MATI) for improving adherence to antiretroviral therapy (ART) in southern Brazil. Two different follow-up modalities were compared in this 225 days randomized controlled study: one based on the MATI protocol and a conventional (non-MATI) clinical follow-up. There were no differences between the groups with the exception of socioeconomic class (P < 0.005). The mean length of continuance in treatment was 111.4 (SD = 13.9) and 137.6 (SD = 17.3) days in the MATI and non-MATI groups, respectively. A Mantel-Cox log-rank test revealed no significant difference between the two interventions (P = 0.34). Despite the sample size limitation, the results from this study indicate that the Portuguese version of the MATI was not more efficacious than the regular follow-up intervention for improving adherence of outpatients to ART.

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Role of iron overload-induced macrophage apoptosis in the pathogenesis of peritoneal endometriosis

Pirdel¹,

Pirdel²

2014

Reproduction

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This article presents an overview of the involvement of iron overload-induced nitric oxide (NO) overproduction in apoptosis of peritoneal macrophages of women with endometriosis. We have postulated that the peritoneal iron overload originated from retrograde menstruation or bleeding lesions in the ectopic endometrium, which may contribute to the development of endometriosis by a wide range of mechanisms, including oxidative damage and chronic inflammation. Excessive NO production may also be associated with impaired clearance of endometrial cells by macrophages, which promotes cell growth in the peritoneal cavity. Therefore, further research of the mechanisms and consequences of macrophage apoptosis in endometriosis helps discover novel therapeutic strategies that are designed to prevent progression of endometriosis.

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Report of the Fifth Brazilian Symposium on HIV/AIDS Research

Cited by 3 publications

References 0 publications

Retention in Medical Care and Antiretroviral Treatment according to Skin Color in Southern Brazil

Retention in Medical Care and Antiretroviral Treatment according to Skin Color in Southern Brazil

A randomized controlled trial of a protocol of interviews designed to improve adherence to antiretroviral medications in southern Brazil

Role of iron overload-induced macrophage apoptosis in the pathogenesis of peritoneal endometriosis

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