A comparative study of congenital toxoplasmosis between public and private hospitals from Uberlândia, MG, Brazil

Segundo, Gesmar Rodrigues Silva; Silva, Deise Aparecida Oliveira; Mineo, José Roberto; Ferreira, Marcelo Simão

doi:10.1590/s0074-02762004000100002

Cited by 23 publications

(14 citation statements)

References 25 publications

(35 reference statements)

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“…The infection rate observed in the present study is similar to those in other regions of the country, which ranged between 0.6 and 0.8%, even when different study methods are used. 11,16 Prospective studies by Spalding et al 18 (2003) and Varella et al 1 (2003) in the state of Rio Grande do Sul have reported even higher rates. According to Avelino et al 1 (2003), pregnant women are twice as likely to show seroconversion as are non-pregnant women, and seven times more likely if they are adolescents living in environments contaminated by the feces of host animals.…”

Section: Discussionmentioning

confidence: 95%

“…Some studies 12,16,22 have indicated that therapy can reduce fetal infection in 35 to 60% of cases. Despite the large number of studies over the last three decades, it is still not known whether prenatal treatment of women with presumed toxoplasmosis reduces congenital transmission of T.…”

Section: Discussionmentioning

confidence: 99%

“…The performance of programs for control of congenital toxoplasmosis in different regions of the country must be assessed. 17 In the state of Paraná, Southern Brazil, IgG anti-T. gondii prevalence ranged from 40% 4 to 66% 5 in 1983 e 1996 respectively, and 1.8% IgM anti-T. gondii seroincidence in pregnant women has been observed in northern areas of the state. 13 Based on routine laboratory tests during prenatal care, the objective of the present study was to verify the prevalence of suspected reagent serology for acute toxoplasmosis among pregnant women, and to describe the clinical, laboratory and therapeutic profiles of mothers and children suspected to have been exposed during gestation.…”

Section: Introductionmentioning

confidence: 99%

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Suspected acute toxoplasmosis in pregnant women

2007

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OBJECTIVE:To determine the prevalence of reagent serology for suspected acute toxoplasmosis in pregnant women and to describe clinical, laboratory and therapeutic profiles of mothers and their children. METHODS:A retrospective study was conducted with IgM-anti-Toxoplasma gondiireagent pregnant women and their children who attended the public health system in the state of Paraná, Southern Brazil, from January 2001 to December 2003. Information were obtained from clinical, laboratory (ELISA IgM/IgG) and ultrasonographic data and from interviews with the mothers. To test the homogeneity of the IgM indices in relation to the treatment used, the Pearson's Chi-square test was applied. Comparisons were considered significant at a 5% level. RESULTS:Two hundred and ninety (1.0%) cases of suspected IgM-reagent infection were documented, with a prevalence of 10.7 IgM-reagent women per 1,000 births. Prenatal care started within the first 12 weeks for 214/290; 146/204 were asymptomatic. Frequent complaints included headaches, visual disturbance and myalgia. Ultrasonography revealed abnormalities in 13 of 204 pregnancies. Chemoprophylaxis was administered to 112/227; a single ELISA test supported most decisions to begin treatment. Pregnant women with IgM indices =2.000 tended to be treated more often. Among exposed children, 44/208 were serologically followed up and all were IgGreagent, and three IgM-reagent cases showed clinical symptoms. CONCLUSIONS:The existence of pregnant women with laboratorially suspected acute toxoplasmosis who were not properly followed up, and of fetuses that were not adequately monitored, shows that basic aspects of the prenatal care are not being systematically observed. There is need of implementing a surveillance system of pregnant women and their children exposed to T. gondii. CONCLUSÕES: A existência de gestantes com suspeita laboratorial de toxoplasmose aguda não devidamente investigada e de conceptos sem monitoração adequada evidenciam que aspectos fundamentais da assistência pré-natal não estão sendo sistematicamente observados. Aponta-se a necessidade de implementar o sistema de vigilância para gestantes e crianças expostas ao T. gondii.28 Rev Saúde Pública 2007;41(1):27-34 Suspected acute toxoplasmosis in pregnancy Castilho-Pelloso MP et al Para testar a homogeneidade dos indices de IgM em relação ao tratamento usado, aplicou

