Human toxocariasis: a seroepidemiological survey in schoolchildren of Sorocaba, Brazil

Coelho, Lina M P S; Silva, Marcos; Dini, Carlos Yoshizaki; Neto, Alcides A Giacon; Novo, Neil Ferreira; Silveira, Edilene P. R.

doi:10.1590/s0074-02762004000600002

Cited by 24 publications

(18 citation statements)

References 17 publications

(18 reference statements)

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“…A geofagia não mostrou significância estatística para alguns autores 16,[19][20][21] . Alguns estudos relatam presença de pica (ingestão de substâncias não comestíveis) nas crianças com LMV 1,3,[22][23][24][25][26][27][28] ; outros relatam a associação entre pica e toxocaríase 5,[29][30][31][32] .…”

Section: Epidemiologiaunclassified

“…O fato de possuir cão na casa foi um fator de risco para sorologia positiva em vários estudos 17,19,20,23,24,30,31,[34][35][36] . Alguns autores não encontraram associação entre os donos de cães 17 e a frequência de infecção por Toxocara, o que poderia ser explicado pelas medidas de higiene adequadas adotadas pelos adultos.…”

Section: Epidemiologiaunclassified

“…Em Brasília (DF), foi encontrada soropositividade para T. canis de 21,8% em amostras colhidas em laboratório de hospital público e de 3% em crianças de classe média, atendidas em laboratório privado 44 . Alguns estudos mostraram associação entre morar em zona rural e toxocaríase 17,20,35,45 .…”

Section: Epidemiologiaunclassified

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Toxocariasis: visceral larva migrans in children

Carvalho¹,

Rocha²

2011

J Pediatr (Rio J)

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Objectives: To present a detailed investigation of risk factors, symptoms, and laboratory and imaging tests that may be useful to establish the clinical laboratory diagnosis of visceral larva migrans (VLM) in children, demonstrating the importance of diagnosis and treatment to prevent complications in the eyes, liver, and other organs. Sources:Literature review using the MEDLINE and LILACS (1952-2009) databases, selecting the most recent and representative articles on the topic. Summary of the findings:VLM is an infectious disease with nonspecific clinical presentation, whose transmission is related to contact with dogs, especially puppies, and which may progress to late systemic complications in vital organs such as the eyes and the central nervous system. IgG (ELISA) anti-T. canis can be used to establish the laboratory diagnosis. Higher cutoff points suggest recent illness and lower cutoff points demonstrate mild infection or infection in remission. Therapeutic response may be assessed by means of eosinophil blood cell count. The present article provides the pediatrician with updated information regarding VLM, a disease of high prevalence worldwide and in Brazil. Conclusions:The diagnosis of VLM depends mainly on the presence of dogs in the child's household, associated with ELISA (IgG anti-T. canis), using excretory-secretory antigens of Toxocara canis. Prospective studies are warranted to assess the best drug therapy. Prevention is the most important strategy because of the high prevalence of T. canis in urban areas.J Pediatr (Rio J). 2011;87(2):100-110: Toxocara canis, dogs, infection, epidemiology, ELISA, prevalence. ResumoObjetivos: Apresentar investigação detalhada de fatores de risco, sintomatologia, exames laboratoriais e de imagem que possam contribuir para o diagnóstico clínico-laboratorial da larva migrans visceral (LMV) em crianças e mostrar a importância do diagnóstico e do tratamento para evitar complicações oculares, hepáticas e em outros órgãos. Fontes dos dados:Revisão de literatura utilizando os bancos de dados MEDLINE e LILACS , selecionando os artigos mais atuais e representativos do tema. Síntese dos dados:LMV é uma doença infecciosa de apresentação clínica inespecífica cuja transmissão está relacionada ao contato com cães, principalmente filhotes, podendo evoluir com complicações sistêmicas tardias em órgãos vitais como o olho e sistema nervoso central. Para diagnóstico laboratorial, pode ser utilizado IgG (ELISA) anti-Toxocara canis, cujos pontos de corte mais elevados sugerem doença recente e, os mais baixos, infecção leve ou em resolução. A resposta terapêutica pode ser avaliada por meio da contagem de eosinófilos no sangue. Esse artigo atualiza o pediatra em relação à LMV, doença de alta prevalência no mundo e no Brasil.Conclusões: O diagnóstico de LMV depende principalmente da epidemiologia da presença de cães no domicílio da criança, associada ao ELISA (IgG para T. canis), utilizando antígenos Toxocara de excreção e secreção. São necessários estudos prospectivos para avali...

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Section: Epidemiologiaunclassified

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Toxocariasis: visceral larva migrans in children

Carvalho¹,

Rocha²

2011

J Pediatr (Rio J)

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“…Authors detected anti-toxocara antibodies positive among schoolchildren living in a house with a yard and/or unpaved street and there was also an association between a seronegative ELISA test and previous treatment of pet dogs and/or cats with vermifuge [148]. The occurrence of cutaneous leishmaniasis in children living in N and NE Region, suggested transmission in and around the house, and in a few cases, children were entering the forest [143] or presence of a family member with a history of these disease [146].…”

Section: Children's Environment In Brazil: From Domestic (Indoor) To mentioning

confidence: 99%

“…According to literature, seroepidemiological surveys are an important research tool, especially in Public Health, because they allow the determination of the infection coefficient for a given pathology in a given population [148]. In that sense, the subtheme "exposure to other biological agents" showed us the importance of epidemiological studies present in endemic regions in Brazil, where the socioeconomic conditions are worse, or by children activities in the forest around the houses.…”

Section: Social -Sanitation and Socio-environmental Factorsmentioning

confidence: 99%

Children's Environment in Brazil: From Domestic (Indoor) to Regional Threats

Perlroth¹,

Branco²

2017

IJPCC

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Toxocariasis in the Americas: Burden and Disease Control

et al. 2014

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Human toxocariasis is a zoonotic parasitic disease that represents extensive morbidity in many countries. Caused by Toxocara canis and Toxocara cati, the clinical spectrum of this helminthiasis can be extended from asymptomatic forms up to life-threatening syndromes, such as the visceral larva migrans. Its epidemiology and burden is not clear; many times it is not diagnosed and, in most countries, it is not a notifiable disease. Some recent reviews have shown a large range of variability in terms of reported seroprevalence by countries. In this review, we summarized information regarding human toxocariasis burden of disease and control efforts in the region of the Americas.

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Human toxocariasis: a seroepidemiological survey in schoolchildren of Sorocaba, Brazil

Cited by 24 publications

References 17 publications

Toxocariasis: visceral larva migrans in children

Toxocariasis: visceral larva migrans in children

Children's Environment in Brazil: From Domestic (Indoor) to Regional Threats

Toxocariasis in the Americas: Burden and Disease Control

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