Velocidade da onda de pulso, pressão arterial e adipocitocinas em adultos jovens: estudo do Rio de Janeiro

Pizzi, Oswaldo Luiz; Brandão, Andréa Araújo; Pozzan, Roberto; Magalhães, Maria Eliane Campos; Campana, Érika Maria Gonçalves; Fonseca, Flavia Lopes; Freitas, Elizabete Viana de; Brandão, Ayrton Pires

doi:10.1590/s0066-782x2012005000116

Cited by 9 publications

(4 citation statements)

References 37 publications

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“…Most studies have demonstrated an association between increased PWV, age, and BP. 16 In this study, BP was controlled in the linear regression adjustment to assess PWV, and the age range studied was narrow (9-10 years). Thus, it did not affect the PWV result of in the studied population or the other findings.…”

Section: Discussionmentioning

confidence: 99%

“…A maioria dos estudos aponta associação entre aumento da VOP, idade e pressão arterial. 16 Nesta pesquisa, a pressão arterial foi controlada no ajuste da regressão linear para avaliar a VOP e a faixa etária estudada era estreita (nove a 10 anos), não representando um problema para o resultado da VOP na população estudada ou sobre os demais achados do estudo.…”

Section: Discussionunclassified

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Factors associated with arterial stiffness in children aged 9-10 years

et al. 2015

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OBJECTIVE To analyze the factors associated with stiffness of the great arteries in prepubertal children.METHODS This study with convenience sample of 231 schoolchildren aged 9-10 years enrolled in public and private schools in Vitória, ES, Southeastern Brazil, in 2010-2011. Anthropometric and hemodynamic data, blood pressure, and pulse wave velocity in the carotid-femoral segment were obtained. Data on current and previous health conditions were obtained by questionnaire and notes on the child’s health card. Multiple linear regression was applied to identify the partial and total contribution of the factors in determining the pulse wave velocity values.RESULTS Among the students, 50.2% were female and 55.4% were 10 years old. Among those classified in the last tertile of pulse wave velocity, 60.0% were overweight, with higher mean blood pressure, waist circumference, and waist-to-height ratio. Birth weight was not associated with pulse wave velocity. After multiple linear regression analysis, body mass index (BMI) and diastolic blood pressure remained in the model.CONCLUSIONS BMI was the most important factor in determining arterial stiffness in children aged 9-10 years.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionunclassified

Factors associated with arterial stiffness in children aged 9-10 years

et al. 2015

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“…In comparison, vascular health in younger adults has received more limited attention [ 14 ], despite evidence showing that arterial aging begins early in life [ 15 – 16 ] and that the negative consequences of arterial stiffness in relatively young populations are associated with poorer white matter health and reduced gray matter volume [ 17 ]. These adverse outcomes are also compounded by other known cardiovascular risk factors, such as low cardiorespiratory fitness (CRF) and poor dietary intake [ 18 – 20 ], emphasizing the need for control and intervention strategies at younger ages [ 21 – 22 ] for the prevention of age-related cognitive decline.…”

Section: Introductionmentioning

confidence: 99%

Mapping cerebral pulse pressure and arterial compliance over the adult lifespan with optical imaging

et al. 2017

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Cerebrovascular health is important for maintaining a high level of cognitive performance, not only in old age, but also throughout the lifespan. Recently, it was first demonstrated that diffuse optical imaging measures of pulse amplitude and arterial compliance can provide estimates of cerebral arterial health throughout the cortex, and were associated with age, estimated cardiorespiratory fitness (eCRF), neuroanatomy and cognitive function in older adults (aged 55–87). The current study replicates and extends the original findings using a broader age range (a new adult sample aged 18–75), longer recording periods (360 s), and a more extensive optical montage (1536 channels). These methodological improvements represent a 5-fold increase in recording time and a 4-fold increase in coverage compared to the initial study. Results show that reliability for both pulse amplitude and compliance measures across recording blocks was very high (r(45) = .99 and .75, respectively). Pulse amplitude and pulse pressure were shown to correlate with age across the broader age range. We also found correlations between arterial health and both cortical and subcortical gray matter volumes. Additionally, we replicated the correlations between arterial compliance and age, eCRF, global brain atrophy, and cognitive flexibility. New regional analyses revealed that higher performance on the operation span (OSPAN) working memory task was associated with greater localized arterial compliance in frontoparietal cortex, but not with global arterial compliance. Further, greater arterial compliance in frontoparietal regions was associated with younger age and higher eCRF. These associations were not present in the visual cortex. The current study not only replicates the initial one in a sample including a much wider age range, but also provides new evidence showing that frontoparietal regions may be especially vulnerable to vascular degeneration during brain aging, with potential functional consequences in cognition.

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“…However, a statement from the American Heart Association said that arterial stiffness represents a cause rather than a consequence of hypertension [ 15 ]. Monitoring BP may be useful for the identification of vascular impairment [ 36 ], and baPWV can be used to predict the progression of BP and incident hypertension and determine the individual response to antihypertensive treatment [ 37 – 40 ]. Whether baPWV could be a useful screening tool to identify apparently healthy subjects who should be targeted for inventions aimed at preventing incident hypertension requires further study.…”

Section: Discussionmentioning

confidence: 99%

Factors Associated with Brachial-Ankle Pulse Wave Velocity in an Apparently Healthy Chinese Population

Chen

Liu

Jia

et al. 2020

BioMed Research International

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Purpose. To investigate the factors influencing brachial-ankle pulse wave velocity (baPWV) in an apparently healthy Chinese population, especially the associations between baPWV and indices of blood pressure (BP). Methods. A total of 1123 participants with no history of hypertension were enrolled in this study, and the baPWV and BP of all four limbs were measured along with other covariates. Correlation analyses and multivariate linear regression models were used to identify factors associated with baPWV. Results. A total of 1123 participants (male 43.3%, mean age: 58.4±13.9 years) were included. The average baPWV was 14.87±3.21 m/s, and no difference was found between the sexes. Age was positively correlated with baPWV (r=0.65, p<0.01), especially in females (r=0.71 versus 0.56 in males). The correlation coefficient between age and baPWV increased markedly after the age of 65 years. In addition, the resting heart rate (RHR), waist-hip ratio, glomerular filtration rate, and plasma glucose level were significantly correlated with baPWV (r=0.25, 0.22, -0.43, and 0.25, respectively; p<0.01). BP parameters were highly positively correlated with baPWV, especially systolic BP (SBP) and pulse pressure (PP). Multivariate regression revealed that age, BP parameters, and RHR were independently correlated with baPWV (p<0.01) after adjusting for confounding factors. The standardized coefficients of SBP were greater than those of PP, followed by diastolic BP (DBP). Conclusion. BaPWV increased with age, especially after 65 years. Age, BP, and RHR were independent factors associated with baPWV. The effect of SBP on baPWV was more prominent than that of PP.

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Velocidade da onda de pulso, pressão arterial e adipocitocinas em adultos jovens: estudo do Rio de Janeiro

Abstract: Background: Data on noninvasive vascular assessment and their association with cardiovascular risk variables are scarce in young individuals.

Cited by 9 publications

References 37 publications

Factors associated with arterial stiffness in children aged 9-10 years

Factors associated with arterial stiffness in children aged 9-10 years

Mapping cerebral pulse pressure and arterial compliance over the adult lifespan with optical imaging

Factors Associated with Brachial-Ankle Pulse Wave Velocity in an Apparently Healthy Chinese Population

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