The intermediate snail-host: an agenda for future study

Michelson, Edward H.

doi:10.1590/s0074-02761987000800033

Cited by 5 publications

(3 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…18,19 Snails of the Biomphalaria genus are the preferential intermediate host in the asexual cycle. 13,20,21 Schistosoma japonicum is endemic in China and Southeast Asia, where it uses snails in the Oncomelania genus as its intermediate host, ultimately affecting the intestinal and hepatic circulatory system, preferentially the superior mesenteric veins. Schistosoma mekongi, found in Cambodia and Laos, affects both the superior and inferior mesenteric veins.…”

Section: Case Presentationmentioning

confidence: 99%

Schistosomiasis-Associated Pulmonary Hypertension

Graham

Bandeira

Morrell

et al. 2010

Chest

101

View full text Add to dashboard Cite

Inflammation is likely a critical underlying etiology in many forms of severe pulmonary hypertension (PH), and schistosomiasis-associated PH, one of the most common causes of PH worldwide, is likely driven by the host response to parasite antigens. More than 200 million people are infected with schistosomiasis, the third most common parasitic disease, and approximately 1% of those chronically infected develop PH. Acute cutaneous infection causes inflammation at the site of parasite penetration followed by a subacute immune complex-mediated hypersensitivity response as the parasite migrates through the lungs. Chronic schistosomiasis infection induces a granulomatous inflammation around ova deposited in the tissue. In particular, Schistosoma mansoni migrates to the portal venous system and causes preportal fibrosis in a subset of individuals and appears to be a prerequisite for PH. Portal hypertension facilitates shunting of ova from the portal system to the pulmonary arterial tree, resulting in localized periovular pulmonary granulomas. The pulmonary vascular remodeling is likely a direct consequence of the host inflammatory response, and portopulmonary hypertension may be a significant contributor. New specific therapies available for PH have not been widely tested in patients with schistosomiasis and often are unavailable for those infected in resource-poor areas of the world where schistosomiasis is endemic. Furthermore, the current PH therapies in general target vasodilation rather than vascular remodeling and inflammation. Further research is needed into the pathogenic mechanism by which this parasitic infection results in pulmonary vascular remodeling and PH, which also may be informative regarding the etiology of other types of PH.

show abstract

Section: Case Presentationmentioning

confidence: 99%

Schistosomiasis-Associated Pulmonary Hypertension

Graham

Bandeira

Morrell

et al. 2010

Chest

101

View full text Add to dashboard Cite

show abstract

“…Potentialities of the snail biological control have recently been emphasized by Michelson (1987) and Coimbra (1991). Attention should be particularly paid to the concept of snail control by genetic manipulation, first proposed 34 years ago by Hubendick (1958).…”

Section: Commentsmentioning

confidence: 99%

Long-term controlled field experiment on the competition between two species of Biomphalaria (Mollusca, Basommatophora), the snail vectors of Schistosoma mansoni in Northeastern Brazil

Barbosa

Arruda

1993

Cad. Saúde Pública

View full text Add to dashboard Cite

A long-term controlled field experiment on the interactions of the populations of Biomphalaria glabrata (target population) and B. straminea (competitor) was carried out in the county of Alhandra, state of Paraíba, Brazil, during the period 1980 through 1989. Results obtained in the current paper show that the snail B. straminea has strong competitive advantages over B. glabrata. In six out of nine streams the native population of B. glabrata were totally excluded and replaced by B. straminea. There is evidence showing that seasonal dryness has marked influence on the phenomenon studied in this paper. In all the streams were B. straminea already predominated, return of B. glabrata was never observed.

show abstract

“…O estabelecimento da esquistossomose em uma determinada região dependerá das espécies de planorbídeos existentes, do grau de saneamento básico, das condições climáticas que possibilitem a realização das diversas fases do ciclo larvário do parasito e do contato da população humana com os criadouros de moluscos (COELHO, 1959;MICHELSON, 1987).…”

unclassified

Aspectos ecológicos e levantamento malacológico para identificação de áreas de risco para transmissão da esquistossomose mansoni no litoral norte de Pernambuco, Brasil

Souza

Barbosa

Albuquerque

et al. 2010

Iheringia, Sér. Zool.

View full text Add to dashboard Cite

ABSTRACT. Ecological aspects and malacological survey to identification of transmission riskglabrata collected, 44 specimens were positive for Schistosoma mansoni Sambon, 1907 cercariae and 91 specimens were positive for other trematode larvae. One Pomacea sp. specimen was positive for trematode larvae. These data, spatially georeferenced, will be used for determination of risk' sites for schistosomiasis transmission at Carne de Vaca beach and furthermore, they will be used for computational simulations to determine the expansion process of schistosomiasis in state of Pernambuco.

show abstract

The intermediate snail-host: an agenda for future study

Cited by 5 publications

References 0 publications

Schistosomiasis-Associated Pulmonary Hypertension

Schistosomiasis-Associated Pulmonary Hypertension

Long-term controlled field experiment on the competition between two species of Biomphalaria (Mollusca, Basommatophora), the snail vectors of Schistosoma mansoni in Northeastern Brazil

Aspectos ecológicos e levantamento malacológico para identificação de áreas de risco para transmissão da esquistossomose mansoni no litoral norte de Pernambuco, Brasil

Contact Info

Product

Resources

About