Dessincronia ventricular e aumento dos níveis de BNP na estimulação apical do ventrículo direito

Abreu, Claudia Drummond Guimarães; Nunes, Maria do Carmo Pereira; Barbosa, Márcia M.; Rocha, Manoel Otávio Costa; Ribeiro, Antônio Luiz Pinho

doi:10.1590/s0066-782x2011005000070

Cited by 4 publications

(1 citation statement)

References 18 publications

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“…This value correlates to mild ventricular dysfunction 34 . Abreu et al 35 showed that in patients with conventional pacing, intraventricular dyssynchrony was an independent predictor of increased BNP levels, after adjustment for age and ejection fraction. On the other hand, Nikoo et al 36 found no correlation between BNP levels and pacing site (apical versus non-apical).…”

Section: Discussionmentioning

confidence: 99%

Is Conventional Cardiac Pacing Harmful in Patients with Normal Ventricular Function?

Sá¹,

Rassi²,

Batista³

2013

Arquivos Brasileiros De Cardiologia

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BackgroundRight ventricular pacing may be deleterious in patients with left ventricular dysfunction, but in patients with normal function the impact of this stimulation triggering clinically relevant ventricular dysfunction is not fully established.ObjectivesTo evaluate the clinical, echocardiographic findings of patients with previously normal left ventricular function underwent implantation of a pacemaker.MethodsObservational, cross-sectional study with 20 patients, who underwent implantation of pacemaker, prospectively followed-up, with the following inclusion criteria: normal left ventricular function defined by echocardiography and ventricular pacing higher than 90%. Were evaluated functional class (FC) (New York Heart Association), 6-minute walk test (6MWT), B-type natriuretic peptide (BNP), echocardiographic assessment (conventional and dyssynchrony parameters), and quality of life questionnaire (QLQ) (SF-36). The assessment was performed at ten days (t1), four months (t2), eight months (t3), 12 months (t4) and 24 months (t5).ResultsConventional echocardiographic parameters and dyssynchrony parameters showed statistically significant variation over time. The 6MWT, FC, and BNP showed worsening at the end of two years. QLQ showed initial improvement and worsening at the end of two years.ConclusionThe implantation of conventional pacemaker was associated with worsening in functional class, worsening in walk test, increased BNP levels, increased duration of QRS, and worsening in some domains of the QLQ at the end of two years. There were no changes in echocardiography measurements (conventional and asynchrony measures).

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Section: Discussionmentioning

confidence: 99%

Is Conventional Cardiac Pacing Harmful in Patients with Normal Ventricular Function?

Sá¹,

Rassi²,

Batista³

2013

Arquivos Brasileiros De Cardiologia

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Comparison of early effects of right ventricular apical pacing on left ventricular functions in single and dual chamber pacemakers

Algazzar

Moharram

Katta

et al. 2015

The Egyptian Heart Journal

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Objectives: Our study aimed to demonstrate the early negative impact of right ventricular apical pacing induced by single (VVI) and dual chamber (DDD) pacemakers on LV functions in patients with preserved EF. And to assess that single brain natriuretic peptide (BNP) after 2 months of implantation is correlated to ventricular dyssynchrony. Methods: 40 patients with implanted VVI and DDD pacemakers were examined before implantation and again after 2 and 6 months of implantation for BNP, left ventricular (LV) systolic and diastolic functions by echocardiography and pulsed tissue Doppler. After 6 months, patients with DDD pacemakers were crossed over to VVI mode of pacing for 2 weeks with lower rate programed to 60 beat per minute then sample for BNP was collected again. Results: There was no statistically significant difference in LV systolic and diastolic functions except for myocardial performance index (MPI) with (P value of 0.03). Mean BNP level in VVI pacing was higher than DDD pacing after two months with P value = 0.001 while comparison after 6 months showed P value = 0.023. There was a statistically significant difference between both groups in results of aortic preejection delay (APED) (P value of <0.05). BNP was correlated to APED (r = 0.651 and P value = 0.001) and pacing percentage (r = 0.687 and P value = 0.00). Conclusion: Loss of atrioventricular synchrony in VVI mode leads to a significant difference in LV dyssynchrony between both groups. BNP level is correlated to LV dyssynchrony and pacing percentage. ª 2014 Production and hosting by Elsevier B.V. on behalf of Egyptian Society of Cardiology. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/3.0/).

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Effect of pacemaker site on B-type natriuretic peptide levels and left ventricular function in a population with high prevalence of Chagas disease

Souza

Nascimento

Nunes

et al. 2015

International Journal of Cardiology

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Dessincronia ventricular e aumento dos níveis de BNP na estimulação apical do ventrículo direito

Abstract: In clinically stable patients receiving conventional cardiac pacing, the intraventricular dyssynchrony was an independent predictor of BNP level increase after adjusted for age and LVEF.

Cited by 4 publications

References 18 publications

Is Conventional Cardiac Pacing Harmful in Patients with Normal Ventricular Function?

Is Conventional Cardiac Pacing Harmful in Patients with Normal Ventricular Function?

Comparison of early effects of right ventricular apical pacing on left ventricular functions in single and dual chamber pacemakers

Effect of pacemaker site on B-type natriuretic peptide levels and left ventricular function in a population with high prevalence of Chagas disease

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