Blastocystis hominis Infection in Cuban AIDS Patients

Escobedo, Ángel A.; Núñez, Fidel A.

doi:10.1590/s0074-02761997000300003

Cited by 8 publications

(3 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This was in agreement with the findings obtained by Escobedo and Nunez [14]. It has been reported that patients with suppressed immunity and positive for B. hominis infection were presented with diarrhea and other gastrointestinal symptoms [8,15].…”

Section: Discussionsupporting

confidence: 92%

Opportunistic Parasites among Immunosuppressed Children in Minia District, Egypt

et al. 2012

View full text Add to dashboard Cite

A total of 450 stool samples were collected from inpatient and outpatient clinics of Pediatric Department, Minia University Hospital, Minia District, Egypt. Two groups of patients were studied, including 200 immunosuppressed and 250 immunocompetent children. Stool samples were subjected to wet saline and iodine mounts. A concentration technique (formol-ether sedimentation method) was carried out for stool samples diagnosed negative by wet saline and iodine mounts. Samples were stained by 2 different methods; acid fast stain (modified Ziehl-Neelsen stain) and Giemsa stain. Total 188 cases (94%) were diagnosed positive for parasitic infections among immunosuppressed children, whereas 150 cases (60%) were positive in immunocompetent children (P<0.0001). The most common protozoan infection in immunosuppressed group was Cryptosporidium parvum (60.2%), followed by Blastocystis hominis (12.1%), Isospora belli (9.7%), and Cyclospora caytenensis (7.8%). On the other hand, Entamoeba histolytica (24.6%) and Giardia lamblia (17.6%) were more common than other protozoans in immunocompetent children.

show abstract

Section: Discussionsupporting

confidence: 92%

Opportunistic Parasites among Immunosuppressed Children in Minia District, Egypt

et al. 2012

View full text Add to dashboard Cite

show abstract

“…A consistent association between HIV infection and intestinal parasitosis has been reported in tropical regions [ 1 ] and more so in patients with CD4 + T-cell counts less than 200 cells/mm 3 [ 2 ]. Data on correlation of HIV/AIDS with enteric parasitic infection in South Asian region have reported association of several species of pathogenic protozoa such as Cryptosporidium spp., Cystoisospora belli, Cyclospora cayetanensis, Giardia lamblia, Entamoeba histolytica, Blastocystis hominis , and microsporidia species [ 3 ]. The clinical spectrum caused by intestinal parasites among HIV positive patients ranges from asymptomatic to severe infections leading to chronic diarrhea, dehydration, and malabsorption [ 4 ].…”

Section: Introductionmentioning

confidence: 99%

Intestinal Parasitosis in Relation to Anti-Retroviral Therapy, CD4+ T-cell Count and Diarrhea in HIV Patients

et al. 2015

View full text Add to dashboard Cite

Intestinal parasitic infections are one of the major causes of diarrhea in human immunodeficiency virus (HIV) seropositive individuals. Antiretroviral therapy has markedly reduced the incidence of many opportunistic infections, but parasite-related diarrhea still remains frequent and often underestimated especially in developing countries. The present hospital-based study was conducted to determine the spectrum of intestinal parasitosis in adult HIV/AIDS (acquired immunodeficiency syndrome) patients with or without diarrhea with the levels of CD4+ T-cell counts. A total of 400 individuals were enrolled and were screened for intestinal parasitosis. Of these study population, 200 were HIV seropositives, and the remaining 200 were HIV uninfected individuals with or without diarrhea. Intestinal parasites were identified by using microscopy as well as PCR assay. A total of 130 (32.5%) out of 400 patients were positive for any kinds of intestinal parasites. The cumulative number of parasite positive patients was 152 due to multiple infections. A significant association of Cryptosporidium (P<0.001) was detected among individuals with CD4+ T-cell counts less than 200 cells/μl.

show abstract

“…The problem of B. hominis infection in AIDS patients has been reported (11,12,13,14,15). Garavelli et.al., (13) indicated that patients with full-blown AIDS and who test positive for Blastocystis hominis presented with diarrhoea, nausea, flatulence, tenesmus, itching, abdominal pain and peripheral blood eosinophilia.…”

Section: Introductionmentioning

confidence: 99%

Significance of <i>Blastocystis hominis </i> in patients referred for bacteriological stool culture at EHNRI

Endeshaw¹,

Tadesse²,

Petros³

2007

Ethiopian Journal of Health Development

View full text Add to dashboard Cite

Background: The pathogenic potential of the parasite Blastocystis hominis is often considered controversial. However, it is now gaining acceptance as a human intestinal parasitic agent showing different clinical symptoms. Objective: To determine the prevalence and related clinical manifestation of B. hominis infection in patients referred for bacteriological stool culture at the Ethiopian Health & Nutrition Research Institute (EHNRI). Methods: A total of 152 patients referred for bacteriological stool culture to the bacteriology and parasitology labs at EHNRI, were examined for possible infection with B. hominis. A single stool sample from each individual was collected and processed for isolation of bacteria by using a standard culture method for enteric bacteria, while direct and formol-ether concentration methods were used for the detection of ova and parasites; and the Modified Ziehl Neelsen method was applied for Cryptosporidium parvum and Isospora belli and water-ether sedimentation with Uvitex-2B staining method was used for detecting intestinal microsporidia. Clinical information was recorded during stool sample collection. Results: One Salmonella spp., two Shigella spp. and one case of Escherichia coli were isolated. Blastocystis hominis was detected in 71(46.7%) of the 152 patients examined and 51/71(71.8%) of the patients were found to have been infected with B. hominis alone. Well known opportunistic intestinal parasites-Cryptosporidium parvum 11(7.2%), Isospora belli 13 (8.6%) and Enterocytozoon bieneusi 2 (1.3 %)-were also recorded. Among the helminths, Strongyloides stercoralis 5 (3.3 %) was identified to be the most prevalent. The most common clinical symptoms significantly associated with B. hominis were distension, flatulence and anorexia (P<0.05). Among the positive cases, four staff members (three males aged 38, 40 and 45 years old and one female aged 42 years old) who were infected with B. hominis alone were treated with metronidazole 250 mg, 2 tablets three times a day for 10 days, and responded favourably and all clinical symptoms resolved. Conclusions: This information is expected to strengthen the newly emerging perception on the pathogenic potential of B. hominis infection. It will also create an awareness of laboratory technicians and physicians for proper diagnosis and management of the disease. From this and other related studies conducted elsewhere, it could be concluded that treating B. hominis infections where defined symptoms are presented with large numbers of parasites in the stool and in the absence of other cases of the disease is recommendable.

show abstract

Blastocystis hominis Infection in Cuban AIDS Patients

Cited by 8 publications

References 0 publications

Opportunistic Parasites among Immunosuppressed Children in Minia District, Egypt

Opportunistic Parasites among Immunosuppressed Children in Minia District, Egypt

Intestinal Parasitosis in Relation to Anti-Retroviral Therapy, CD4+ T-cell Count and Diarrhea in HIV Patients

Significance of <i>Blastocystis hominis </i> in patients referred for bacteriological stool culture at EHNRI

Contact Info

Product

Resources

About