Antigens of plasmodium vivax blood stage parasites identified by monoclonal antibodies

A 95 kDa protein of Plasmodium vivax and P. cynomolgi visualized by three‐dimensional tomography in the caveola–vesicle complexes (Schüffner's dots) of infected erythrocytes is a member of the PHIST family

“…This study is one of only a few since 1975 to investigate the structure and molecular make-up of Plasmodium CVCs (Aikawa et al , 1975; Barnwell et al , 1990; Barnwell, 1986; Aikawa et al , 1977; Atkinson et al , 1990; Bracho et al , 2006; Udagama et al , 1988; Matsumoto et al , 1988; Matsumoto et al , 1986) and the first to present these structures in 3-D. The ET imaging results presented here corroborate previous TEM reports showing numerous CVCs interspersed along the surface of the P. vivax and P. cynomolgi iRBCs with their caveolae open to the surface (Aikawa et al , 1975).…”

Detection of etiological agents of malaria in howler monkeys from Atlantic Forests, rescued in regions of São Paulo city, Brazil

“…These parasites naturally infect monkeys from the families Cebidae and Atelidae. P. simium and P. brasilianum are similar to human P. vivax and P. malariae , respectively, and these similarities occur at the morphological, genetic, and immunological level [3, 11–14, 20, 21, 24, 26, 27, 30, 34].…”

Widespread occurrence of antibodies against circumsporozoite protein and against blood forms of Plasmodium vivax, P. falciparum and P. malariae in Brazilian wild monkeys

“…Similarities in morphological and immunological responses between P. vivax and P. simium [3, 5, 10, 17, 27] and P. malariae and P. brasilianum were reported [5–7, 19]. Molecular and phylogeny studies based on 18S ribosomal subunit RNA (ssrRNA), the circumsporozoite protein (CSP) gene and cytochrome b gene of P. malariae / P. brasilianum [14, 15, 23], P. vivax / P. simium [14, 18] and human P. vivax ‐like/ P. simiovale [13] showed that they are not distinct and that P. falciparum / P. reichenowi (a parasite of Pan troglodytes , an Old World ape) are very closely related [13, 14, 21].…”