Evolução da cirurgia cardiovascular: a saga brasileira. Uma história de trabalho, pioneirismo e sucesso

Braile, Domingo Marcolino; Gomes, Walter J.

doi:10.1590/s0066-782x2010000200002

Cited by 14 publications

(11 citation statements)

References 10 publications

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“…Mediastinitis is a serious infectious complication in the postoperative period of cardiovascular surgery [ 1 ] . The overall incidence of deep sternal wound infections (DSWI) ranges from 0.4% to 5%.…”

Section: Introductionmentioning

confidence: 99%

Cefazolin Concentration in the Mediastinal Adipose Tissue of Patients Undergoing Cardiac Surgery

Tchaick¹,

Figueira²,

Paz³

et al. 2017

Braz J Cardiovasc Surg

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ObjectiveTo measure the concentration of cefazolin in the anterior mediastinal adipose tissue of patients undergoing cardiac surgery, determining the variation of cefazolin concentration.MethodsTwo samples of approximately 1g of subcutaneous tissue were collected from 19 patients who underwent surgery in December 2015: the first sample was collected right after sternotomy and the second one, before sternal synthesis with steel wires. Antibiotic dosage was administered through high performance liquid chromatography.ResultsWe observed a positive and statistically significant correlation between time 1 and cefazolin concentration (r=0.489 and P=0.039). For time 2 and cefazolin concentration, there was a negative and statistically significant correlation between both variables (r=-0.793 and P<0.001). A negative correlation was also observed between body mass index and cefazolin concentration at time 2 (r=-0.510 and P=0.031). The regression model showed that every 1-minute increase in time 1 corresponded to an increase of 0.240 µg/dL in cefazolin concentration, whereas every 1-minute increase in time 2 corresponded to a reduction of 0.046 µg/dL in cefazolin concentration. As for body mass index, every 1 kg/m2 increase corresponded to a reduction of about 0.510 µg/dL in cefazolin concentration.ConclusionThere was a positive and significant correlation between the initial time of surgery and cefazolin level in the first dosage. The evaluation of the second dosage showed a negative and significant correlation between cefazolin level and the second time of dosage. The concentration of cefazolin is under the influence of body mass index.

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Section: Introductionmentioning

confidence: 99%

Cefazolin Concentration in the Mediastinal Adipose Tissue of Patients Undergoing Cardiac Surgery

Tchaick¹,

Figueira²,

Paz³

et al. 2017

Braz J Cardiovasc Surg

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“…The results demonstrate that the mortality rate of the study institution (5.3%) was slightly above the national mean of 4.8% 3 . With regard to the profile of patients that undergo CABG, in a study conducted in southern Brazil, the age varied from 32 to 86 years and the age group with the highest incidence was between 51 and 70 years, in which 688 individuals (68.5%) were male 9 .…”

Section: Discussionmentioning

confidence: 66%

“…Over the years CABG has received two essential contributions for the improvement of surgical outcomes throughout the world, both of which were introduced by Brazilian surgeons, namely: the technique of myocardial revascularization with cardiopulmonary bypass (CPB) and the use of double internal mammary artery grafts 3 .Thus, over the course of 40 years, CABG has undergone considerable development favoring this surgical practice. However, over the last 20 years there has been a significant change in the profile of patients undergoing CABG, which is usually performed with older individuals with more severe heart damage, most often with comorbidities associated with Cardiovascular Disease (CVD), representing greater risk for reoperations, complications and mortality 4 .…”

Section: Introductionmentioning

confidence: 99%

Factors associated with mortality in patients undergoing coronary artery bypass grafting

Koerich

Lanzoni

Erdmann

2016

Rev. Latino-Am. Enfermagem

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Objective: to investigate the factors associated with mortality in patients undergoing coronary artery bypass grafting in a cardiovascular referral hospital in Santa Catarina. Method: quantitative, exploratory, descriptive and retrospective study. The medical records of 1447 patients, from 2005 to 2013, were analyzed for statistically related variables, these being: profile, hospitalization diagnosis, risk factors for coronary artery disease, complications recorded during the hospitalization, length of hospitalization and cause of death. Results: the mortality rate was 5.3% during the study period. Death was more common in females and those of black skin color, with a mean age of 65 years. Acute myocardial infarction was the most common hospitalization diagnosis. The majority of the complications recorded during hospitalization were characterized by changes in the cardiovascular system, with longer hospitalization periods being directly related to death from septic shock. Conclusion: the data provide subsidies for nursing work with preventive measures and early detection of complications associated with coronary artery bypass grafting. This reinforces the importance of using the data as quality indicators, aiming to guarantee care guided by reliable information to guide managers in planning patient care and high complexity health services.

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“…In Brazil, more than 100,000 heart surgeries are performed each year [ 1 ] . In Recife, at Real Hospital Português de Beneficência in Pernambuco (RHP) only, 1,400 surgeries are performed every year, demonstrating the significance of the procedure in our country.…”

Section: Introductionmentioning

confidence: 99%

Impact of Respiratory Infection in the Results of Cardiac Surgery in a Tertiary Hospital in Brazil

Andrade¹,

Araújo²,

Neto³

2015

Revista Brasileira De Cirurgia Cardiovascular

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ObjectiveTo assess the impact of respiratory tract infection in the postoperative period of cardiac surgery in relation to mortality and to identify patients at higher risk of developing this complication.MethodsCross-sectional observational study conducted at the Recovery of Cardiothoracic Surgery, using information from a database consisting of a total of 900 patients operated on in this hospital during the period from 01/07/2008 to 1/07/2009. We included patients whose medical records contained all the information required and undergoing elective surgery, totaling 109 patients with two excluded. Patients were divided into two groups, WITH and WITHOUT respiratory tract infection, as the development or respiratory tract infection in hospital, with patients in the group without respiratory tract infection, the result of randomization, using for the pairing of the groups the type of surgery performed. The outcome variables assessed were mortality, length of hospital stay and length of stay in intensive care unit. The means of quantitative variables were compared using the Wilcoxon and student t-test.ResultsThe groups were similar (average age P=0.17; sex P=0.94; surgery performed P=0.85-1.00) Mortality in the WITH respiratory tract infection group was significantly higher (P<0.0001). The times of hospitalization and intensive care unit were significantly higher in respiratory tract infection (P<0.0001). The presence of respiratory tract infection was associated with the development of other complications such as renal failure dialysis and stroke P<0.00001 and P=0.002 respectively.ConclusionThe development of respiratory tract infection postoperative cardiac surgery is related to higher mortality, longer periods of hospitalization and intensive care unit stay.

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Evolução da cirurgia cardiovascular: a saga brasileira. Uma história de trabalho, pioneirismo e sucesso

Abstract: Mailing address: Domingo M. Braile • Av. J.K., 1505 -Tarraf -15091-450 -S. J. Rio

Cited by 14 publications

References 10 publications

Cefazolin Concentration in the Mediastinal Adipose Tissue of Patients Undergoing Cardiac Surgery

Cefazolin Concentration in the Mediastinal Adipose Tissue of Patients Undergoing Cardiac Surgery

Factors associated with mortality in patients undergoing coronary artery bypass grafting

Impact of Respiratory Infection in the Results of Cardiac Surgery in a Tertiary Hospital in Brazil

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