Comparative Histopathology of Biomphalaria glabrata, B. tenagophila and B. straminea with Variable Degrees of Resistance to Schistosoma mansoni Miracidia

Souza, Cecília Pereira de; Borges, Claudia Maria da Cunha; Santana, Andrea Guimaraes; Andrade, Zilton de Araújo

doi:10.1590/s0074-02761997000400014

Cited by 19 publications

(14 citation statements)

References 11 publications

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“…The capacity of the inner defense system (IDS) of that host to destroy the parasite is one of the factors that may determinate Biomphalaria susceptibility to S. mansoni infection (Souza et al 1997, Martins-Souza et al 2003. The IDS of Biomphalaria remains not completely understood, but it is well known that it is composed of cellular elements named hemocytes, and soluble components that could directly affect the larvae and/or act on the recognition of the parasite and activation of hemocytes.…”

mentioning

confidence: 99%

Differential lectin labelling of circulating hemocytes from Biomphalaria glabrata and Biomphalaria tenagophila resistant or susceptible to Schistosoma mansoni infection

Martins-Souza¹,

Pereira²,

Filho

et al. 2006

Mem. Inst. Oswaldo Cruz

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confidence: 99%

Differential lectin labelling of circulating hemocytes from Biomphalaria glabrata and Biomphalaria tenagophila resistant or susceptible to Schistosoma mansoni infection

Martins-Souza¹,

Pereira²,

Filho

et al. 2006

Mem. Inst. Oswaldo Cruz

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“…SOUZA et al 15 studied B. straminea and B. tenagophila exposed to miracidia and could observe inflammatory diffused reactions with encapsulated sporocysts by amebocytes. This cellular reaction suggests a low susceptibility and a delay on the parasite development into the snail, which increases the prepatent period making the diagnosis through light exposure very difficult.…”

Section: Resultsmentioning

confidence: 99%

Susceptibility of Biomphalaria tenagophila and Biomphalaria straminea to Schistosoma mansoni infection detected by low stringency polymerase chain reaction

Jannotti-Passos

Souza

2000

Rev. Inst. Med. trop. S. Paulo

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SUMMARYIn order to determine Schistosoma mansoni infection rates in Biomphalaria tenagophila and B. straminea, low stringency polymerase chain reaction (LS-PCR) technique was used as a complementary method to light exposure technique. LS-PCR has already been standardized in our laboratory to detect the trematode DNA in B. glabrata. Higher S. mansoni infection rates were detected using conventional method and LS-PCR. The parasite DNA profile was detected in both species after 7-day exposure to miracidia, using LS-PCR. This technique enables early detection of schistosomiasis transmission focuses, in endemic areas, before the beginning of cercariae shedding.

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“…1 Differences in susceptibility of these snail species are strongly related to the capacity of their defense system to encapsulate and destroy the parasites. [2][3][4][5] Even though B. straminea and B. tenagophila are present in Argentina, there are no reports on the presence of S. mansoni in this country so far. 6 In our laboratory, we maintain a colony of B. straminea from the locality of San Miguel, Corrientes province, Argentina.…”

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confidence: 98%

Short report: Schistosoma mansoni miracidia are killed by the defense system of an Argentine strain of Biomphalaria straminea.

Grassi¹,

Jordá²,

Andrade³

et al. 2001

The American Journal of Tropical Medicine and Hygiene

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Abstract. Biomphalaria straminea snails from Argentina fail to shed cercariae even if exposed to high doses of Schistosoma mansoni EC miracidia. Alternative explanations for this failure are that miracidia are unable to penetrate the snail's epithelium or that the miracidia are killed by the snail's defense system. To discriminate between these 2 possibilities, B. straminea snails were individually exposed to increasing doses of miracidia. Susceptible B. glabrata were used as controls. Exposed snails were fixed 12 hr after exposure, and histological sections of the whole specimens were examined. Miracidia were seen to penetrate the epithelium of B. straminea and B. glabrata at similar rates (14.7%), independent of the exposure level. Regardless of the miracidial dose, 94% of the penetrating miracidia appeared encapsulated by the B. straminea defense system, whereas in B. glabrata, only 42% of the miracidia underwent encapsulation. These results show that resistance of B. straminea to S. mansoni EC strain is due to an efficient defense system that destroys miracidia once they have penetrated.

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Comparative Histopathology of Biomphalaria glabrata, B. tenagophila and B. straminea with Variable Degrees of Resistance to Schistosoma mansoni Miracidia

Cited by 19 publications

References 11 publications

Differential lectin labelling of circulating hemocytes from Biomphalaria glabrata and Biomphalaria tenagophila resistant or susceptible to Schistosoma mansoni infection

Differential lectin labelling of circulating hemocytes from Biomphalaria glabrata and Biomphalaria tenagophila resistant or susceptible to Schistosoma mansoni infection

Susceptibility of Biomphalaria tenagophila and Biomphalaria straminea to Schistosoma mansoni infection detected by low stringency polymerase chain reaction

Short report: Schistosoma mansoni miracidia are killed by the defense system of an Argentine strain of Biomphalaria straminea.

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