Humoral immune responses induced by Kudoa sp. (Myxosporea: Multivalvulida) antigens in BALB/c mice

Velasco, Gonzalo Martínez de; Rodero, M.; Zapatero, L.; Cuéllar, C.

doi:10.1590/s0074-02762002000800004

Cited by 11 publications

(15 citation statements)

References 11 publications

(14 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…On the other hand, the experiments carried out on the possible existence of cross-reactions between the Kudoa sp. antigens and the skeletal musculature of the Chilean hake revealed that the parasite did not share any antigens with M. gayi gayi (Martínez de Velasco et al 2002). The inexistence of common antigenic community between these parasites and their hosts capable of provoke allergenic reactions was confirmed in these patients because none of them was positive against white and blue fish extracts.…”

Section: Discussionmentioning

confidence: 84%

“…Previously, we had observed the presence of crossreactions between sera of animals immunised with "white" Kudoa extract and tested against "black" Kudoa extract and vice versa (Martínez de Velasco et al 2002). The recognition of both "black" and "white" Kudoa extracts by MIVM and FPS patients demonstrated the presence of common allergenic proteins between both antigens.…”

Section: Discussionmentioning

confidence: 85%

“…The elevated IgE responses obtained in all the immunised mice confirms the possible allergenic nature of some of the components of these parasites. These components could be responsible for the type I hypersensitivity reactions after their ingestion (Martínez de Velasco et al 2002;Martínez de Velasco and Cuéllar 2003).…”

Section: Discussionmentioning

confidence: 99%

“…We have previously shown (Martínez de Velasco et al 2002;Martínez de Velasco and Cuéllar 2003) that BALB/c mice immunised with "white" and "black" Kudoa sp. pseudocyst soluble extracts or orally inoculated with "white" Kudoa sp.…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Skin prick test of Kudoa sp. antigens in patients with gastrointestinal and/or allergic symptoms related to fish ingestion

et al. 2008

View full text Add to dashboard Cite

A majority of Kudoa spp. infects the somatic muscle of fish establishing cysts. Previously, elevated humoral responses were detected in BALB/c mice immunised with Kudoa sp. pseudocyst extracts and in BALB/c mice orally inoculated with Kudoa sp. pseudocysts, as well as the presence of anti-Kudoa sp. antibodies in human sera by enzyme-linked immunosorbent assay. The objective of this work was to test Kudoa sp. pseudocyst extracts by the skin prick test. Fifteen patients with gastroallergic and/or allergic symptoms related to fish ingestion were examined. Kudoa sp. pseudocyst extracts were administered (1 mg/ml) on the volar forearm skin. Four of the 15 selected patients were positive to Kudoa sp. extracts. The saline solution negative control did not induce any reaction.

show abstract

Section: Discussionmentioning

confidence: 84%

Section: Discussionmentioning

confidence: 85%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Skin prick test of Kudoa sp. antigens in patients with gastrointestinal and/or allergic symptoms related to fish ingestion

et al. 2008

View full text Add to dashboard Cite

show abstract

“…We have previously shown (Martínez de Velasco et al 2002) that BALB/c mice immunised with 'white' and 'black' Kudoa sp. pseudocyst soluble extracts or orally administered with 'white' Kudoa sp.…”

Section: Introductionmentioning

confidence: 99%

Seroprevalence of anti-Kudoa sp. (Myxosporea: Multivalvulida) antibodies in a Spanish population

et al. 2006

View full text Add to dashboard Cite

A majority of Kudoa species infect the somatic muscle of fish establishing cysts. Because there is no effective method to detect infected fish without destroying them, these parasitised fish reach the consumer. The elevated humoral responses detected previously by us in BALB/c mice immunised with Kudoa sp. pseudocyst extracts and the high IgG1 and IgE levels induced by the oral administration of Kudoa pseudocysts to BALB/c mice showed the possible immunopathological effects in man from the ingestion of Kudoa-infected fish. In this work, we investigated the seroprevalence of anti-Kudoa sp. antibodies in a Spanish healthy population and the possible association between the manifestation of allergic reactions after fish consumption and the humoral responses to Kudoa sp. antigens. Specific anti-Kudoa sp. antibody levels in sera of patients diagnosed with several digestive pathologies were also determined, studying their possible association with the alteration of analytic parameters in these patients.

show abstract

Myxozoans Exploiting Homeotherms

Hallett

Bartholomew

Székely

2015

Myxozoan Evolution, Ecology and Development

View full text Add to dashboard Cite

Humoral immune responses induced by Kudoa sp. (Myxosporea: Multivalvulida) antigens in BALB/c mice

Cited by 11 publications

References 11 publications

Skin prick test of Kudoa sp. antigens in patients with gastrointestinal and/or allergic symptoms related to fish ingestion

Skin prick test of Kudoa sp. antigens in patients with gastrointestinal and/or allergic symptoms related to fish ingestion

Seroprevalence of anti-Kudoa sp. (Myxosporea: Multivalvulida) antibodies in a Spanish population

Myxozoans Exploiting Homeotherms

Contact Info

Product

Resources

About