Experimental kinetics of infection induced by Yersinia pseudotuberculosis isolated from stock animals

Martins, Carlos Henrique Gomes; Falcão, Deise Pasetto

doi:10.1590/s0074-02762004000600015

Cited by 4 publications

(4 citation statements)

References 24 publications

(22 reference statements)

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“…In a previous in vivo infection kinetics study, these two samples exhibited higher pathogenicity since they were more virulent and invasive than biotype 2 and serogroup O:3 strains (Martins & Falcão 2004). Fukushima et al (2001), studying 2235 Y. pseudotuberculosis strains of various bioserotypes and origins isolated from different regions of the planet, showed that all strains of the O:1a serotype exhibited a complete HPI.…”

Section: Discussionmentioning

confidence: 84%

Ribotyping and virulence markers of Yersinia pseudotuberculosis strains isolated from animals in Brazil

Martins

Bauab

Leite

et al. 2007

Mem. Inst. Oswaldo Cruz

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Section: Discussionmentioning

confidence: 84%

Ribotyping and virulence markers of Yersinia pseudotuberculosis strains isolated from animals in Brazil

Martins

Bauab

Leite

et al. 2007

Mem. Inst. Oswaldo Cruz

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“…The results presen-ted in this study show the ability of the micro-organisms to invade and multiply in the infected animals. This is directly related to the presence of the pYV plasmid regardless of the inoculation route as previously documented by Martins and Facao (2004). The ability of Y. pseudotuberculosis to neutralize the effects of the host's immune system and thus survive and spread through the spleen and liver depends on whether it harbors this plasmid.…”

Section: Resultsmentioning

confidence: 58%

“…Y. pseudotuberculosis causes various clinical syndromes in human and animals. To induce disease, a set of virulence factors related to plasmid and chromosomal genes must be present which contribute to host colonization and prevent the action of specific and non specific host defense mechanisms (Martins and Facao, 2004).…”

Section: Introductionmentioning

confidence: 99%

Experimental Yersinia pseudotuberculosis enteritis in laboratory animals

Okwori¹,

Agina²,

Odugbo³

et al. 2007

Afr. J. Biotechnol.

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The course of in vivo pathogenicity of Yersinia pseudotuberculosis in groups of rabbits and gunnea pigs were examined. One group of the animals was infected orally with 10 8 cfu/ml of test organism and the second group with standard reference strains. The third group was dosed with clean water as negative control. Both controls and Y. pseudotuberculosis infected animals were closely monitored for clinical signs for three weeks during which loss of body weight, rise in temperature, ruffling of fur were noticed. Pure isolates of the organisms were re-isolated from the faecal samples of the infected rabbits and guinea pigs. Animals orally fed with clean water showed no symptoms of yersiniosis. Rabbits infected with Y. pseudotuberculosis showed signs of illness while guinea pigs did not show any clinical sign. Visceral organs of infected rabbits showed enteritis with necrotic lesions but no pathological changes were observed in all guinea pigs including the controls. In the clinically ill animals, tissues analyzed demonstrated polarized profile and inflammatory cell influx throughout the course of the test. These findings should assist the Veterinary Pathologist recognize suspected cases of enteritis due to Y. psuedotuberculosis in the field among similar animal species.

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“…Moreover, there were good correlations between the ERIC-PCR, PFGE, and MLST clusters and the pathogenic potential of the strains tested. According to Martins and Falcão (2004) and Martins et al (2007), the Y. pseudotuberculosis strains belonging to the 1/O:1a bio-serogroup (clustered in the ST 42, ERIC-A, and PFGE-A profiles) harbor more virulence genes and are more invasive than the Y. pseudotuberculosis strains belonging to the 2/O:3 bio-serogroup (clustered in the ST 19, ERIC-B, and PFGE-B profiles). These authors searched for the presence of virulence genes and investigated the kinetics of infection in mice for a set of 68 Y. pseudotuberculosis strains isolated in Brazil, from which we selected the 40 strains that were studied in this research.…”

Section: Resultsmentioning

confidence: 99%

Molecular typing of Yersinia pseudotuberculosis strains isolated from livestock in Brazil

Souza

Imori

Passaglia³

et al. 2013

Genet. Mol. Res.

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ABSTRACT. Yersinia pseudotuberculosis can infect a broad range of animals. In Brazil, this bacterium has been isolated from healthy and sick animals from sporadic cases and outbreaks of hemorrhagic gastroenteritis among livestock. However, the molecular diversity of these isolates is little understood. In this study, we used multilocus sequence typing, enterobacterial repetitive intergenic consensus PCR and pulsed-field gel electrophoresis to genotype 40 Y. pseudotuberculosis strains belonging to bio-serogroups 1/O:1a and 2/O:3 isolated between 1982 and 1990 in the southern region of Brazil. All three methodologies clustered the strains into two main clusters according to their bioserogroups. Good correlations were observed between the clusters and the pathogenic potential of the strains. No correlation among the strains was observed according to geographical origin, host, place, or year of isolation. The grouping of the Y. pseudotuberculosis isolated in Brazil determined by these assays leads us to suggest that Brazilian livestock

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Experimental kinetics of infection induced by Yersinia pseudotuberculosis isolated from stock animals

Abstract: The course of in vivo infection of five isolates of

Cited by 4 publications

References 24 publications

Ribotyping and virulence markers of Yersinia pseudotuberculosis strains isolated from animals in Brazil

Ribotyping and virulence markers of Yersinia pseudotuberculosis strains isolated from animals in Brazil

Experimental Yersinia pseudotuberculosis enteritis in laboratory animals

Molecular typing of Yersinia pseudotuberculosis strains isolated from livestock in Brazil

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