Angina pré-infarto na evolução intra-hospitalar de pacientes idosos com infarto agudo do miocárdio

Shian, Chiu Wen; Lima, Sandro Gonçalves de; Filho, Brivaldo Markman

doi:10.1590/s0066-782x2007001800004

Arq. Bras. Cardiol.

2007

DOI: 10.1590/s0066-782x2007001800004

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Angina pré-infarto na evolução intra-hospitalar de pacientes idosos com infarto agudo do miocárdio

Chiu Wen Shian

Sandro Gonçalves de Lima

Brivaldo Markman Filho

Abstract: SummaryBackground: Preinfarction angina (PIA) may be a marker of ischemic preconditioning. A decrease in infarct size, ventricular remodeling, congestive heart failure, cardiogenic shock or death was demonstrated in the presence of preinfarction angina. These findings were more evident in adults, but not in the elderly.

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Cited by 2 publications

References 26 publications

(46 reference statements)

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Pre- and post-conditioning hormesis in elderly mice, rats, and humans: its loss and restoration

Calabrese

2016

Biogerontology

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This paper assessed differences and similarities in the capacity for preconditioning (PC) and post-conditioning (PostC) to prevent ischemic reperfusion (IR) damage to the heart in the old/elderly as compared to young adult mice, rats, and humans. While PC reliably reduces myocardial ischemia-induced heart damage by about 30-60 % in young adult (2-3 months old) mice and rats, such protection begins to diminish in middle age (1 year old) and is fully lost in the old and elderly (≥18 months). Common rearing practices (i.e., no exercise; ad libitum feeding) are strongly associated with the loss of PC to prevent IR damage to the heart in old/elderly rodents. Substantial restoration of lost PC in old/elderly animal models is affected via various types of exercise and exercise protocols, several types of dietary interventions and pharmacological means. Evidence of PC-mediated cardioprotection in old/elderly humans via epidemiological investigations has been reported using multiple research protocols. These findings suggest the need for animal studies to better reflect human dietary, exercise and lifestyle patterns to enhance their extrapolative relevance.

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Pre- and post-conditioning hormesis in elderly mice, rats, and humans: its loss and restoration

Calabrese

2016

Biogerontology

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Descriptive analysis of the hospital morbimortality due to acute myocardial infarction in the federative republic of Brazil / Análise descritiva da morbimortalidade hospitalar por infarto agudo do miocárdio na república federativa do Brasil

Júnior

Nunes

Cruz

et al. 2021

R.pesq.:cuid.fundam.Online

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Objetivo: descrever a morbimortalidade hospitalar por Infarto Agudo do Miocárdio no Brasil entre 2012 e 2017. Métodos: estudo ecológico e descritivo realizado com dados do Sistema de Informações Hospitalares. As variáveis foram: as 5 regiões brasileiras, sexo, faixa etária e raça/cor. Resultados: houve registro de 502.106 internações e 58.050 óbitos, correspondendo a mortalidade de 11,56%. O sudeste obteve maior porcentagem de internações (50,14%) e óbitos (48,85%), enquanto o nordeste maior mortalidade (12,67%). Os homens se destacaram nas internações (63,46%) e óbitos (55,77%), enquanto as mulheres na mortalidade (13,99%). Pessoas entre 60 e 64 anos tiveram maior prevalência nas internações (15,46%) e idosos ≥ 80 anos nos óbitos (22,39%) e mortalidade (26,6%). Os autodeclarados brancos se destacaram nas internações (40,82%) e óbitos (39,46%) e os indígenas na mortalidade (17,86%). Conclusão: torna-se necessário o aperfeiçoamento das medidas de prevenção e controle, especialmente nos grupos com maior mortalidade.

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Angina pré-infarto na evolução intra-hospitalar de pacientes idosos com infarto agudo do miocárdio

Cited by 2 publications

References 26 publications

Pre- and post-conditioning hormesis in elderly mice, rats, and humans: its loss and restoration

Pre- and post-conditioning hormesis in elderly mice, rats, and humans: its loss and restoration

Descriptive analysis of the hospital morbimortality due to acute myocardial infarction in the federative republic of Brazil / Análise descritiva da morbimortalidade hospitalar por infarto agudo do miocárdio na república federativa do Brasil

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