Valvoplastia mitral percutânea: 30 anos de experiência

Wainstein, Marco Vugman; Wainstein, Rodrigo Vugman

doi:10.1590/s0066-782x2010000300002

Cited by 4 publications

(7 citation statements)

References 9 publications

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“…Furthermore, these medical conditions might negatively impact the course of the illness. For example, comorbid T2D is associated with an increased risk of recurrent episodes, frequent hospitalizations, suicidality, and poor response to conventional mood stabilizers in BD (Calkin et al, 2009, Gomes et al, 2010, Kim et al, 2009). Obesity appears to be a risk factor for relapse to depression as shown by the high number of obese patients experiencing a depressive recurrence (Fagiolini et al, 2003).…”

Section: Introductionmentioning

confidence: 99%

Lifestyle interventions targeting dietary habits and exercise in bipolar disorder: A systematic review

Bauer

Gálvez

Hamilton

et al. 2016

Journal of Psychiatric Research

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Background Bipolar disorder (BD) is a serious mental illness associated with a high risk of medical comorbidities, long-term disability and premature death. This systematic review examined the current literature on therapeutic interventions targeting nutrition and physical activity in BD and collecting health-related measures such as mood and course of illness. Methods Scopus (all databases), Pubmed and Ovid Medline were systematically searched with no language or year restrictions, up to June 2015, for studies focusing on lifestyle interventions in BD. Search terms were related to bipolar disorder, nutrition, physical activity, wellbeing, psychosocial interventions and course of illness. We hand searched content pages of Bipolar Disorders and Journal of Affective Disorders and checked references of relevant reviews and dissertations to identify additional papers. Results After applying inclusion and exclusion criteria to identified hits, this literature search retrieved six papers. Overall findings point towards a beneficial role of lifestyle interventions on mood, weight, blood pressure, lipid profile, physical activity and overall wellbeing. Methodological limitations include small sample size, gender ratio imbalance, inconsistencies in terms of laboratory measures, and lack of randomized control trials and absence of follow-up and longitudinal studies to determine the benefits of these factors on clinical and functional outcomes over time Conclusions Lifestyle interventions in BD targeting nutrition, exercise, wellbeing alongside beliefs, coping strategies and attitudes towards health show promise in reducing the risk of comorbid ailments in BD. There is still a strong need for studies a) developing interventions which are informed by the patient’s input and b) examining the effectiveness of such interventions targeting general wellness using well-controlled trials.

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Section: Introductionmentioning

confidence: 99%

Lifestyle interventions targeting dietary habits and exercise in bipolar disorder: A systematic review

Bauer

Gálvez

Hamilton

et al. 2016

Journal of Psychiatric Research

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“…More recent studies have demonstrated that this tissue is not responsible for energy storage only; it is a metabolically active organ with endocrine and paracrine activities that produces numerous substances, adipokines with pro- or anti-inflammatory functions included. 7 , 11 , 29 , 30 …”

Section: Discussionmentioning

confidence: 99%

“…28 In addition, C-reactive protein participates directly in the atherogenesis process and modulates endothelial function. 11 …”

Section: Discussionmentioning

confidence: 99%

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Quemerina E Fatores Relacionados Ao Risco Cardiovascular Em Crianças E Adolescentes: Uma Revisão Sistemática

Fontes

Neves

Cândido

2018

Rev. paul. pediatr.

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Objective: To review findings on chemerin and factors related to cardiovascular risk in children and adolescents.Data source: A systematic review was performed, according to the standards proposed by the PRISMA guideline, on PubMed, Science Direct, and Lilacs databases. The descriptor “chemerin” was used in combination with “children” and “adolescent”, no time limit applied. The research encompassed only original articles written in English, conducted with human subjects - the adult and elderly populations excluded -, as well as literature reviews, brief communications, letters, and editorials.Data synthesis: After independent analyses of the studies by two reviewers, seven articles meeting the eligibility criteria, published between 2012 and 2016, remained for the review. Cross-sectional, prospective, cohort, and case-control studies were included. The importance of chemerin adipokines on the risk factors for cardiovascular disease is demonstrated by its association with obesity and diabetes mellitus, as well as clinical, anthropometric, and biochemical parameters. However, the strength of evidence from these studies is relatively low, due to their heterogeneity, with several limitations such as small samples and consequent lack of representativeness, lack of standardization in dosage methods, cross-sectional design of most studies, and impossibility of extrapolating results.Conclusions: The deregulation of chemerin caused by increased adipose tissue may contribute to the development of cardiovascular diseases, suggesting that this adipokine may play a significant role in early identification of individuals at risk.

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“…Obesity is characterized by the excess of adipose tissue, associated with several comorbidities. Among these are coronary atherosclerosis, which comprises a series of inflammatory responses at cellular and molecular level, of which reactions are further exacerbated in obese patients 18 , 19 . Physical stress echocardiography has been widely used in the noninvasive investigation of the CAD 20 .…”

Section: Introductionmentioning

confidence: 99%

Assessment of myocardial ischemia in obese individuals undergoing physical stress echocardiography (PSE)

Silveira¹,

Sousa²,

Santos³

et al. 2015

Arquivos Brasileiros De Cardiologia

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BackgroundPhysical stress echocardiography is an established methodology for diagnosis and risk stratification of coronary artery disease in patients with physical capacity. In obese (body mass index ≥ 30 kg/m2) the usefulness of pharmacological stress echocardiography has been demonstrated; however, has not been reported the use of physical stress echocardiography in this growing population group.ObjectiveTo assess the frequency of myocardial ischemia in obese and non-obese patients undergoing physical stress echocardiography and compare their clinical and echocardiographic differences.Methods4,050 patients who underwent treadmill physical stress echocardiography were studied according to the Bruce protocol, divided into two groups: obese (n = 945; 23.3%) and non-obese (n = 3,105; 76.6%).ResultsThere was no difference regarding gender. Obese patients were younger (55.4 ± 10.9 vs. 57.56 ± 11.67) and had a higher frequency of hypertension (75.2% vs. 57, 2%; p < 0.0001), diabetis mellitus (15.2% vs. 10.9%; p < 0.0001), dyslipidemia (59.5% vs 51.9%; p < 0.0001), family history of coronary artery disease (59.3% vs. 55.1%; p = 0.023) and physical inactivity (71.4% vs. 52.9%, p < 0.0001). The obese had greater aortic dimensions (3.27 vs. 3.14 cm; p < 0.0001), left atrium (3.97 vs. 3.72 cm; p < 0.0001) and the relative thickness of the ventricule (33.7 vs. 32.8 cm; p < 0.0001). Regarding the presence of myocardial ischemia, there was no difference between groups (19% vs. 17.9%; p = 0.41). In adjusted logistic regression, the presence of myocardial ischemia remained independently associated with age, female gender, diabetes and hypertension.ConclusionObesity did not behave as a predictor of the presence of ischemia and the physical stress echocardiography. The application of this assessment tool in large scale sample demonstrates the feasibility of the methodology, also in obese.

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Valvoplastia mitral percutânea: 30 anos de experiência

Cited by 4 publications

References 9 publications

Lifestyle interventions targeting dietary habits and exercise in bipolar disorder: A systematic review

Lifestyle interventions targeting dietary habits and exercise in bipolar disorder: A systematic review

Quemerina E Fatores Relacionados Ao Risco Cardiovascular Em Crianças E Adolescentes: Uma Revisão Sistemática

Assessment of myocardial ischemia in obese individuals undergoing physical stress echocardiography (PSE)

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