Emerging Infectious Diseases 1997-1998: The Role of Molecular Epidemiology

Molecular epidemiology of methicillin resistant Staphylococcus aureus isolated from newborns in a hospital in Rio de Janeiro, Brazil

“…Epidemiological transmission studies of MRSA have been traditionally performed by phenotypic characterization , Na'Was et al1998, therefore, the increasing of the molecu-lar epidemiology studies revolutioned our understanding of diseases transmission and allowed to recognize and investigate outbreaks in ways never before possible (Ostroff 1999). The identification of several new clones and distribution of endemics and epidemics strains became feasable through the use of molecular tools as pulsed field gel electrophoresis (PFGE) and restriction fragment length polymorphism (RFLP) of chromossomal DNA associated with hybridization techniques (Kreiswirth et al 1993, Teixeira et al 1995,Tambic et al 1997.…”

Phylogenetic analysis of spring virema of carp virus reveals distinct subgroups with common origins for recent isolates in North America and the UK

“…Molecular epidemiology has become an important tool in disease surveillance and investigations of outbreaks, due to its ability to trace and identify possible infection sources (Ostroff 1999). The SVCV genome comprises 11019 nucleotides (nt) of negative sense single-stranded RNA that encodes 5 major proteins in the order 3'N (nucleoprotein) -P (phosphoprotein) -M (matrix) -G (glycoprotein) -L (polymerase) 5' (Bjorklund et al 1996, Hoffmann et al 2002.…”

Phylogenetic analysis of spring viraemia of carp virus isolated in Serbia

“…Shedding of SVCV by survivors is likely the primary transmission mechanism (Fijan, 1988). Due to its ability to track and identify possible sources of infection, molecular epidemiology has become an essential tool in disease surveillance and outbreak investigations (Ostroff, 1999). The G gene, which exhibits relatively high genetic diversity compared to other genes, is widely used to infer intraspecific phylogeography of viral species (Kuzmin et al, 2009).…”