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Section: Discussionmentioning

confidence: 95%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Suspected acute toxoplasmosis in pregnant women

2007

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“…Some congenital toxoplasmosis studies showed significant differences between the rate of positive diagnosis and the socioeconomic status of some Brazilian regions 14,15 . In addition, it has been observed that some eating habits increase the rate of Toxoplasma gondii transmission.…”

Section: Article/artigomentioning

confidence: 99%

Epidemiologic aspects of toxoplasmosis and evaluation of its seroprevalence in pregnant women

Fonseca

Silva

Fux

et al. 2012

Rev. Soc. Bras. Med. Trop.

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answered a quantitative questionnaire; 49.5% were seropositive for immunoglobulin (Ig) G and 3.6% for IgM. Comparative analysis of congenital toxoplasmosis cases were evaluated in 11 regions and showed an irregular distribution (p < 0.01). This difference was also observed among the pregnant women observed in each location. The results from the questionnaire show that 93% of the pregnant women had no knowledge about toxoplasmosis, and 24% presented with positive serology, but no clinical manifestation. Analysis for pregnant IgG-positive women and the presence of pets showed a statistically significant correlation (p < 0.05), suggesting that the transmission of this disease might occur in the domestic environment. Conclusions: We suggest the implementation of a triage program for pregnant women and health education to encourage their use of SUS services.

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“…As taxas de transmissão congênita e as manifestações clínicas variam de forma acentuada entre os indivíduos com infecção por T. gondii 7 . Neste trabalho evidenciou-se a necessidade de investimento em melhoria de técnicas laboratoriais, a fim de otimizar a assistência às gestantes e filhos expostos, uma vez que a indicação terapêutica pode ser onerosa ao serviço, apesar de saber-se que a utilização de quimioprofilático pode reduzir a transmissão ou as seqüelas ao feto 6 . Há necessidade também de intervir na qualidade das informações obtidas bem como sistematizá-las no sentido de facilitar a tomada de decisões.…”

Section: Comunicação/communicationunclassified

Monitoramento de gestantes com toxoplasmose em serviços públicos de saúde

Castilho-Pelloso

Falavigna

Araújo

et al. 2005

Rev. Soc. Bras. Med. Trop.

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RESUMOÉ discutido o monitoramento de 290 gestantes com suspeita de toxoplasmose aguda atendidas em serviços públicos. Em 69% um único teste (ELISA-IgM) conduziu ao tratamento. De 112 tratadas, o sistema não disponibilizou medicamento para 24%. Em 12,1% houve aumento progressivo de IgM e IgG. Em 48,2%, o tratamento foi iniciado trinta dias após o diagnóstico laboratorial. Palavras-chaves: Gestantes. Toxoplasmose. Pré-natal. Monitoramento. ABSTRACTThe monitoring of 290 pregnant women with suspicion of acute toxoplasmosis attended by Public Health Services is discussed. In 69% a single test (ELISA-IgM) led to the treatment. Of 112 treated, the system did not offer any drug to 24%. In 12.1% there was a progressive increase of IgM and IgG. In 48.2% the treatment was begun thirty days after the laboratorial diagnosis.

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A comparative study of congenital toxoplasmosis between public and private hospitals from Uberlândia, MG, Brazil

Abstract: The main purpose of the present study was to examine if there is difference in terms of incidence rates of congenital

Cited by 23 publications

References 25 publications

Suspected acute toxoplasmosis in pregnant women

Suspected acute toxoplasmosis in pregnant women

Epidemiologic aspects of toxoplasmosis and evaluation of its seroprevalence in pregnant women

Monitoramento de gestantes com toxoplasmose em serviços públicos de saúde

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