Epidemiology and dinamics of the vectorial transmission of Chagas disease

Sherlock, Ítalo Rodrigues de Araújo

doi:10.1590/s0074-02761999000700075

Cited by 6 publications

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“…However, in the absence of triatomines, as observed in the present study, we should still consider the possibility of trypanosomatid transmission by rodents and other wild animals such as opossums, which get increasingly closer to the peridomicile and/or domicile in search for shelter and food, mainly due to ecologic disequilibrium (4,5,23,24). Thus, in the present study we observed that dogs from the urban zone had higher rates of infection than dogs from the rural zone, as determined by blood culture and PCR.…”

Section: The Frequency Of Trypanosomatids Infection Among the Dogs Pcmentioning

confidence: 80%

Trypanosomatids in dogs belonging to individuals with chronic Chagas disease living in Botucatu town and surrounding region, São Paulo State, Brazil

Lucheis¹,

Silva²,

Araújo³

et al. 2005

J. Venom. Anim. Toxins incl. Trop. Dis

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Among domestic animals, dogs are considered to be the major reservoirs of trypanosomatids and, due to their proximity to man, the presence of these parasites in dogs is an alert to actions aiming at triatomine control. Fifty dogs (26 males and 24 females), aged from 2 months to 15 years, belonging to 30 chronic Chagas' disease individuals from 15 different municipalities in the western region of São Paulo State, Brazil, were subjected to blood collection for the following tests: artificial xenodiagnosis, blood culture, and Polymerase Chain Reaction (PCR). Fortythree (86%) out of 50 dogs were positive to at least one of the tests performed; 34 (68%) were positive to xenodiagnosis, 30 (60%) to blood culture, and 25 (50%) to PCR for T. cruzi and/or T. rangeli. Although triatomines were not detected during the intra and peridomiciliary inspections in the dog owners' residences, the results obtained demonstrate that there is a transmission cycle whereby triatomine vector may be participating in the infection epidemiological chain.

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Section: The Frequency Of Trypanosomatids Infection Among the Dogs Pcmentioning

confidence: 80%

Trypanosomatids in dogs belonging to individuals with chronic Chagas disease living in Botucatu town and surrounding region, São Paulo State, Brazil

Lucheis¹,

Silva²,

Araújo³

et al. 2005

J. Venom. Anim. Toxins incl. Trop. Dis

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Nitroheterocyclic derivatives: privileged scaffold for drug development against Chagas disease

Scarim

Chin

2019

Med Chem Res

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Thiazole, thio and semicarbazone derivatives against tropical infective diseases: Chagas disease, human African trypanosomiasis (HAT), leishmaniasis, and malaria

Scarim

Jornada

Machado

et al. 2019

European Journal of Medicinal Chemistry

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Epidemiology and dinamics of the vectorial transmission of Chagas disease

Cited by 6 publications

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Trypanosomatids in dogs belonging to individuals with chronic Chagas disease living in Botucatu town and surrounding region, São Paulo State, Brazil

Trypanosomatids in dogs belonging to individuals with chronic Chagas disease living in Botucatu town and surrounding region, São Paulo State, Brazil

Nitroheterocyclic derivatives: privileged scaffold for drug development against Chagas disease

Thiazole, thio and semicarbazone derivatives against tropical infective diseases: Chagas disease, human African trypanosomiasis (HAT), leishmaniasis, and malaria

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Epidemiology and dinamics of the vectorial transmission of Chagas disease

Cited by 6 publications

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Trypanosomatids in dogs belonging to individuals with chronic Chagas disease living in Botucatu town and surrounding region, São Paulo State, Brazil

Trypanosomatids in dogs belonging to individuals with chronic Chagas disease living in Botucatu town and surrounding region, São Paulo State, Brazil

Nitroheterocyclic derivatives: privileged scaffold for drug development against Chagas disease

Thiazole, thio and semicarbazone derivatives against tropical infective diseases: Chagas disease, human African trypanosomiasis (HAT), leishmaniasis, and malaria

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Trypanosomatids in dogs belonging to individuals with chronic Chagas disease living in Botucatu town and surrounding region, São Paulo State, Brazil

Trypanosomatids in dogs belonging to individuals with chronic Chagas disease living in Botucatu town and surrounding region, São Paulo State, Brazil